JNK1 (MAPK8) (AK094000) Human Untagged Clone
CNY 5,792.00
CNY 6,270.00
货期*
现货
规格
Product images
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经常一起买 (4)
JNK1 (MAPK8) mouse monoclonal antibody, clone OTI4E3 (formerly 4E3)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for AK094000, the custom clone sequence may differ by one or more nucleotides
TTTTTGTTTGTACATTTTTCTCAGAAGAGGGTTCACTACTTTTATACAATTCTCAAAAGATCCCATGACC CAAAGAAGATGATAAATAGTGTTGATGTGGCATCCACCATTAAGGTTAAGTGTGGTGTGCCCTGTGAGTC TGAATGTCTACTTAAGAACCTTAAGTAGACATTAAGAACCTTAAGAAGGTTTTTTGTTTGTTTTTGTTTT TTTGTTGTTGAGATGGAGCCTTGCTCCGTTGCCCAGGCTGGAGAGCAGTGGCGCAATCTCAGCTCACTGC AACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTGCAGGCGCCT GCCCCCAAGCCCGGCTAATTTTTGTGTTTTTAGTAGAAATGGGGTTTCACCTTGTTGGTCAGGCTTGTCT CAAACTCCTGACCTCAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCAC CACACATGGCCGAAGGTTCTTCTTAAGTGGACATTCAGACTCACAAGGCACATCGCAGTTAACATCAGAA TCACTTCTGATGATAATATAAGTGAAGAATATAAGACAGGAGGCGCATATATTAATACCAGCAGAGCAGC TCCCAGTGTGTCTCTTCAGTTGGAACAGTTGTTGCAGTGGTCTACTTGCTGTCCAGAAGCCTGATAAGAG AAAAAGATTCCCATGGAGAAATGTTCTTCGAAGTGATAACCATGCTTACTCATAAGGAGTTGAAATGTAG CTTACCTGCTAGTTTTCCTCCAATAAAAATGTGTTTATCTTTCATTCTGATTTGTTGTGAAGCTTTTGCA CACTCTAATTTAAATCTTGGTAGCATATATCTAGTTGAGTACCCACAGTGCACCAGGCTCTATTCCAGGG CCCAGGAAATGGAAGTCAGTAAGACACGTGGTTCAAGCCCTCCCTGAGACAGATGGTAGTACAGAATGGT ATGTGGTATGATGTGCTGTAGCACAAGTTGCTGGTAGAGTGAAAAAGAAAGCTTCTACCCCAGCACTATC AAACCAACTTCAGAAACAGTGAATTACAGGAAAGATTAGTACTTCCTTTTAATATGATCCATTGTTGAGT GTCAAGGAATTGTTATTAATTAACATCCTTGAATCTTAGGCCGACATTTAACTGACTGTCATTGTAAGGA CACTGTTTGAAGTACTTCACATGTATAAAAATTTCCACTTAAACCATACATGCGTTGTGAGATTGGCTCT TAGACTTTGAAAAGTTCATTTTTGTTTACTTCTTTTACAGAATTGATATATAAGGAAGTTATGGACTTGG AGGAGAGAACCAAGAATGGAGTTATACGGGGGCAGCCCTCTCCTTTAGGTGCAGCAGTGATCAATGGCTC TCAGCATCCATCATCATCGTCGTCTGTCAATGATGTGTCTTCAATGTCAACAGATCCGACTTTGGCCTCT GATACAGACAGCAGTCTAGAAGCAGCAGCTGGGCCTCTGGGCTGCTGTAGATGACTACTTGGGCCATTGG GGGGTGGGAGGGATGGGGAGTCGGTTAGTCATTGATAGAACTACTTTGAAAACAATTCAGTGGTCTTATT TTTGGGTGATTTTTCAAAAAATGTAGAATTCATTTTGTAGTAAAGTAGTTTATTTTTTTTAATTTCAAGT GATGTAATTTAAAACCTAAGTTGTGTTTCAAAACAGCAACAAAACTGTATTGTATTTTTTTTGCTGTAAT TAACTGTATAATGTAAACCTAATTATTTTATCATGGTTTAAATTTTTTGCATATTTGCTTTATCTTATGC TGCTGATTTTTTTAACTGAATTTGTAAGATTTTGTTTATCAAAGCAACTATTATGTGGTAACTTGCCTAT ATCATGAATTATTTAAGATTTTTATAGTTTTTTTTAATTAGAATTTATTTCAGATGTTTTGTTCATGATA CTATCCTTCAGGGTTATGTGCTTATCAATGAAATAACCCCAGAGGAGTGAGGGAAAATAACTTGTAGCCA GTTATATTCAGGAATAACTACTGTAAATGATGAACGTGTTAGGAGACCTCCAATATTTGCTACTTGCCAA TCCTAATTTAGTTACAAGAATTGGTAGGCAATCCTACTTAATTTTGGCAAAAGCCCCGTCATCTAAATGG CAGAATAACTCAGAGCATGTCTTTGAAGATGCTGGGCGTCTACCACCACCTTATGTCCCCACCCTACCCA ACAAAAATAAGTAAAAAGAATATGGTGTATTCTACAAATTTGTGGCATGCTCAAAGTTTATGATCACATA AAGGCAAGAGGATACTTCATGAATAATACATTTCAATGCAAATAAACAGATGGTTCACTTCT >OriGene 5' read for AK094000 unedited
GGTGCACATTTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGGTTTTTAGT AGAAAGGGGTTTCACCTTGTTGGTCAGGCTTGTCTCAAACTCCTGACCTCAGGTGATCCA CCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACATGGCCGAAG GTTCTTCTTAAGTAGACATTCAGACTCACAAGGCACATCGCAGTTAACATCAGAATCACT TCTGATGATAATATAAGTGAAGAATATAAGACAGGAGGCGCATATATTAATACCAGCAGA GCAGCTCCCAGTGTGTCTCTTCAGTTGGAACAGTTGTTGCAGTGGTCTACTTGCTGTCCA GAAGCCTGATAAGAGAAAAAGATTCCCATGGAGAAATGTTCTTCGAAGTGATAACCATGC TTACTCATAAGGAGTTGAAATGTAGCTTACCTGCTAGTTTTCCTCCAATAAAAATGTGTT TATCTTTCATTCTGATTTGTTGTGAAGCTTTTGCACACTCTAATTTAAATCTTGGTAGCA TATATCTAGTTGAGTACCCACAGTGCACCAGGCTCTATTCCAGGGCCCAGGAAATGGAAG TCAGTAAGACACGTGGTTCAAGCCCTCCCTGAGACAGATGGTAGTACAGAATGGTATGTG GTATGATGTGCTGTAGCACAAGTTGCTGGTAGAGTGAAAAAGAAAGCTTCTACCCCAGCA CTATCAAACCAACTTCAGAAACAGTGAATTACAGGAAAGATTAGTACTTNCTTTTATATG ATCCATTGTTGAGTGTCAAGGAATTGNTATTAANTAACATCCTTGAATCTTTAGCCGACA TTTAACTGACTGTCATTGTAAGGACACTGTTTGAAGTACTTCACATGTATAAAAATTTCC ACTTAAACATACATGCGTTGTGAGAATGCCTCTTAGAA |
Restriction Sites | NotI-NotI |
ACCN | AK094000 |
Insert Size | 6000 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | AK094000.1 |
RefSeq Size | 2372 bp |
RefSeq ORF | 2372 bp |
Locus ID | 5599 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase |
Protein Pathways | Adipocytokine signaling pathway, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, GnRH signaling pathway, Insulin signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, Wnt signaling pathway |
Gene Summary | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016] |
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