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PTPN5 (NM_032781) Human Untagged Clone
CAT＃: SC103525
PTPN5 (untagged)-Human protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) (PTPN5), transcript variant 2
CNY 4,216.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PTPSTEP; STEP; STEP61 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_032781 edited
ATGAATTATGAGGGAGCCAGGAGTGAGAGAGAGAACCACGCTGCTGATGACTCCGAGGGA GGGGCCCTGGACATGTGCTGCAGTGAGAGGCTACCGGGTCTCCCCCAGCCGATAGTGATG GAGGCACTGGACGAGGCTGAAGGGCTCCAGGACTCACAGAGAGAGATGCCGCCACCCCCT CCTCCCTCGCCGCCCTCAGATCCAGCTCAGAAGCCACCACCTCGAGGCGCTGGGAGCCAC TCCCTCACTGTCAGGAGCAGCCTGTGCCTGTTCGCTGCCTCACAGTTCCTGCTTGCCTGT GGGGTGCTCTGGTTCAGCGGTTATGGCCACATCTGGTCACAGAACGCCACAAACCTCGTC TCCTCTTTGCTGACGCTCCTGAAACAGCTGGAACCCACGGCCTGGCTTGACTCTGGGACG TGGGGAGTCCCCAGTCTGCTGCTGGTCTTTCTGTCCGTGGGCCTGGTCCTCGTTACCACC CTGGTGTGGCACCTCCTGAGGACACCCCCAGAGCCACCCACCCCACTGCCCCCTGAGGAC AGGCGCCAGTCAGTGAGCCGCCAGCCCTCCTTCACCTACTCAGAGTGGATGGAGGAGAAG ATCGAGGATGACTTCCTGGACCTCGACCCGGTGCCCGAGACTCCTGTGTTTGATTGTGTG ATGGACATCAAGCCTGAGGCTGACCCCACCTCACTCACCGTCAAGTCCATGGGTCTGCAG GAGAGGAGGGGTTCCAATGTCTCCCTGACCCTGGACATGTGCACTCCGGGCTGCAACGAG GAGGGCTTTGGCTATCTCATGTCCCCACGTGAGGAGTCCGCCCGCGAGTACCTGCTCAGC GCCTCCCGTGTCCTCCAAGCAGAAGAGCTTCATGAAAAGGCCCTGGACCCTTTCCTGCTG CAGGCGGAATTCTTTGAAATCCCCATGAACTTTGTGGATCCGAAAGAGTACGACATCCCT GGGCTGGTGCGGAAGAACCGGTACAAAACCATACTTCCCAACCCTCACAGCAGAGTGTGT CTGACCTCACCAGACCCTGACGACCCTCTGAGTTCCTACATCAATGCCAACTACATCCGG GGCTATGGTGGGGAGGAGAAGGTGTACATCGCCACTCAGGGACCCATCGTCAGCACGGTC GCCGACTTCTGGCGCATGGTGTGGCAGGAGCACACGCCCATCATTGTCATGATCACCAAC ATCGAGGAGATGAACGAGAAATGCACCGAGTATTGGCCGGAGGAGCAGGTGGCGTACGAC GGTGTTGAGATCACTGTGCAGAAAGTCATTCACACGGAGGATTACCGGCTGCGACTCATC TCCCTCAAGAGTGGGACTGAGGAGCGAGGCCTGAAGCATTACTGGTTCACATCCTGGCCC GACCAGAAGACCCCAGACCGGGCCCCCCCACTCCTGCACCTGGTGCGGGAGGTGGAGGAG GCAGCCCAGCAGGAGGGGCCCCACTGTGCCCCCATCATCGTCCACTGCAGTGCAGGGATT GGGAGGACCGGCTGCTTCATTGCCACCAGCATCTGCTGCCAGCAGCTGCGGCAGGAGGGT GTAGTGGACATCCTGAAGACCACGTGCCAGCTCCGTCAGGACAGGGGCGGCATGATCCAG ACATGCGAGCAGTACCAGTTTGTGCACCACGTCATGAGCCTCTACGAAAAGCAGCTGTCC CACCAGTCCCCAGAATGA >OriGene 5' read for NM_032781 unedited
GGTGCACATTAGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGGGGCGAGGG AGCGCGCACGGAGCGCGGGACGGAGCGCCAGGCGGACGGACCGAAGGACGGAGGCACCGA AGGACGGACGCCCCCGCACACGCAGACGCACAGAGCTCGGCGCGGCCCCCGTCGCATACA CACTGGCACAGACACAAGCAGGGACACACGCAGACACACGCACACTCGCGCGCGCATCCT CCCGCCAGCCTGCCCGCCTGCTCGCCGGCGCCCGGAGCCCGCTCTGGCCGCTTGCTTTTT GCTGAGAAAGCTTCCTGCCCTGGAAGATGGCACCCTTCCCCATCCAGACACCTTGGGAAT GAATTATGAGGGAGCCAGGAGTGAGAGAGAGAACCACGCTGCTGATGACTCCGAGGGAGG GGCCCTGGACATGTGCTGCAGTGAGAGGCTACCGGGTCTCCCCCAGCCGATAGTGATGGA GGCACTGGACGAGGCTGAAGGGCTCCAGGACTCACAGAGAGAGATGCCGNCACCCCCTCC TTCCTCGCCGCCCTCAGATCCAGCTCAGAAGCCACCACCTCGAGGCGCTGGGAGCCACTC CCTCACTGTCAGGAGCAGCCTGTGCCTGTTCGCTGCCTCACAGTTTCTGCTTGCCTGTGG GGTGCTCTGGTTCAGCGGTTATGGCCACATCTGTTCACAGAACGCCACANACCTCGTCTC CTCTTTGCTGACGCTCCTGAAACAGCTGGAACCCCCAGGNCTGGCTTGACTCTGGGACGT TGGGAAGGTCCCAGTCTGCTGCTGGGTTTTCTGTCCGTGGCCCTGGTCTTGTTACCAACC TGGTGTGGGACCTCTGGAGACACCCCCGAAACACCCACCCACTGGCCCTGAGAGCAGGCC CATCAATGAACCGCAGCCCCCCTTAC >OriGene 3' read for NM_032781 unedited
ATAGCTATGNNACCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTTAGTTT TGCTCAAAATGCTCCGTTTATTGCTCTATTCAATGACCACGAGCGAATTATAAAAAGACA CCAAATGTCTCTGTCTGCCGTGGGATAAATATTTAAAGTCAGCAATAAAAACACGTGGCT CCAAGATAATACATGTTGCCAAAGAGTCATGCATGCCCTCCTGATGGGCTCTCAACACAC GCATGGACATGGGAACACACGCAGAGCAACACGCAGTGAGACTTCTGGGAAGGCTTTCCC ACAGTGACACAGAAAAATGTCTCACGTAGATCTGGGCTGAGTCCCCACCCAAACCTTGAG CTCCCCTCCCCTCCCCAACAGGGCCTAGATCCTCTGGGTTCTCCATGCCCCATCTGCCCC CTACCTTGCCAGTGCCTCACAGGCTGGGCACCCTCCTGAGAGCATCTGACACCCAGAGGC CACCCTGGCTGTGATGCCCACTCCAACCTAGAGAACTCTCCCTCAGCTGAAAGCTCTCTG GTGACCTTCTGGAGCTCCCCATGCCTAACTCCCCGTCATCTGCCTTTTGGGAGAAGTGCG GGTGAGGCCGAGGCAGGCAAGTCCGGTTGCTTAGGGGCTGGAGCTCATTACCCCTTCCTG GCTGAGGAGACACAGTGTCCGGTACAGAGGGCAGAGATGGATGGACAGACAGAACACATT GCAGCAGGACACAAAGTGTAGCACGGAAACATTCTGGATCAGGTATTGATGGAACCATCG TTAAAAACTGGAGCCCGGNGTCTGCGTGGTGGGGGTCAAGCCCCGGGGCCCCAAGCCTGG CCTGGCATGTTCCTTCCCGACCCTGCCCCCACTCCCCATATGTTCAGTANGAAGAGCATG CCTGAGGGTAGGGTCACGCCAGCTGACAAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_032781 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032781.2, NP_116170.2 |
| RefSeq Size | 2965 bp |
| RefSeq ORF | 1698 bp |
| Locus ID | 84867 |
| UniProt ID | P54829 |
| Domains | Y_phosphatase, PTPc_motif |
| Protein Families | Druggable Genome, Phosphatase, Transmembrane |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) has an alternate splice site in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform a. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61
,Won, S;Incontro, S;Nicoll, RA;Roche, KW;,
Proc. Natl. Acad. Sci. U.S.A.
,PubMed ID 27457929
[PTPN5]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217371 | PTPN5 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) (PTPN5), transcript variant 2 |
CNY 4,208.00 |
|
| RC217371L1 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) (PTPN5), transcript variant 2, Myc-DDK-tagged |
CNY 6,608.00 |
|
| RC217371L2 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) (PTPN5), transcript variant 2, mGFP tagged |
CNY 6,460.00 |
|
| RC217371L3 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) (PTPN5), transcript variant 2, Myc-DDK-tagged |
CNY 6,608.00 |
|
| RC217371L4 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) (PTPN5), transcript variant 2, mGFP tagged |
CNY 6,608.00 |
|
| RG217371 | PTPN5 (tGFP-tagged) - Human protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) (PTPN5), transcript variant 2 |
CNY 5,808.00 |
