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ORAI2 (NM_032831) Human Untagged Clone
CAT＃: SC103058
ORAI2 (untagged)-Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 2
CNY 2,400.00
CNY 3,990.00
| Cited in 4 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C7orf19; CBCIP2; MEM142B; TMEM142B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC103058 sequence for NM_032831 edited (data generated by NextGen Sequencing)
ATGAGTGCTGAGCTTAACGTGCCTATCGACCCCTCTGCTCCTGCCTGCCCTGAGCCCGGC CATAAGGGCATGGATTACCGGGACTGGGTCCGCCGCAGCTACCTGGAACTGGTCACCTCT AACCACCACTCGGTACAGGCCCTGTCGTGGCGGAAGCTCTACCTGAGCAGGGCCAAGCTG AAGGCCTCCAGCAGGACCTCCGCCCTCCTCTCCGGCTTTGCCATGGTGGCCATGGTGGAG GTGCAGCTGGAGACGCAGTACCAGTACCCGCGGCCGCTGCTGATTGCCTTCAGCGCCTGC ACCACGGTGCTGGTGGCCGTGCACCTGTTCGCCCTCCTCATCAGCACCTGCATCCTGCCC AATGTGGAGGCCGTGAGCAACATCCACAACCTGAACTCCATCAGCGAGTCCCCGCATGAG CGCATGCATCCCTACATCGAGCTGGCCTGGGGCTTCTCCACCGTGCTTGGCATCCTACTC TTCCTGGCCGAGGTGGTGCTGCTCTGCTGGATCAAGTTCCTCCCCGTGGATGCCCGGCGC CAGCCTGGCCCCCCACCTGGCCCTGGGAGTCACACGGGCTGGCAGGCCGCCCTGGTGTCC ACCATCATCATGGTGCCCGTGGGCCTCATCTTCGTGGTCTTCACCATCCACTTCTACCGC TCCCTGGTGCGCCACAAAACGGAGCGCCACAACCGCGAGATCGAGGAGCTCCACAAGCTC AAGGTCCAGCTGGACGGGCATGAGCGCAGCCTGCAGGTCTTGTGA Clone variation with respect to NM_032831.2 429 c=>t >OriGene 5' read for NM_032831 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTGACAATGTTTGCCACA GCCTCTGCCTGGAACCTGGCTCGTGCTGTGACCAGAAGGGAAAGGCGGCTGTTTGGCTCT TTCTCCCCCGCAAGGACCCGCTGACCCGCTGGATGGAGAGCAAAGGAGACCCCTCCCGAG CCGCTCACAGTCCTGTATTTGGCAGGTTTGGGAGCCTGAGGGGCCATCTCCCTGACACTC AGAGGCACTGCCTTGCAGACACCATCCGTGCTCCTGGGAAGGAACGTCCCAGGGATGGAA GTGCTTGGATGCGGTGCTGCTGGCTGCGGATGTGCGCAAGGAGATGGGATGGAGAGCCTG AGTTGGCATTCGTATAAATGACCTGCCTGGCTCCCACCATGAGTGCTGAGCTTAACGTGC CTATCGACCCCTCTGCTCCTGCCTGCCCTGAGCCCGGCCATAAGGGCATGGATTACCGGG ACTGGGTCCGCCGCAGCTACCTGGAACTGGTCACCTCTAACCACCACTCGGTACAGGCCC TGTCGTGGCGGAAGCTCTACCTGAGCAGGGCCAAGCTGAAGGCCTCCAGCAGGACCTCCG CCCTCCTCTCCGGCTNTGCCATGGTGGCCATGGTGGAGGTGCAGCTGGAGACGCAGTACC AGTACCCGCGGCCGCTGCTGATTGCCTTCAGCGCCTGCACCACGGTGNCTGGTGGGCCGT GCACCTGTTCGCCCTTCTCATCAGCACCTGCATCCTGCCCAATGGTGGAGGGCCGTGAGN NCACATCCACACCTGAACTNCATCAGCGAGTCCCCGCATGAGCGCATGCATCCCTACATC GAGCTGGCCTGGGGCTTCTTCACGTGCTTGGCATCCTACTCTTCTGGNCCGAGTGGTGCT GCTCTGCTGGATCAAGTCCTCCCCGTGNATGCCCNGCGCAGNCTGGCCCCCA >OriGene 3' read for NM_032831 unedited
NCCTCNTTGNACGCGGCCGCATTCTANGATCGGTTTTTTTTTTTTTTTTTTGAGAGGAGT CTGGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCCATCTCAGCTCACTGCAAGCTCTGC CTCCCGGGTTCACGCCATTGCCATTCTCCCGCCTCAGCCTCCCAAGTAGCTGGGGCTACA GGCGCCCGCCACCACGCCCAGCTAATTTTCTGTATTTTTTTAGTAGAGACAGGGTTTCAC CATGCTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCCGCCCACCTAGGCCTCC CAAAGTGCTGGGATTACAGGCGTGAGTCACTGCGCCCGGCCCCAGTGACTATTTATGAGA ACAAAAGACAAGGCATGGCTGACTCTCCAGGTTACAGCTGGAGAAGAGGGGAAAGGTGTT TGGTTGTACAAGCAGCTCAGGGCAGCTGGTGCTGCGGCGTGCATGTGCGGCCCGAGAGCG TGGCTTCGGGTCTACCAGATGCCTTCAAGGAAAAGGCCAGAACCTGCACTGCACGGCACA GTCACTGTGTGTGGTGGGACCCAGTGTCGGCTGAGAGGCCTGGAGGGGTCTTGCCTCCCT TGTAGTCACTTGGTGTCATAACAAGGAGGGCACTCATTTGGCCTGGGCCGGCCCCTGGCC CCACTATCCACAGGCCAGGCCCGGCCCAATGACCTTGCCCTAGCAGGAAAGTCCCCCAGG CTGTCCCCTTGCTGCCTAGGCCCATGGGCAAGCTGCACAGGCTCCGGNGCCTGAGGCAGA GCCCCCGCCTTCTGCTGCCCAGGCCCAGGGAGCGGCTGAGTCAGCCTTAGAGCCCTTCTG GGGCCCAAACTGGAGCCACTGCTGCGAGGTGGGGGGAAGGGTACTACTCCCTATCCGCAT ATATCATTATTCTACCACCCCCACCACC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_032831 |
| Insert Size | 2760 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_032831.1, NP_116220.1 |
| RefSeq Size | 2527 bp |
| RefSeq ORF | 765 bp |
| Locus ID | 80228 |
| UniProt ID | Q96SN7 |
| Protein Families | Transmembrane |
| Gene Summary | Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. Variants 1, 2, and 3 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported byt transcript alignments. |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Antibody-mediated targeting of the orai1 calcium channel inhibits T cell function
,Cox, JH;Hussell, S;Søndergaard, H;Roepstorff, K;Bui, JV;Deer, JR;Zhang, J;Li, ZG;Lamberth, K;Kvist, PH;Padkjær, S;Haase, C;Zahn, S;Odegard, VH;,
PLoS ONE Dec 2013.
,PubMed ID 24376610
[ORAI2]
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Calcium inhibition and calcium potentiation of orai1, orai2 and orai3 calcium-release-activated calcium channels
,Wayne I Dehaven, Jeremy T Smyth, Rebecca R Boyles, and James W Putney Jr,
J Biol Chem. 2007 Jun 15;282(24):17548-56.
[ORAI2]
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Orai proteins interact with TRPC channels and confer responsiveness to store depletion
,Y Liao, C Erxleben, E Yildirim, J Abramowitz, DL Armstrong, and L Birnbaumer,
Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4682-7.
[ORAI2]
|
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Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1
,Jason C. Mercer, Wayne I. DeHaven, Jeremy T. Smyth, Barbara Wedel, Rebecca R. Boyles, Gary S. Bird, and James W. Putney, Jr,
J. Biol. Chem., 2006 Aug 25;281(34):24979-90.
[ORAI2]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221137 | ORAI2 (Myc-DDK-tagged)-Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 2 |
CNY 2,400.00 |
|
| RC221137L1 | Lenti ORF clone of Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 2, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC221137L2 | Lenti ORF clone of Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC221137L3 | Lenti ORF clone of Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC221137L4 | Lenti ORF clone of Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG221137 | ORAI2 (tGFP-tagged) - Human ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 2 |
CNY 4,000.00 |
