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IL1RA (IL1RN) (NM_173843) Human Untagged Clone
CAT＃: SC101242
IL1RN (untagged)-Human interleukin 1 receptor antagonist (IL1RN), transcript variant 4
CNY 1,200.00
CNY 3,990.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC101242 sequence for NM_173843 edited (data generated by NextGen Sequencing)
ATGCAAGCCTTCAGAATCTGGGATGTTAACCAGAAGACCTTCTATCTGAGGAACAACCAA CTAGTTGCCGGATACTTGCAAGGACCAAATGTCAATTTAGAAGAAAAGATAGATGTGGTA CCCATTGAGCCTCATGCTCTGTTCTTGGGAATCCATGGAGGGAAGATGTGCCTGTCCTGT GTCAAGTCTGGTGATGAGACCAGACTCCAGCTGGAGGCAGTTAACATCACTGACCTGAGC GAGAACAGAAAGCAGGACAAGCGCTTCGCCTTCATCCGCTCAGACAGTGGCCCCACCACC AGTTTTGAGTCTGCCGCCTGCCCCGGTTGGTTCCTCTGCACAGCGATGGAAGCTGACCAG CCCGTCAGCCTCACCAATATGCCTGACGAAGGCGTCATGGTCACCAAATTCTACTTCCAG GAGGACGAGTAG Clone variation with respect to NM_173843.2 69 t=>c >OriGene 5' read for NM_173843 unedited
NGTTAGTTTTTGTNNTNNTTTTTTTTAGGGTGGNNGNGGNTTTGGTNGNGGGGGTGTTGT TTTGTGTTGTTTGGGGGTGGCGTGGGTTTAGAGACGATCTGCCGACCCTCTGGGGAGAAA ATCCAGCAAGATGCAAGCCTTCAGAATCTGGGATGTTAACCAGAAGACCTTCTATCTGAG GAACAACCAACTAGTTGCCGGATACTTGCAAGGACCAAATGTCAATTTAGAAGAAAAGAT AGATGTGGTACCCATTGAGCCTCATGCTCTGTTCTTGGGAATCCATGGAGGGAAGATGTG CCTGTCCTGTGTCAAGTCTGGTGATGAGACCAGACTCCAGCTGGAGGCAGTTAACATCAC TGACCTGAGCGAGAACAGAAAGCAGGACAAGCGCTTCGCCTTCATCCGCTCAGACAGTGG CCCCACCACCAGTTTTGAGTCTGCCGCCTGCCCCGGTTGGTTCCTCTGCACAGCGCTGGG AGCTGACCAGCCCGTCGGCCTCACCAATATGCCTGACGAAAGCGTCTGGGTCACCAAAAT CTAGCTCCAGTAGGACCAGGTGTGCTGCCCAGGCCCGGGCCGATCCCCTTCCTCGATGGG CAGGGACCGCAGGCACTGCACAGTCCCCCTGCCCCCGGGGCTCCCCGCCTTTGGCGCCCC CTGGCGCACACACCCTTGAGGCGCCGGACCCCCACAAAGCGTCCGCGGCACCGGGGAAGC GGGGACGTGCGCCTCCCCGGCGACGGACGAGGCCGCCCAGCTCGCCCCCCCACAGGGACG TTAAGAGGGGGCACACTCGGAGCAACGAGAGCCACGGGCACAAGGCCTTTCCCCGTCGCC TCGGATATGAGTAGAACACGACCCGAGACACCATGGAACAAACTGGTACGACTCTTCTGA AACAGGGTTCATCCTCACCGATATTACAACCAACACCGGCGCCAGCAAACACCCG |
| Restriction Sites | Please inquire |
| ACCN | NM_173843 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_173843.1, NP_776215.1 |
| RefSeq Size | 1973 bp |
| RefSeq ORF | 432 bp |
| Locus ID | 3557 |
| UniProt ID | P18510 |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020] Transcript Variant: This variant (4) contains a distinct internal exon compared to variant 2. This results in translation from a downstream start codon, and an isoform (4) that has a shorter N-terminus, as compared to the longest isoform (2). Variants 4 and 5 both encode the same isoform (4). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202447 | IL1RN (Myc-DDK-tagged)-Human interleukin 1 receptor antagonist (IL1RN), transcript variant 4 |
CNY 1,200.00 |
|
| RC202447L1 | Lenti ORF clone of Human interleukin 1 receptor antagonist (IL1RN), transcript variant 4, Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC202447L2 | Lenti ORF clone of Human interleukin 1 receptor antagonist (IL1RN), transcript variant 4, mGFP tagged |
CNY 5,890.00 |
|
| RC202447L3 | Lenti ORF clone of Human interleukin 1 receptor antagonist (IL1RN), transcript variant 4, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202447L4 | Lenti ORF clone of Human interleukin 1 receptor antagonist (IL1RN), transcript variant 4, mGFP tagged |
CNY 5,890.00 |
|
| RG202447 | IL1RN (tGFP-tagged) - Human interleukin 1 receptor antagonist (IL1RN), transcript variant 4 |
CNY 2,800.00 |
