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GSTM4 (NM_147148) Human Untagged Clone
CAT＃: SC101187
GSTM4 (untagged)-Human glutathione S-transferase mu 4 (GSTM4), transcript variant 2
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GSTM4-4; GTM4 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_147148, the custom clone sequence may differ by one or more nucleotides
ATGTCCATGACACTGGGGTACTGGGACATCCGCGGGCTGGCCCACGCCATCCGCCTGCTCCTGGAATACA CAGACTCAAGCTACGAGGAAAAGAAGTATACGATGGGGGACGCTCCTGACTATGACAGAAGCCAGTGGCT GAATGAAAAATTCAAGCTGGGCCTGGACTTTCCCAATCTGCCCTACTTGATTGATGGGGCTCACAAGATC ACCCAGAGCAACGCCATCCTGTGCTACATTGCCCGCAAGCACAACCTGTGTGGGGAGACAGAAGAGGAGA AGATTCGTGTGGACATTTTGGAGAACCAGGCTATGGACGTCTCCAATCAGCTGGCCAGAGTCTGCTACAG CCCTGACTTTGAGAAACTGAAGCCAGAATACTTGGAGGAACTTCCTACAATGATGCAGCACTTCTCACAG TTCCTGGGGAAGAGGCCATGGTTTGTTGGAGACAAGATCACCTTTGTAGATTTCCTCGCCTATGATGTCC TTGACCTCCACCGTATATTTGAGCCCAACTGCTTGGACGCCTTTCCAAATCTGAAGGACTTCATCTCCCG CTTTGAGGTTTCCTGTGGCATAATGTGA >OriGene 5' read for NM_147148 unedited
CTCATTCACCCGCCCGTTGNAGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATA AGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCG CGAATTCGGCACGAGACTCCTTCCAGCCAGTGAGGATCCAGCAACCTGCTCCGTGCCTCC CGCGCCTGTTGGTTGGAAGTGACGACCTTGAAGATCGGCCGGTTGGAAGTGACGACCTTG AAGATCGGCGGGCGCAGCGGGGCCGAGGGGGCGGGTCTGGCGCTAGGTCCAGCCCCTGCG TGCCGGGAACCCCAGAGGAGGTCGCAGTTCAGCCCAGCTGAGGCCTGTCTGCAGAATCGA CACCAACCAGCATCATGTCCATGACACTGGGGTACTGGGACATCCGCGGGCTGGCCCACG CCATCCGCCTGCTCCTGGAATACACAGACTCAAGCTACGAGGAAAAGAAGTATACGATGG GGGACGCTCCTGACTATGACAGAAGCCAGTGGCTGAATGAAAATTCAAGCTGGGCCTGGA CTTTTCCAATCTGCCCTACTTGATTGATGGGGCTCACAAGATCACCCAGAGCAACGCCAT CCTGTGCTACATTGCCCGCAAGCACAACCTGTGTGGGGAGACAGAAGAAGAGAAGATTCG TGTGGACATTTTGGAGAACCAGCTATGGACGTCTNCAATCAGCTGGCCAGAGTCTGCTAC AGCCCTGACTTTGANGAACTGAAGCCCAGATACTTGGAGGAACTTNCTAACATGATGCAG CACTTCTCACAGTTTCCTGGGNAAGAAGCCATGNTTTGTTGGAGACAAGATCACTTTTGG AAATTCCCTCGCCTATGAAGTCCTGGACTCCCACGTAATTTTGGACCCACTGCTTGGACC CTTTCCAAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_147148 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_147148.1, NP_671489.1 |
| RefSeq Size | 1374 bp |
| RefSeq ORF | 588 bp |
| Locus ID | 2948 |
| UniProt ID | Q03013 |
| Domains | GST_N, GST_C |
| Protein Pathways | Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450 |
| Gene Summary | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) uses an alternate in-frame exon in the 3' coding region and 3' UTR, compared to variant 1. It encodes a protein which has a shorter and distinct C-terminus compared to isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215534 | GSTM4 (Myc-DDK-tagged)-Human glutathione S-transferase mu 4 (GSTM4), transcript variant 2 |
CNY 2,400.00 |
|
| RC215534L3 | Lenti ORF clone of Human glutathione S-transferase mu 4 (GSTM4), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215534L4 | Lenti ORF clone of Human glutathione S-transferase mu 4 (GSTM4), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG215534 | GSTM4 (tGFP-tagged) - Human glutathione S-transferase mu 4 (GSTM4), transcript variant 2 |
CNY 4,370.00 |
