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LARGE2 (NM_152312) Human Untagged Clone
CAT＃: SC100883
GYLTL1B (untagged)-Human glycosyltransferase-like 1B (GYLTL1B)
CNY 5,288.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GYLTL1B; PP5656 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_152312 edited
ATGCTGCCCCGAGGGCGCCCCCGGGCGCTGGGGGCCGCCGCGCTGTTGCTGCTGCTGCTG CTGCTCGGATTCCTCCTGTTCGGTGGGGACCTGGGGTGTGAGCGCCGCAAGCCTGGCGGG CGAGCGGGGGCCCCGGGATGCTTCCCCGGCCCGCTCATGCCACGTGTCCCCCCAGACGGG AGGCTGCGGAGAGCCGCCGCCCTCGACGGAGACCCGGGGGCCGGCCCCGGGGACCACAAC CGCTCCGACTGCGGCCCGCAGCCGCCGCCGCCGCCCAAGTGCGAGCTCTTGCATGTGGCC ATCGTGTGTGCGGGGCATAACTCCAGCCGAGACGTCATCACCCTGGTGAAGTCCATGCTC TTCTACAGGAAAAATCCACTGCACCTCCACTTGGTGACTGACGCCGTGGCCAGAAACATC CTGGAGACGCTCTTCCACACATGGATGGTGCCTGCTGTCCGTGTCAGCTTTTATCATGCC GACCAGCTCAAGCCCCAGGTCTCCTGGATCCCCAACAAGCACTACTCCGGCCTCTATGGG CTAATGAAGCTGGTGCTGCCCAGTGCCTTGCCTGCTGAGCTGGCCCGCGTCATTGTCCTG GACACGGATGTCACCTTCGCCTCTGACATCTCGGAGCTCTGGGCCCTCTTTGCTCACTTT TCTGACACGCAGGCGATCGGTCTTGTGGAGAACCAGAGTGACTGGTACCTGGGCAACCTC TGGAAGAACCACAGGCCCTGGCCTGCCTTGGGCCGGGGATTTAACACAGGTGTGATCCTG CTGCGGCTGGACCGGCTCCGGCAGGCTGGCTGGGAGCAGATGTGGAGGCTGACAGCCAGG CGGGAGCTCCTTAGCCTGCCTGCCACCTCACTGGCTGACCAGGACATCTTCAACGCTGTG ATCAAGGAGCACCCGGGGCTAGTGCAGCGTCTGCCTTGTGTCTGGAATGTGCAGCTGTCA GATCACACACTGGCCGAGCGCTGCTACTCTGAGGCGTCTGACCTCAAGGTGATCCACTGG AACTCACCAAAGAAGCTTCGGGTGAAGAACAAGCATGTGGAATTCTTCCGCAATTTCTAC CTGACCTTCCTGGAGTACGATGGGAACCTGCTGCGGAGAGAGCTCTTTGTGTGCCCCAGC CAGCCCCCACCTGGTGCTGAGCAGTTGCAGCAGGCCCTGGCACAACTGGACGAGGAAGAC CCCTGCTTTGAGTTCCGGCAGCAGCAGCTCACTGTGCACCGTGTGCATGTCACTTTCCTG CCCCATGAACCGCCACCCCCCCGGCCTCACGATGTCACCCTTGTGGCCCAGCTGTCCATG GACCGGCTGCAGATGTTGGAAGCCCTGTGCAGGCACTGGCCTGGCCCCATGAGCCTGGCC TTGTACCTGACAGACGCAGAAGCTCAGCAGTTCCTGCATTTCGTCGAGGCCTCACCAGTG CTTGCTGCCCGGCAGGACGTGGCCTACCATGTGGTGTACCGTGAGGGGCCCCTATACCCC GTCAACCAGCTTCGCAACGTGGCCTTGGCCCAGGCCCTCACGCCTTACGTCTTCCTCAGT GACATTGACTTCCTGCCTGCCTATTCTCTCTACGACTACCTCAGGGCCTCCATTGAGCAG CTGGGGCTGGGCAGCCGGCGCAAGGCAGCACTGGTGGTGCCGGCATTTGAGACCCTGCGC TACCGCTTCAGCTTCCCCCATTCCAAGGTGGAGCTGTTGGCCTTGCTGGATGCGGGCACT CTCTACACCTTCAGGTACCACGAGTGGCCCCGAGGCCACGCACCCACAGACTATGCCCGC TGGCGGGAGGCTCAGGCCCCGTACCGTGTGCAATGGGCGGCCAACTATGAACCCTACGTG GTGGTGCCACGAGACTGTCCCCGCTATGATCCTCGCTTTGTGGGCTTCGGCTGGAACAAA GTGGCCCACATTGTGGAGCTGGATGCCCAGGAATATGAGCTCCTGGTGCTGCCCGAGGCC TTCACCATCCATCTGCCCCACGCTCCAAGCCTGGACATCTCCCGCTTCCGCTCCAGCCCC ACCTATCGTGACTGCCTCCAGGCCCTCAAGGACGAATTCCACCAGGACTTGTCCCGCCAC CATGGGGCTGCTGCCCTCAAATACCTCCCAGCCCTGCAGCAGCCCCAGAGCCCTGCCCGA GGCTGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_152312 |
| Insert Size | 2200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152312.2, NP_689525.2 |
| RefSeq Size | 2528 bp |
| RefSeq ORF | 2166 bp |
| Locus ID | 120071 |
| UniProt ID | Q8N3Y3 |
| Protein Families | Transmembrane |
| Gene Summary | Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide. Has a higher activity toward alpha-dystroglycan than LARGE.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206132 | GYLTL1B (Myc-DDK-tagged)-Human glycosyltransferase-like 1B (GYLTL1B) |
CNY 5,280.00 |
|
| RC206132L3 | Lenti ORF clone of Human glycosyltransferase-like 1B (GYLTL1B), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC206132L4 | Lenti ORF clone of Human glycosyltransferase-like 1B (GYLTL1B), mGFP tagged |
CNY 7,700.00 |
|
| RG206132 | GYLTL1B (tGFP-tagged) - Human glycosyltransferase-like 1B (GYLTL1B) |
CNY 6,370.00 |
