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KBTBD6 (NM_152903) Human Untagged Clone
CAT＃: SC100640
KBTBD6 (untagged)-Human kelch repeat and BTB (POZ) domain containing 6 (KBTBD6)
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_152903, the custom clone sequence may differ by one or more nucleotides
ATGCAGTCCCGGGAAGACGCCCCGCGCTCTCGCCGCCTAGCCAGTCCCCGTGGTGGGAAGCGGCCCAAGA AGATTCACAAACCCACAGTTTCGGCCTTTTTCACGGGTCCAGAGGAATTAAAGGACACGGCCCATTCTGC AGCCCTGCTGGCACAGCTCAAGTCCTTCTACGATGCGCGGCTGCTGTGTGATGTGACCATCGAGGTGGTG ACGCCTGGCAGCGGGCCTGGCACGGGTCGCCTGTTCCCCTGCAACCGCAATGTGCTGGCCGCGGCATGTC CCTACTTCAAGAGCATGTTCACAGGTGGCATGTACGAGAGCCAGCAGGCCAGCGTGACCATGCACGATGT GGACGCCGAGTCCTTCGAGGTGTTGGTCGACTACTGCTACACGGGTCGTGTGTCTCTCAGTGAGGCCAAC GTGGAGCGCCTGTACGCGGCCTCCGACATGCTACAGCTGGAATATGTGCGGGAAGCCTGTGCCTCCTTCT TAGCCCGACGTCTTGACCTGACCAACTGCACCGCCATCCTCAAGTTTGCAGATGCCTTTGGCCATCGCAA GCTGCGATCCCAGGCCCAGTCCTATATAGCTCAGAACTTCAAGCAACTCAGCCACATGGGTTCAATTCGG GAGGAGACTCTAGCAGATCTGACCCTGGCCCAGCTGCTGGCTGTCCTGCGCTTGGATAGTCTGGACGTGG AGAGTGAGCAGACAGTGTGCCATGTGGCAGTGCAGTGGCTGGAGGCTGCTCCCAAAGAGCGGGGTCCCAG TGCTGCAGAAGTCTTCAAGTGCGTGCGCTGGATGCACTTCACTGAAGAAGATCAGGACTACTTAGAAGGG CTGCTGACCAAGCCCATCGTGAAGAAGTACTGCCTGGACGTTATTGAAGGGGCCCTGCAGATGCGCTATG GTGACCTGTTGTACAAGTCTCTGGTGCCAGTGCCAAACAGCAGCAGCAGCAGTAGCAGCAGCAACTCTCT TGTATCTGCAGCAGAAAATCCACCCCAGAGACTGGGTATGTGTGCCAAGGAGATGGTGATCTTCTTTGGA CACCCCAGAGATCCCTTTCTCTGCTGTGATCCATACTCGGGGGACCTTTACAAAGTGCCGTCACCTTTGA CCTGTCTGGCTCACACTAGGACTGTCACCACTCTAGCTGTCTGTATCTCTCCTGACCATGACATCTATCT AGCTGCTCAGCCCAGGACAGACCTCTGGGTGTATAAACCAGCTCAGAATAGTTGGCAGCAACTTGCAGAT CGCTTGCTGTGTCGTGAGGGCATGGATGTGGCATATCTCAATGGCTATATCTACATTTTGGGGGGGCGAG ACCCTATTACTGGAGTTAAGTTGAAGGAAGTGGAATGCTACAATGTTAAGAGAAACCAGTGGGCATTGGT GGCTCCACTGCCCCATTCTTTTTTATCCTTTGACCTAATGGTAATTCGAGACTATCTCTATGCTCTCAAC AGTAAGCGCATGTTCTGTTATGATCCTAGCCACAATATGTGGCTGAAGTGCGTTTCTCTGAAGCGCAATG ACTTTCAGGAAGCCTGCGTCTTCAATGAGGAGATCTATTGTATCTGTGATATCCCAGTCATGAAGGTCTA CAACCCAGTTAGGGCAGAATGGAGGCAAATGAATAATATTCCCTTGGTCTCAGAGACCAACAACTACAGA ATTATCAAGCATGGCCAAAAATTGTTGCTCATCACCTCTCGCACCCCACAGTGGAAAAAGAACCGGGTGA CTGTGTATGAATATGATATTAGGGGAGACCAATGGATTAATATAGGTACCACATTAGGCCTCTTGCAGTT TGATTCTAACTTTTTTTGCCTCTCTGCTCGTGTTTATCCTTCCTGCCTTGAACCTGGTCAGAGTTTCCTC ACTGAAGAAGAAGAAATACCAAGTGAGTCTAGCACTGAATGGGACTTAGGTGGATTCAGTGAGCCAGACT CTGAGTCAGGAAGTTCAAGTTCTCTTTCTGATGATGATTTTTGGGTGCGTGTAGCGCCTCAGTGA >OriGene 5' read for NM_152903 unedited
NNGGGTCGGTCCAGATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGAAA CGGCCCATTCTGCAGCCCTGCTGGCACAGCTCAAGTCCTTCTACGATGCGCGGCTGCTGT GTGATGTGACCATCGAGGTGGTGACGCCTGGCAGCGGGCCTGGCACGGGTCGCCTGTTCC CCTGCAACCGCAATGTGCTGGCCGCGGCATGTCCCTACTTCAAGAGCATGTTCACAGGTG GCATGTACGAGAGCCAGCAGGCCAGCGTGACCATGCACGATGTGGACGCCGAGTCCTTCG AGGTGTTGGTCGACTACTGCTACACGGGTCGTGTGTCTCTCAGTGAGGCCAACGTGGAGC GCCTGTACGCGGCCTCCGACATGCTACAGCTGGAATATGTGCGGGAAGCCTGTGCCTCCT TCTTAGCCCGACGTCTTGACCTGACCAACTGCACCGCCATCCTCAAGTTTGCAGATGCCT TTGGCCATCGCAAGCTGCGATCCCAGGCCCAGTCCTATATAGCTCAGAACTTCAAGCAAC TCAGCCACATGGGTTCAATTCGGGAGGAGACTCTAGCAGATCTGACCCTGGCCCAGCTGC TGGCTGTCCTGCGCTTGGATAGTCTGGACGTGGAGAGTGAGCAGACAGTGTGCCATGTGG CAGTGCAGTGGCTGGAGGCTGCTCCCAAAGAGCGGNGTCCCAGTGCTGCAGAAGTCTTCA AGTGCGTGCGCTGGATGCACTTCACTGAAGAAGATCAGGACTACTTAGAAGGGCTGCTGA CCAAGCCCATCGTGAAGAAGTACTGCCTGNACGTTATTGAAGGGGCCCTGCAGATGCGCT ATGGTGACCCTGTGTACAAGTCTCTGGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_152903 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152903.4, NP_690867.3 |
| RefSeq Size | 5228 bp |
| RefSeq ORF | 2025 bp |
| Locus ID | 89890 |
| UniProt ID | Q86V97 |
| Domains | BTB, Kelch |
| Gene Summary | As part of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex functions as a substrate adapter for the RAC1 guanine exchange factor (GEF) TIAM1, mediating its 'Lys-48' ubiquitination and proteasomal degradation (PubMed:25684205). By controlling this ubiquitination, regulates RAC1 signal transduction and downstream biological processes including the organization of the cytoskeleton, cell migration and cell proliferation (PubMed:25684205). Ubiquitination of TIAM1 requires the membrane-associated protein GABARAP which may restrict locally the activity of the complex (PubMed:25684205).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200950 | KBTBD6 (Myc-DDK-tagged)-Human kelch repeat and BTB (POZ) domain containing 6 (KBTBD6) |
CNY 3,990.00 |
|
| RC200950L3 | Lenti ORF clone of Human kelch repeat and BTB (POZ) domain containing 6 (KBTBD6), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200950L4 | Lenti ORF clone of Human kelch repeat and BTB (POZ) domain containing 6 (KBTBD6), mGFP tagged |
CNY 5,890.00 |
|
| RG200950 | KBTBD6 (tGFP-tagged) - Human kelch repeat and BTB (POZ) domain containing 6 (KBTBD6) |
CNY 4,370.00 |
