United States
Germany
Japan
United Kingdom
China
MARS2 (NM_138395) Human Untagged Clone
CAT＃: SC100504
MARS2 (untagged)-Human methionyl-tRNA synthetase 2, mitochondrial (MARS2), nuclear gene encoding mitochondrial protein
CNY 4,424.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | COXPD25; MetRS; mtMetRS |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC100504 sequence for NM_138395 edited (data generated by NextGen Sequencing)
ATGCTGCGAACGTCCGTCCTCCGCCTGCTAGGACGCACGGGGGCTAGTAGGCTGTCTCTC CTGGAGGACTTCGGCCCACGCTACTACAGTTCGGGCTCCCTCAGTGCCGGCGATGATGCT TGTGATGTGCGCGCCTACTTCACTACACCCATTTTCTACGTGAACGCGGCGCCGCACATC GGGCACCTGTACTCGGCACTACTGGCGGACGCCCTATGCCGCCACCGTCGCCTCCGAGGT CCCAGCACGGCCGCCACGCGATTCTCCACTGGTACCGACGAGCACGGGCTGAAGATTCAG CAGGCAGCAGCTACCGCGGGCCTGGCCCCGACCGAGCTGTGCGACCGAGTCTCTGAGCAG TTCCAGCAGCTTTTCCAGGAGGCCGGTATCTCCTGCACAGATTTCATCCGCACCACGGAG GCCCGGCACCGGGTGGCTGTGCAGCACTTCTGGGGGGTGCTTAAGTCCCGCGGTCTGCTC TACAAGGGCGTCTATGAAGGTTGGTATTGCGCTTCCGACGAGTGCTTCCTGCCTGAGGCC AAGGTCACCCAGCAGCCGGGCCCATCGGGGGATTCGTTTCCTGTATCTCTCGAGAGCGGG CATCCAGTCTCCTGGACCAAGGAAGAAAACTACATTTTCAGGCTTTCCCAGTTCCGGAAG CCACTCCAGCGGTGGCTGCGGGGCAACCCTCAGGCGATCACCCCCGAACCATTTCATCAC GTAGTTCTTCAGTGGCTGGACGAGGAGCTGCCCGACCTGTCCGTGTCTCGCAGAAGTAGC CACTTGCACTGGGGCATTCCGGTGCCCGGGGATGATTCGCAGACCATCTATGTATGGCTG GATGCCCTGGTCAACTACCTCACTGTAATTGGCTACCCAAATGCTGAGTTCAAATCTTGG TGGCCGGCCACCTCTCATATCATAGGTAAGGACATTCTCAAATTCCATGCCATCTATTGG CCTGCCTTCCTGTTAGGGGCCGGCATGAGCCCGCCACAGCGCATCTGTGTCCATTCCCAC TGGACAGTCTGTGGCCAAAAGATGTCCAAGAGCTTGGGCAACGTGGTGGATCCTAGGACT TGCCTTAACCGCTATACCGTGGATGGCTTCCGCTACTTTCTCCTTCGGCAGGGCGTCCCC AACTGGGACTGTGACTACTATGATGAAAAGGTGGTTAAGTTGCTGAACTCCGAGCTGGCA GATGCCTTGGGAGGTCTCTTGAACCGATGCACTGCCAAAAGAATAAATCCTTCTGAGACC TACCCAGCCTTCTGCACTACCTGCTTCCCTAGTGAGCCAGGGTTGGTGGGGCCGTCAGTT CGTGCTCAGGCAGAGGATTATGCTCTGGTGAGCGCAGTGGCCACTTTGCCAAAGCAGGTA GCAGACCACTATGATAACTTTCGGATATATAAGGCTCTGGAGGCCGTGTCCAGCTGTGTC CGGCAAACTAATGGTTTTGTCCAAAGGCATGCACCATGGAAGCTGAACTGGGAGAGCCCA GTGGATGCTCCCTGGCTGGGTACTGTGCTTCATGTGGCCTTGGAATGTTTGCGAGTCTTT GGGACTTTGCTGCAGCCTGTCACCCCAAGCCTAGCTGACAAGCTGCTGTCTAGGCTGGGG GTCTCTGCCTCAGAGAGGAGTCTTGGAGAGCTCTATTTCTTGCCTCGATTCTATGGACAT CCATGCCCTTTTGAAGGGAGGAGGCTGGGACCTGAAACTGGGCTTTTGTTTCCAAGACTA GACCAGTCCAGGACTTGGCTGGTGAAAGCCCACCGGACCTAG Clone variation with respect to NM_138395.3 >OriGene 5' read for NM_138395 unedited
GCATTTCCCCCGCCCGTTGNCGCATTGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATA AGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCC GCGAATTCGGCACGAGGGCACCATGCTGCGAACGTCCGTCCTCCGCCTGCTAGGACGCAC GGGGGCTAGTAGGCTGTCTCTCCTGGAGGACTTCGGCCCACGCTACTACAGTTCGGGCTC CCTCAGTGCCGGCGATGATGCTTGTGATGTGCGCGCCTACTTCACTACACCCATTTTCTA CGTGAACGCGGCGCCGCACATCGGGCACCTGTACTCGGCACTACTGGCGGACGCCCTATG CCGCCACCGTCGCCTCCGAGGTCCCAGCACGGCCGCCACGCGATTCTCCACTGGTACCGA CGAGCACGGGCTGAAGATTCAGCAGGCAGCAGCTACCGCGGGCCTGGCCCCGACCGAGCT GTGCGACCGAGTCTCTGAGCAGTTCCAGCAGCTTTTCCAGGAGGCCGGTATCTCCTGCAC AGATTTCATCCGCACCACGGAGGCCCGGCACCGGGTGGCTGTGCAGCACTTCTGGGGGGT GCTTAAGTCCCGCGGTCTGCTCTACAGGGCGTCTATGAAGGTTGGTATTGCGCTTCCGAC GAGTGCTTCCTGCCTGAGGCCAAGGTCACCCAGCAGCCGGGCCCATCGGNNGGATTCGTT TCCTGTATCTCTCGAGAGCGGGCATCCAGTCNTCTGGACCAAGGAAAGAAACTACATTNT CAGGCTNNTCCAGTTNCGGAAGCCACTNCAGCGGTGGGCTGCGGGCAACCCCTCAGCGAT CACCCNCGAACCATTTCATCACGTAGTNCTTTCAGTGGCTGGACGAAGAGCTGNCCGACC TGTCCGTGTCTCGCAGAAGTAGCCACTTGACTG >OriGene 3' read for NM_138395 unedited
CGGAACTATCTATGGNACCGCGGCCGCATTCTAGGATCGAGTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTACCAACTTTTGAACTTTGATAACTTAAGTTAAAA GAGCAAAGGAAATAATCCGTTAAAATTACCTGAAAGTTGGGTATTAACATTTATAATAAC TTTTACACAATTTTTATATTGGATTAAAAATCCTGATTGATCTTATTAAAACACGAGGTA AATTATGCGGGGGGGGAACAAAATTAAAACTTTTAGAAATATAAAGAAAACATTGCCCTT TTGAACTATTTACAAATTTTTAAAACATACCTGGGACCCAATGTTACTAAAGTTTAAAAT TTTTAACATACCCAGGGCCTTAAGAGTTTTTTTATTTATTATAAAAACAACTTGGAACAT TTACCTATTCCCCTATTAAAACTTTCACAAAGTCAATGCCCTTCTCTAGCGATTCTAAAA AAAACCAGGCTTTTGGTAAACTTGGGGGGGGTTTTTGCTTTCCCTCAAAACAAAGGGGGT GGAAAGGTTTCCCCTTTTTTTAAAAAAACCCCAAAATGTTAAGACCTCCCAACTTTAGAA GCCAAAACCAATTTTTTCTCAACTTTCCAAACCTTTATCTTTTATAAGAAAACAGTGGGC GAAATAGAACCCTCTTCCCGGTGGAGGTGTGGGTGGCCCCACCCCCCCCTAGGGGGGCAT TCAACAAAACCGGGGGGAGCTTTTTGTGGGGAATATTAAATGGGGCGGACCCCATGGGGC AACAAAATACTTTTTCCACGCCACCGCGTGTTAAGGGGTCTAATAAAAACACTTCTTTTT TTTCGCCAAAACGACATGTTTGTTAAAAAAGGCGCCCCTCTAGAACAAAAAGGAGGGGGG GTGCCCCCCTAGCCAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_138395 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_138395.2, NP_612404.1 |
| RefSeq Size | 3043 bp |
| RefSeq ORF | 1782 bp |
| Locus ID | 92935 |
| UniProt ID | Q96GW9 |
| Domains | tRNA-synt_1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Aminoacyl-tRNA biosynthesis, Selenoamino acid metabolism |
| Gene Summary | This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause a Neurodegenerative Phenotype in Flies and a Recessive Ataxia (ARSAL) in Humans
,null,
PLoS Biology
,PubMed ID 22448145
[MARS2]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224966 | MARS2 (Myc-DDK-tagged)-Human methionyl-tRNA synthetase 2, mitochondrial (MARS2), nuclear gene encoding mitochondrial protein |
CNY 4,416.00 |
|
| RC224966L3 | Lenti ORF clone of Human methionyl-tRNA synthetase 2, mitochondrial (MARS2), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224966L4 | Lenti ORF clone of Human methionyl-tRNA synthetase 2, mitochondrial (MARS2), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
|
| RG224966 | MARS2 (tGFP-tagged) - Human methionyl-tRNA synthetase 2, mitochondrial (MARS2), nuclear gene encoding mitochondrial protein |
CNY 6,016.00 |
