Rtel1 (NM_001191857) Rat Tagged ORF Clone
CAT#: RR217571
- TrueORF®
Rtel1 (myc-DDK-tagged) - Rat regulator of telomere elongation helicase 1 (Rtel1)
"NM_001191857" in other vectors (1)
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CNY 12,260.00
CNY 300.00
Specifications
Product Data | |
Type | Rat Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | RGD1306721 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RR217571 representing NM_001191857
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCCAGGGTAGTCCTGAATGGTGTGACAGTGGATTTCCCTTTCCAGCCCTACCCATGCCAGCAGGAAT ATATGACCAAGGTGCTAGAATGTCTCCAGAAGAAAGTGAATGGCATCCTCGAGAGCCCCACTGGCACTGG GAAGACGCTATGCCTCCTCTGCACTACATTGGCCTGGCGGGAACATCTCCGAGATGCCGTTTCTTCCCTA AAGATTGCTGAGAGAGTTCAAGGGGAACTCTTTGCCAGTCGGACCTTGTCATCCTGGAGGAGTGCTGCTG ATGCCAATGGAGACTCAATAGATTGCTACACAGATATCCCAAAGATCATCTATGCTTCTAGAACTCACTC ACAGCTAACTCAGGTCATCGGTGAGCTTCGGAATACTTCCTACCGGCCCAAGGTGTGTGTGCTGGGCTCC CGGGAGCAGCTGTGTATTCATCCCGAAGTGAAGAAGCAAGAGAGTAACCACATGCAGATCAGTTTGTGCC GTAAGAAGGTGGCAAGTCGCTCCTGTCATTTCTACAACAATGTGGAAGAGAAAAGCCTGGAGCAAGAGCT GGCTACCCCCATCTTGGATATTGAGGACCTTGTGAAGAACGGAAGCAAACACAAAGTGTGCCCATACTAC CTCTCTCGAAACCTGAAGCAGCAAGCTGATATCATCTTTATGCCATACAATTACTTGTTGGATGCTAAGA GTCGTAAGGCACACAACATTGACCTGAAGGGAACGGTTGTAATCTTTGATGAAGCTCACAATGTGGAAAA GATATGTGAGGAGTCAGCCTCCTTTGACTTGACTCCCCGAGATGTGGCTTCAGGACTGGAGGTTATCAAC CAGGTTTTGGAGGAGCAAGCCCGGGTGGCTCAGCATGGTGAACTCCAACAGGAGTTCATTATAGACACGT CCAGCTCAGGTCTCAACATGGAGCTGGAAGACATCGCAAAGTTGAAGATGATCCTGCTGCACCTGGAGGA GGCTATTGATGCTGTTCAGCTGCCTGGGGATGACAGAGGAGTCACCAAACCTGGAAGCTACATCTTCGAG CTGTTTGCTGAAGCACAAATAACATTTCAAACCAAAGGCTGCATTTTGGAGTCGCTGGACCAGATAATCC AGCACCTGACAGGACGCACTGGTGTGTTCACCAACACGGCTGGGTTGCAGAAGCTCATGGACATTATCCA GATTGTGTTCAGCGTGGACCCTCTGGAAGGCAGCCCTGGTTCTCAGGTGGGGCTGGGTAGCTCACATTTC TATAAGGTACACATACACCCTGAAACCAGCCACCGGAGAGCAGCTCAGCGGTCAGATGCCTGGAGTACCA CTGCATCCAGGAAACAAGGGAAGGTGCTGAGCTATTGGTGCTTCAGTCCCAGCCACAGCATGCGTGAACT GGTCCAGCAAGGAGTCCGTACCCTTATCCTCACCAGTGGTACACTGGCTCCGCTGTCTTCCTTTGCTCTG GAGATGCAAATTCCATTCCCAGTCTGTCTGGAGAATCCACACATCATTGACAAGAACCAGCTCTGGGTAG GGGTTATCCCCAGAGGACCTGATGGTGTTCAGCTAAGCTCTGCCTATGACAAAAGGTTTTCTGAAGAGTG CTTATCTTCCCTGGGGAAGGCTCTGGGCAACATTGCTCGTGTGGTGCCCCATGGGCTTCTGGTCTTCTTC CCTTCCTACCCTGTCATGGAGAAAAGCCTGGAGTTCTGGCAGGCGCAAGGCATGTCCAAAAAGGTAGAGG CACTGAAGCCTCTATTCGTGGAACCCAGGAACAAAGGCAGCTTCTCAGAGGTCATTGATGCCTACTACCA GCAAGTTGCCTCCCCTGGGTCTAATGGGGCCACCTTCTTAGCAGTGTGTCGAGGAAAGGCCAGTGAAGGG CTGGACTTCTCAGACATGAATGGTCGTGGTGTGATTGTCACGGGCCTCCCATATCCCCCACGCATGGATC CCCGTGTTATCCTCAAGATGCAGTTCTTGGATGAGATGAAAGGCCGGAGTAGGGTTGGAGGCCAGTGCCT CTCTGGACAGGAATGGTACCAGCAACAAGCATCCAGGGCTGTGAACCAGGCTATTGGGAGGGTTATCCGA CACCGCCATGACTATGGGGCCATCTTCTTATGTGACCACAGGTTTGCCTATGCTGATGCCAGGGCCCATC TGCCCTCCTGGGTGCGCCCCTACCTCAAGGTGTATGACAACTTTGGCCGTGTCATCCGAGATGTGGCCCA GTTCTTCCGTGTTGCTCAGAAAGCTATGCCTTTGCCAGTTCCTCAGGCTGTGACCTCAAGTGTGAGTGAG GGAGAAGCTGCTGTCAAGGAGGCCACATTGTCCAGCCACTCCCTCTCCACCAGGAAAGCCATGAGCTTGG ATGTGCATGTGCCCAGCCTGAGGCGGAGGCCCGTAGGATTACCGACTGCTGGAGACTCCGAGAGCAGCGT ATGTGTGGAGTATGAGCAGCAGACATTTTCTGCCCAGAAGAGACCCATGGGGCTGCTAGCTGCCTTAGAG TACAACGAGCAGAAGGCTGGGGCATCTGAGGAGCAGGCACTCAGCTCCTCCACCCCATCTCTCCGGTGTG AAAAGAGGCTGTCCGTTGAGCAAAGAGGAGGAAAGAAGAAAGTCAGGCTGGTCAACCATCCGGAGGAACC AGTGGCTGGCACACAGGCAGGCAGAGCCAAGATGTTCATGGTGGCCGTGAAGCAAGCACTGAGCCAAGCT AACTTTGACACCTTTACCCAGGCCCTGCAGCACTATAAGAGTTCTGATGACTTTGAAGCCCTAGTGGCCT CTCTCACCTGCCTCTTTGCTGAAGACCCCAAGAAACACACCCTACTTAAAGGTTTCTACCAGTTTGTACG ACCCCACCACAAGCAGCAGTTTGAGGACATCTGCTTCCAGCTAACAGGCCAACGATGTAGCTACCAGCCA GGAAACAGCCTTCCCTTTGGAGAGCAAGCACAGTCAACTGCCAGTAAGCAAGGAAGGAGAGAGCTGGAAT CTAAACTGACCTTGTCTGAAGGTGCAGATAGGCAGCTGGATCCTGGAGAGCACCTGAATCAGGGGTGGCC TCACCTGTCTACCCATCTAACCTCCAAAGGAGACACCAGCAATTGTCCAAAAGTGGGATGTGTGGGAGAA AAACCTGGCCAGCCTGCTGTGAATGACTACCTATCTGACGTCCACAAAGCTCTGGGATCTGCAAGCTGCA ACCAGCTTACGGCAGCTCTGAGGGCATACAAACAGGATGATGACCTGGACAAAGTGCTGGCTGTGGTGGC AGCATTGACCACTGCAAAACCTGAACACTTATCTTTGCTACAGAGATTTGGCATGTTTATACGTCGGCAT CATAAGCCTCGGTTTGTACAGACCTGTGCAGACCTAATGGGCCTACCTACCATAGGCAAGGGCTTGGAGC TCCCATGTCCCAGGGATGAGAGTACAACTGTGCCTTCTGAGCTTACTCATGAGGACATGAAACCAGGGCC CTCGACGTCCAAGAAACCTGAGAAGACCCAGAGTAAGATCTCATCCTTCCTTAGACAGAGGCCAGACCAG AGTGCGAGGTCTGATGATACCATAATGCAGCTTCCTCCCAGACTACCCCCTGAACACACGACGTCTCAGT GGAATTTTGTATGCCCAGCCTGTGCAACTGAGGATACAGTGCTTTTCCAGTGCCCTTCCTGTGACTTCTG CCGCTGCCGGGCCTGCTGGCAACGTCAACTCCAGGCCTCTAGACTGTGTCCAGCTTGTGGTGCTGTTAAC AGGAAGCAGAGCATTGCACAGGTCATCTGGCCGAAGCCCCAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RR217571 representing NM_001191857
Red=Cloning site Green=Tags(s) MPRVVLNGVTVDFPFQPYPCQQEYMTKVLECLQKKVNGILESPTGTGKTLCLLCTTLAWREHLRDAVSSL KIAERVQGELFASRTLSSWRSAADANGDSIDCYTDIPKIIYASRTHSQLTQVIGELRNTSYRPKVCVLGS REQLCIHPEVKKQESNHMQISLCRKKVASRSCHFYNNVEEKSLEQELATPILDIEDLVKNGSKHKVCPYY LSRNLKQQADIIFMPYNYLLDAKSRKAHNIDLKGTVVIFDEAHNVEKICEESASFDLTPRDVASGLEVIN QVLEEQARVAQHGELQQEFIIDTSSSGLNMELEDIAKLKMILLHLEEAIDAVQLPGDDRGVTKPGSYIFE LFAEAQITFQTKGCILESLDQIIQHLTGRTGVFTNTAGLQKLMDIIQIVFSVDPLEGSPGSQVGLGSSHF YKVHIHPETSHRRAAQRSDAWSTTASRKQGKVLSYWCFSPSHSMRELVQQGVRTLILTSGTLAPLSSFAL EMQIPFPVCLENPHIIDKNQLWVGVIPRGPDGVQLSSAYDKRFSEECLSSLGKALGNIARVVPHGLLVFF PSYPVMEKSLEFWQAQGMSKKVEALKPLFVEPRNKGSFSEVIDAYYQQVASPGSNGATFLAVCRGKASEG LDFSDMNGRGVIVTGLPYPPRMDPRVILKMQFLDEMKGRSRVGGQCLSGQEWYQQQASRAVNQAIGRVIR HRHDYGAIFLCDHRFAYADARAHLPSWVRPYLKVYDNFGRVIRDVAQFFRVAQKAMPLPVPQAVTSSVSE GEAAVKEATLSSHSLSTRKAMSLDVHVPSLRRRPVGLPTAGDSESSVCVEYEQQTFSAQKRPMGLLAALE YNEQKAGASEEQALSSSTPSLRCEKRLSVEQRGGKKKVRLVNHPEEPVAGTQAGRAKMFMVAVKQALSQA NFDTFTQALQHYKSSDDFEALVASLTCLFAEDPKKHTLLKGFYQFVRPHHKQQFEDICFQLTGQRCSYQP GNSLPFGEQAQSTASKQGRRELESKLTLSEGADRQLDPGEHLNQGWPHLSTHLTSKGDTSNCPKVGCVGE KPGQPAVNDYLSDVHKALGSASCNQLTAALRAYKQDDDLDKVLAVVAALTTAKPEHLSLLQRFGMFIRRH HKPRFVQTCADLMGLPTIGKGLELPCPRDESTTVPSELTHEDMKPGPSTSKKPEKTQSKISSFLRQRPDQ SARSDDTIMQLPPRLPPEHTTSQWNFVCPACATEDTVLFQCPSCDFCRCRACWQRQLQASRLCPACGAVN RKQSIAQVIWPKPQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001191857 |
ORF Size | 3822 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001191857.1, NP_001178786.1 |
RefSeq Size | 4237 bp |
RefSeq ORF | 3825 bp |
Locus ID | 362288 |
UniProt ID | Q5RJZ1 |
MW | 141.8 kDa |
Gene Summary | ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RN217571 | Rtel1 (untagged) - Rat regulator of telomere elongation helicase 1 (Rtel1) |
CNY 12,260.00 |