Arhgap24 (NM_001012032) Rat Untagged Clone
CAT#: RN211687
Arhgap24 (untagged ORF) - Rat Rho GTPase activating protein 24 (Arhgap24), (10 ug)
CNY 8,460.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Rat Untagged Clone |
Tag | Tag Free |
Synonyms | DR-NR#2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RN211687 representing NM_001012032
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCTGAAGACCGAAATTCGGGGGGACGCCCTTCAGGTGCCTTAGCATCAACTCCTTTCATCCCCAAAA CTACATACAGAAGAATCAAACGGTGCTTTAGTTTCCGGAAAGGTATTTTTGGACAGAAACTGGAGGACAC GGTCCGATATGAGAAGAGATACGGGAACCGGCTGGCGCCCATGCTGGTGGAGCAGTGCGTGGACTTCATC CGACAGCGGGGGCTGAAGGAAGAGGGCCTCTTCCGACTGCCCGGCCAGGCAAACCTTGTCAAGGAGCTCC AGGATGCATTCGACTGTGGAGAGAAGCCCTCCTTCGACAGCAACACAGACGTCCACACTGTGGCATCCCT CCTGAAACTGTATCTCCGAGAACTTCCAGAGCCGGTCGTTCCTTACGCAAAGTACGAAGACTTTTTGTCC TGTGCCACGCTGCTCAGCAAGGAGGAAGAAGCTGGCGTGAAGGAGCTAACGAAACAAGTGAAGAGTTTGC CAGTGGTTAACTACAACCTCCTGAAGTACATTTGCAGGTTCCTGGATGAAGTGCAGTCCTATTCGGGAGT TAACAAGATGAGCGCACAGAACTTGGCAACTGTCTTCGGTCCTAACATCCTGCGCCCAAAGGTGGAAGAT CCTTTAACCATCATGGAGGGCACTGTGGTGGTCCAGCAGTTAATGTCAGTGATGATCAGCAAACATGATC GCCTCTTCCCCAAAGACACAGAGCCACAAAGCAAGCCCCAAGAAGGACCGAACAGCAATAACAACGATGG TCATAAGAAAGTCACCATGGGTCAGTTACAGAACAAAGAAAACAACAATACCAAGGAGAGTCCGGTCAGA CGGTGCTCTTGGGACAAGCCTGAATCCCCCCAGAGAAGCAGCATGGACAACGGATCCCCCACAGCTCTAT CAGGGAGCAAAACCAACAGCCCACGGAACAGTATCCACAAGCTGGATGTCTCCAGGAGCCCGCCTCTCAC GGTCAAAAAGAACCCAGCCTTCAATAAGGGCAGCGGGATCGTCACCAATGGGTCCTTCAGCAGCAGCAAT GCAGAAGGTGTGGAGAAAACCCAAACCACTCCTAATGGGAGTTTACAAGCCAGAAGGACCTCTTCCCTGA AGAGTTCTGGTACCAAAATGGGTACTCATAGCGTACAGAATGGCACCGTGCGCATGGGTATTTTGAACAC TGACACACTAGGGAATTCCTTGAATGGCCGGAGCATGAGTTGGCTGCCCAATGGCTACGTGACCCTGAGA GATAACAAGCAGAAGGAGCCCGCGGGAGAGTCAGGCCAGCACAACAGACTCTCCACCTACGACAACGTCC ACCAGCAGTTCTCCTTGATGAACCTCGACGACAAGCACAGCGTGGACAGTGCCACGTGGTCCACCTCCTC CTGTGAAATCTCCCTCCCCGAGAACTCCAACTCCTGCCGCTCCTCTACCACTACGTGCCCGGAGCAAGAC TTCTACGGCGGGAACTTTGAGGACCCTGTTTTAGACGGCCCGCCTCAGGATGACCTTTCTCATCCTGGGG ACTATGAGAACAAAAGCGACCGCAGGAGCGTGGGGGGCCGAAGCAGCCGTGCCACGAGCAGCAGCGACAA CAGCGAGACGTTCGTCGGTAACACCAGCAGCAACCACAGTGCACTTCACAGTTTAGTCTCCAGCCTGAAG CAGGAGATGACCAAACAGAAGATCGAGTATGAGTCCAGGATAAAAAGCTTAGAACAGCGGAACTTGACTT TGGAAACGGAAATGCTGAACCTCCATGACGAACTGGATCAAGAGAGGAAAAAGTTCACCATGATAGAAAT CAAGATGAGAAACGCCGAGCGCGCGAAAGAGGATGCTGAGAAGAGGAACGACATGCTCCAGAAGGAAATG GAGCAGTTCTTCTCCACATTCGGAGACCTGACGGTGGAACCCAGGAGAAGCGAGAGGGGAAACACAATCT GGATCCAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001012032 |
Insert Size | 1971 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001012032.1, NP_001012032.1 |
RefSeq Size | 2728 bp |
RefSeq ORF | 1971 bp |
Locus ID | 305156 |
UniProt ID | Q5U2Z7 |
Gene Summary | Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RR211687 | Arhgap24 (Myc-DDK-tagged ORF) - Rat Rho GTPase activating protein 24 (Arhgap24), (10 ug) |
CNY 8,460.00 |
|
RR211687L3 | Lenti ORF clone of Arhgap24 (Myc-DDK-tagged ORF) - Rat Rho GTPase activating protein 24 (Arhgap24), (10 ug) |
CNY 10,260.00 |
|
RR211687L4 | Lenti ORF clone of Arhgap24 (mGFP-tagged ORF) - Rat Rho GTPase activating protein 24 (Arhgap24), (10 ug) |
CNY 11,210.00 |
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