Wrap53 (NM_001007610) Rat Untagged Clone

CAT#: RN211362

Wrap53 (untagged ORF) - Rat WD repeat domain 79 (Wdr79), (10 ug)



  "NM_001007610" in other vectors (3)

CNY 6,840.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Rat Untagged Clone
Tag Tag Free
Synonyms Wdr79
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>RN211362 representing NM_001007610
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGAAGACGTCGGAGGAGCTACGCCTAGCTCCGGATAGCCTCCCTTCTGACCTGGTCCCAGCCCCAGTGC
TCCAAGCTTCCCCCGCGGACAAAAATACAGACTCTGAACCGGTGCCTCCGCCATGCGGTGGAGATGACCA
ACTCCAGGTAGCCACAGATGCCGTGGCCAGCTCGGTTGTGTCCCAGGAGCTTCAACAAGGGGACTCAGCT
CCTCTGGAAGTAGAATTTAATATTTCCAGTGAGTTGAGTCCTCGAATCGAGGAGCAAGAAGTTCCTGAAA
ATGCCAGCCTTCCTGTAGAAGAAACGAATCGGCCCGAGTTGGAGTCAGGGGAAGCCATGGAAGGTGTGTC
TGAGGAACCCGCTGCAGTGGATGAGGGGGACATCTTTTGGAGCTACAGCTTCTCTCAGGTACCCCAATAC
CTCAGTGGCTCCTGGTCCGAGTTCAGCACCCGCTCCGAGAACTTCTTGAAAGGTTGCAAGTGGGCCCCTG
ACGGTTCCTGTATCTTGACCAATAGTGCTGACAATGTCCTACGGATTTACAACCTGCCCCCAGAACTGTA
CAGTGAAAGCGAGCAGGTGGATTATGCCGAAATGGTTCCTGTCCTGCGAATGGTAGAGGGTGACACCATC
TATGATTACTGCTGGTATTCTCTGATGTCCTCCACCCAGCCAGACACCTCCTATGTGGCCAGCAGCAGCC
GGGAGAACCCAATTCACATCTGGGATGCATTCACTGGAGAACTCCGGGCTTCCTTTCGCGCTTACAACCA
CCTGGACGAGTTGACAGCGGCCCACTCACTCTGTTTCTCCCCGGATGGTTCCCAACTCTTTTGTGGCTTC
AACCGGACTGTGCGTGTCTTTTCCACATCCAGGCCTGGCAGAGACTGTGAGGTGCGAACCACATTTGCCA
AAAAGCAGGGCCAGAGTGGCATCATCTCCTGTCTAGCCTTTAGTCCAGCCCAGCCCCTCTATGCCTGTGG
CTCCTATGGCCGCACCCTGGGCCTGTATGCCTGGGATGATGGTTCACCTCTTGCCTTGCTGGGGGGCCAT
CAAGGAGGTATCACCCACCTTTGCTTTCACCCTGATGGCAACCTCTTCTTCTCAGGAGCCCGAAAGGATG
CTGAACTTCTGTGCTGGGATCTCCGGCAGCCGGGCCACCTCCTGTGGTCTCTGAGTCGGGAAGTGACCAC
CAATCAGCGCATCTACTTTGATCTGGACCCGAGCGGGCAGTTCCTAGTGAGTGGCAACACCAGTGGAGTT
GTCTCCGTGTGGGACATCAGTGGAGCGTTCAGTGACTGCAAGCAGCTGGAGCCAGTGATGACTTTTCTGC
CCCAGGACGACTGCACCAATGGAGTCAGCCTTCACCCTACCTTGCCTCTGCTGGCCACTGCTTCTGGCCA
GCGCATGTTTCCAGAGCCCACCAATAGCGGGGATGAAGGTGAGCCGGAGCTGGACCTTCCCCTGCTCTCC
CTGCGCCACGCCCATCCTGAATGTCAGCTACAGCTCTGGTGGTGTGGAGGGGGACCTGACCCCAGTAACC
CTGATGAGGACCAGGATGAGAAGGGACAAGGAAGGACAGAGGCTGTCGGAATGAGTTAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001007610
Insert Size 1599 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001007610.1, NP_001007611.1
RefSeq Size 1782 bp
RefSeq ORF 1599 bp
Locus ID 287432
UniProt ID Q5XII5
Gene Summary RNA chaperone that plays a key role in telomere maintenance and RNA localization to Cajal bodies. Specifically recognizes and binds the Cajal body box (CAB box) present in both small Cajal body RNAs (scaRNAs) and telomerase RNA template component (TERC). Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, required to stimulate the catalytic activity of the complex. Acts by specifically binding the CAB box of the TERC RNA and controlling the folding of the CR4/CR5 region of the TERC RNA, a critical step for telomerase activity. In addition, also controls telomerase holoenzyme complex localization to Cajal body. During S phase, required for delivery of TERC to telomeres during S phase and for telomerase activity. In addition to its role in telomere maintenance, also required for Cajal body formation, probably by mediating localization of scaRNAs to Cajal bodies. Also plays a role in DNA repair: phosphorylated by ATM in response to DNA damage and relocalizes to sites of DNA double-strand breaks to promote the repair of DNA double-strand breaks. Acts by recruiting the ubiquitin ligase RNF8 to DNA breaks and promote both homologous recombination (HR) and non-homologous end joining (NHEJ).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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