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Mad2l2 (NM_001012106) Rat Untagged Clone
CAT＃: RN210119
Mad2l2 (untagged ORF) - Rat MAD2 mitotic arrest deficient-like 2 (yeast) (Mad2l2), (10 ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN210119 representing NM_001012106
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACCACCCTCACGCGCCAAGACCTCAACTTCGGCCAAGTGGTGGCCGACGTGCTCTCCGAGTTCCTGG AGGTGGCCGTGCACTTGATCCTCTATGTGCGCGAGGTCTACCCGGTGGGCATCTTTCAGAAGCGCAAGAA GTACAACGTGCCGGTTCAGATGTCCTGCCACCCAGAGCTGAACCAGTACATCCAGGACACACTTCACTGC GTCAAACCACTCCTGGAGAAGAACGATGTGGAGAAGGTGGTGGTGGTGATTTTGGATAAGGAACACCGCC CAGTGGAGAAGTTTGTCTTTGAGATCACTCAGCCACCCTTGCTGTCCATCAAGCTAGGTGGCCTCAAACA GACCGTTTCTCTAACTGTCTTGGGGTCCTGGAGGTATGCAGACTTGAGCGGTACCCTGGGTGTCCTCTCG ACAGCTGAATATTTGAGTGACCTAAAGGGACCTTTGTACCCTACCTCTATTCAGTCAGTTCAGACTCCCT CCTGTCTCATGTGGAGCAGCTGCTTCGAGCCTTCATTCTTAAGATTAGTGTGTGTGACGCTGTCCTCGAC CATAATCCTCCAGGCTGCACGTTTACAGTTCTCGTGCACACAAGAGAAGCTGCCACTCGGAACATGGAGA AGATACAGGTCATCAAGGACTTCCCCTGGATCCTGGCAGATGAGCAAGATGTCCACATGCATGATCCCCG GTTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001012106 |
| Insert Size | 705 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001012106.1, NP_001012106.1 |
| RefSeq Size | 1188 bp |
| RefSeq ORF | 705 bp |
| Locus ID | 313702 |
| UniProt ID | D3Z8D9 |
| Gene Summary | Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR210119 | Mad2l2 (Myc-DDK-tagged ORF) - Rat MAD2 mitotic arrest deficient-like 2 (yeast) (Mad2l2), (10 ug) |
CNY 3,990.00 |
|
| RR210119L3 | Lenti ORF clone of Mad2l2 (Myc-DDK-tagged ORF) - Rat MAD2 mitotic arrest deficient-like 2 (yeast) (Mad2l2), (10 ug) |
CNY 6,080.00 |
|
| RR210119L4 | Lenti ORF clone of Mad2l2 (mGFP-tagged ORF) - Rat MAD2 mitotic arrest deficient-like 2 (yeast) (Mad2l2), (10 ug) |
CNY 6,650.00 |
