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Creb3l1 (NM_001005562) Rat Untagged Clone
CAT＃: RN207304
Creb3l1 (untagged ORF) - Rat cAMP responsive element binding protein 3-like 1 (Creb3l1), (10 ug)
CNY 6,650.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | Oasis |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN207304 representing NM_001005562
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACGCCGTCTTGGAACCTTTCCCGGCCGACAGGCTGTTCCCGGGATCCAGCTTCCTGGACTTGGGAG ACCTGAATGAGTCGGATTTCCTCAACAATGCGCACTTCCCGGAGCACCTGGACCACTTTGTGGAGAACAT GGAGGACTTCTCCAATGACCTGTTCAGCAGCTTCTTTGATGACCCTGTGCTGGATGAGAAGAGCCCTCTG CTGGACATGGAACTGGATTCCCCTGCTCCAGGCATCCAGGCTGAGCACAGCTACTCCCTGAGTGGGGATT CTGCACCCCAGAGCCCCCTTGTGCCTGTCAAAATGGAGGATACCACCCAAGATATGGAACACGGAGCATG GGCACTGGGAAACAAACTGTGCTCCATTATGGTGAAGCAGGAGCAGAGCCCGGAGCTTCCGGTTGACCCC CTGGCTGCCTCCTCCGCCATGGCTGCTGCTACCATGGCCACCCCACCACTGCTGGGCCTCAGCCCCATCT CCAGGCTGCCCATCCCTCACCAGGCCCCAGGAGAAATGACTCAGCTGCCAGTGATCAAAGCAGAGCCCCC GGAAATGAGCCAGTTTCTCAAAGTGACACAAGAGGACCTCGTACAGATGCCTCCAACACCCCCCAGCAGC CATGGCAGTGACAGTGACGGCTCCCAGAGTCCCCGCTCTCTTCCCCCCTCCAGCCCTGTCCGGCCCATGG CCCGCTCCTCCACGGCCATTTCCACCTCTCCGCTCCTCACTGCCCCTCACAAACTGCAGGGGACATCAGG GCCACTGCTCTTGACAGAAGAGGAGAAGCGAACTTTGATCGCCGAGGGTTATCCCATCCCCACCAAACTC CCCCTCACCAAGGCTGAGGAGAAGGCCCTGAAGAGAGTGCGCAGGAAAATTAAGAACAAGATCTCTGCCC AGGAGAGCCGCCGCAAAAAGAAGGAGTATGTGGAGTGTCTAGAGAAGAAGGTGGAGACATATACATCAGA GAACAATGAACTGTGGAAGAAGGTGGAAACCCTAGAGACTGCCAACAGGACCCTGCTCCAGCAGCTGCAG AAACTCCAGACTCTGGTCACCAGCAAGATCTCCAGACCTTACAAGATGGCGGCCACACAGACTGGCACTT GCCTCATGGTGGCAGCCTTGTGCTTTGTTCTGGTGCTGGGCTCACTTGCGCCCTGCCTTCCTGCATTCTC TTCTGGCTCAAAGACTGTGAAAGAAGACCCCGTCGCAGCTGACAGTGTCTACGCAGCCAGTCAGATGCCT TCCCGAAGCCTGCTGTTTTATGATGATGGGGCAGGCTCCTGGGAAGATGGCCACCGAGGTGCTCTACTGC CTGTGGAGCCCCCAGAAGGCTGGGAGCTCAAACCCGGGGGACCAGCAGAGCCGAGGCCCCAGGACCACCT CCGACATGACCATGCGGACAGCATCCACGAGACAACCAAGTACTTGAGAGAGACCTGGCCAGAGGATACC GAGGACAATGGCGCCAGCCCCAATTTCTCCCACCCCAAGGAGTGGTTCCACGACAGGGATCTGGGCCCCA ACACCACCATCAAACTCTCCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001005562 |
| Insert Size | 1563 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001005562.1, NP_001005562.1 |
| RefSeq Size | 2672 bp |
| RefSeq ORF | 1563 bp |
| Locus ID | 362165 |
| UniProt ID | Q66HA2 |
| Gene Summary | Transcription factor involved in unfolded protein response (UPR). Binds the DNA consensus sequence 5'-GTGXGCXGC-3' (By similarity). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in bone formation through the transcription of COL1A1, and possibly COL1A2, and the secretion of bone matrix proteins. Directly binds to the UPR element (UPRE)-like sequence in an osteoblast-specific COL1A1 promoter region and induces its transcription. Does not regulate COL1A1 in other tissues, such as skin (By similarity). Required to protect astrocytes from ER stress-induced cell death. In astrocytes, binds to the cAMP response element (CRE) of the BiP/HSPA5 promoter and participate in its transcriptional activation (By similarity). Required for TGFB1 to activate genes involved in the assembly of collagen extracellular matrix (By similarity).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR207304 | Creb3l1 (Myc-DDK-tagged ORF) - Rat cAMP responsive element binding protein 3-like 1 (Creb3l1), (10 ug) |
CNY 6,650.00 |
|
| RR207304L3 | Lenti ORF clone of Creb3l1 (Myc-DDK-tagged ORF) - Rat cAMP responsive element binding protein 3-like 1 (Creb3l1), (10 ug) |
CNY 8,650.00 |
|
| RR207304L4 | Lenti ORF clone of Creb3l1 (mGFP-tagged ORF) - Rat cAMP responsive element binding protein 3-like 1 (Creb3l1), (10 ug) |
CNY 9,310.00 |
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