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Hexim1 (NM_001025136) Rat Untagged Clone
CAT＃: RN205491
Hexim1 (untagged ORF) - Rat hexamethylene bis-acetamide inducible 1 (Hexim1), (10 ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | Clp-1; Clp1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN205491 representing NM_001025136
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCTGAGCCACTCTTGTCAGAACATCAACACCAGCCTCAAACTAGCAACTGTACAGGTGCTGCTGTTG TCCATGAGGAGCAGAACTCTGAGCGCCCCCCAAGCGCGGAGGAACGGGTGCCTAAGGAGGACAGTAGGTG GCAATCGAGAGCGTCCTTGCAGTCGGGTAGCCGTCCAGGGCAGGAGGGAGACGGGGGCCTGAAGCACCAG CTGCCCCCATTGCAGACGAATGCCTGTCCAGAATTGAGCTGCTTGGAAAAGGGCGAGAAGGGCCAGAATG GGGAGGACTTATCCACTGGCGGTGCCTCGCCTTCGGCGGAGGGGGAGCCGATGTCAGAGTCCCTCGTGCA ACCAGGTCATGACTCGGAGGCTACTAAGCTGGAGGCTCCTGTCGCTGGAGTAGAGGAGCCATGGGGACAG CAACAGAGACAGCTGGGCAAGAAAAAACACCGGAGACGCCCCTCCAAGAAGAAGCGACATTGGAAGCCCT ATTACAAGCTGACTTGGGAGGAGAAGAAAAAGTTCGACGAGAAGCAAAGCCTGCGAGCTTCGCGAGTTCG AGCCGAGATGTTCGCCAAGGGCCAGCCGGTTGCGCCCTATAACACCACGCAGTTCCTCATGGATGACCAT GATCAGGAGGAGCCTGATCTCAAAACCGGCCTTTACCCTAAGCGGGCAGCCGCCAAATCCGACGACACCA GCGATGAGGATTTCGTGGAAGAAGCTGGTGAGGAAGACGGAGGCAGCGATGGCATGGGAGGGGACGGCAG CGAGTTTCTGCAGCGGGACTTTTCCGAGACTTACGAGCGGTACCACGCCGAGAGCCTGCAGAACATGAGC AAGCAGGAGCTCATCAAAGAGTACCTGGAGCTGGAGAAGTGCCTCTCCCGCAAGGAGGACGAAAATAACC GGCTGCGGTTGGAAAGCAAGCGGTTGGGTGGCGTCGATGCGCGAGTGCGGGAGCTGGAGCTAGAGCTGGA CCGACTGCGCGCCGAGAACCGCCAGCTGCTGACCGAAAACGAACTGCACCGGCAGCAGGAGCGAGCGCCT CCTTCCAAGTTCGGCGACTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001025136 |
| Insert Size | 1071 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001025136.1, NP_001020307.1 |
| RefSeq Size | 2143 bp |
| RefSeq ORF | 1071 bp |
| Locus ID | 498008 |
| UniProt ID | Q5M9G1 |
| Gene Summary | Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR205491 | Hexim1 (Myc-DDK-tagged ORF) - Rat hexamethylene bis-acetamide inducible 1 (Hexim1), (10 ug) |
CNY 3,990.00 |
|
| RR205491L3 | Lenti ORF clone of Hexim1 (Myc-DDK-tagged ORF) - Rat hexamethylene bis-acetamide inducible 1 (Hexim1), (10 ug) |
CNY 6,080.00 |
|
| RR205491L4 | Lenti ORF clone of Hexim1 (mGFP-tagged ORF) - Rat hexamethylene bis-acetamide inducible 1 (Hexim1), (10 ug) |
CNY 6,650.00 |
