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Oas3 (NM_001009493) Rat Untagged Clone
CAT＃: RN204624
Oas3 (untagged ORF) - Rat 2 ' -5 ' -oligoadenylate synthetase 3 (Oas3), (10 ug)
CNY 18,340.00
货期*
7周
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN204624 representing NM_001009493
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACCTGTACCACACGCCAGCCGGAGCTCTGGACAAGCTGGTGGCCCACAGCCTGCACCCAGCCCCTG AGTTCACAGCGGCTGTGCGGCGTGCTCTGGGGTCCCTGGACAACGTCCTAAGGAAGAACGGAGCCGGAGG GTTACAGAGACCAAGGGTGATAAGGATCATCAAGGGAGGAGCCCATGCTCGAGGCACAGCTCTCAGAGGT GGCACTGATGTCGAACTCGTCATCTTCCTCGACTGCCTCCGGAGCTTTGGCGACCAGAAGACCTGTCACA CAGAGATCCTGGGCGCCATACAAGCATTGCTGGAGTCCTGGGGGTGCAACCCTGGGCCTGGCCTGACTTT TGAGTTTTCTGGGCCAAAGGCGTCTGGCATCTTACAGTTTCGCCTGGCATCGGTGGACCAAGAAAACTGG ATAGATGTTAGCCTGGTGCCTGCCTTCGATGCCCTAGGACAGCTCCACTCTGAAGTCAAGCCAACACCCA ATGTGTACTCCTCCCTCCTCAGCAGCCACTGCCAGGCTGGGGAACACTCAGCCTGCTTCACAGAGCTCCG GAAGAACTTTGTGAATATCCGCCCAGTCAAACTTAAGAACTTAATCCTGCTGGTCAAACACTGGTACCGC CAGGTGCAGACACAGGTTGTGAGAGCCACACTGCCCCCTAGCTACGCGCTGGAGCTGCTCACCATCTTTG CCTGGGAGCAGGGCTGTAGGAAGGATGCCTTCAGCCTGGCCCAAGGGCTCCGGACTGTCCTGGCCTTGAT CCAACGCAACAAGCATCTCTGCATTTTCTGGACGGAAAACTACGGCTTCGAAGACCCTGCAGTTGGGGAG TTCTTGCGAAGGCAGCTTAAGAGACCCAGGCCCGTGATCCTGGATCCAGCTGACCCAACATGGGACTTGG GCAATGGGACAGCCTGGTGCTGGGATGTGCTTGCCAAGGAGGCTGAATACAGCTTTAACCAGCAGTGCTT CAAGGAGGCCTCAGGAGCCCTTGTGCAACCTTGGGAGGGGCCGGGCCTTCCATGTGCTGGGATCTTGGAT TTGGGTCACCCTATCCAACAAGGAGCTAAGCATGCCCTTGAAGACAACAATGGCCACCTTGCTGTTCAGC CAATGAAAGAGAGCCTACAACCATCAAATCCAGCCCGAGGACTCCCAGAAACAGCCACCAAGATCTCCGC TATGCCAGACCCAACGGTCACTGAAACCCACAAGAGCCTCAAAAAATCAGTGCACCCAAAGACTGTCAGT GAAACAGTGGTGAATCCCTCAAGTCATGTTTGGATCACCCAGAGTACAGCATCCTCAAACACGCCTCCGG GCCACTCTAGTATGTCCACCGCTGGGTCACAGATGGGCCCAGATCTGTCACAGATCCCCAGCAAGGAGCT GGACTCCTTCATCCAGGACCACCTCAGGCCGAGTTCCCAGTTCCAGCAGCAGGTGAGGCAGGCCATCGAC ACCATCCTGTGCTGCCTCCGGGAGAAGTGTGTAGACAAAGTCTTGAGAGTCAGCAAGGGTGGCTCTTTTG GCCGTGGCACAGACCTCAGGGGCAAATGTGATGTGGAGCTTGTCATCTTTTATAAAACTCTCGGGGACTT CAAGGGCCAGAACTCACACCAGACAGAGATCCTGTGTGACATGCAGGCCCAGCTGCAGCGCTGGTGTCAG AACCCAGCACCTGGACTGAGCCTCCAGTTTATTGAACAGAAGTCCAATGCTCTGCATCTTCAGCTGGTGC CCACCAACCTCAGCAACCGGGTAGACCTCAGTGTGCTGCCCGCTTTTGATGCAGTGGGGCCGCTGAAGTC CGGCGCCAAACCTCTACCCGAGACGTACTCCTCCCTCCTCAGCAGCGGCTGCCAGGCTGGGGAGCATGCA GCCTGCTTCGCAGAGCTCCGAAGGAACTTCATAAACACTCGCCCTGCCAAACTTAGGAGCCTGATGCTAC TGGTCAAACACTGGTACCGCCAGGTTGCCGCTCGATTTGAAGGAGGAGAGACAGCAGGTGCTGCTCTGCC CCCAGCCTATGCCCTGGAGCTCCTGACAGTCTTTGCCTGGGAACAAGGCTGCGGAGAACAAAAGTTTAGC ATGGCTGAAGGCCTGCGGACTGTCCTGAGGCTGGTCCAGCAGCACCAGTCACTCTGTATCTACTGGACAG TCAACTACAGTGTGCAGGACCCAGCCATCAGAGCACACCTTCTCCGCCAGCTTCGGAAAGCCAGGCCTCT AATCCTAGACCCTGCAGATCCCACCTGGAACATGGACCAGGGCAACTGGAAGTTGCTGGCTCAGGAGGCG GCTGCCCTGGAGTCACAAGTCTGCCTTCAGAGTAGGGATGGGAATCTGGTGCCACCATGGGATGTTATGC CAGCCCTCCTTCACCAGACCCCGGCTCAGAACCTGGACAAGTTCATCTGTGAATTCCTCCAGCCTGACCG CCATTTCCTGACTCAGGTGAAGAGAGCAGTGGACACCATATGTTCCTTCCTGAAAGAAAACTGCTTCCGG AATTCTACCATCAAGGTGCTCAAGGTGGTCAAGGGTGGGTCTTCTGCCAAAGGCACTGCTCTACAAGGGC GCTCGGATGCTGACCTGGTGGTGTTCCTCAGCTGCTTCCGCCAGTTCTCTGAACAAGGCAGCCATCGGGC AGAGATCATCGCGGAGATCCAGGCTCAGCTGGAGGCGTGTCAGCAGAAGCAGAGGTTCGATGTCAAGTTT GAGATCTCCAAGAGGAAGAACCCCCGAGTTCTCAGCTTCACGCTGACATCCAAGACGCTGCTAGGCCAGA GCGTGGACTTCGATGTGCTGCCAGCCTTCGATGCTCTTGGTCAGCTGAAGTCCGGCTCTCGGCCAGATCC CCGGGTCTACACGGACCTCATCCAGAGCTACAGTAATGCAGGAGAGTTCTCTACCTGCTTCACGGAGCTG CAGCGGGACTTCATTAGCTCCCGTCCCACCAAACTCAAGAGTCTGATCCGTCTGGTGAAACACTGGTACC AACAGTGTAACAAGACAGTCAAGGGGAAGGGTTCCTTGCCCCCCCAGCACGGGCTGGAGCTCCTGACTGT GTACGCCTGGGAGCGAGGCAGCCAGAACCCCCAGTTCAACATGGCGGAGGGCTTCCGCACAGTTCTGGAG CTGATTGGCCAGTACCGTCAGCTGTGCGTCTATTGGACCATCAACTACGGTGCAGAAGACGAGACCATCG GAGACTTCCTGAAGATGCAGCTTCAGAAGCCCAGGCCTGTCATCCTGGACCCAGCTGACCCGACAGGCAA CCTAGGCCACAATGCCCGCTGGGACCTGCTTGCCAAGGAGGCTGCAGCATACACATCTGCCCTGTGCTGC ATGGACAAGGACGGCAACCCCATCAAGCCATGGCCAGTAAAGGCCGCTGTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001009493 |
| Insert Size | 3414 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001009493.1, NP_001009493.1 |
| RefSeq Size | 4015 bp |
| RefSeq ORF | 3414 bp |
| Locus ID | 494202 |
| UniProt ID | Q5MYT7 |
| Gene Summary | Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR204624 | Oas3 (Myc-DDK-tagged ORF) - Rat 2 ' -5 ' -oligoadenylate synthetase 3 (Oas3), (10 ug) |
CNY 18,340.00 |
|
| RR204624L3 | Lenti ORF clone of Oas3 (Myc-DDK-tagged ORF) - Rat 2 ' -5 ' -oligoadenylate synthetase 3 (Oas3), (10 ug) |
CNY 19,760.00 |
|
| RR204624L4 | Lenti ORF clone of Oas3 (mGFP-tagged ORF) - Rat 2 ' -5 ' -oligoadenylate synthetase 3 (Oas3), (10 ug) |
CNY 21,760.00 |
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