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Mknk2 (NM_001011985) Rat Untagged Clone
CAT＃: RN204301
Mknk2 (untagged ORF) - Rat MAP kinase-interacting serine/threonine kinase 2 (Mknk2), (10 ug)
CNY 5,990.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN204301 representing NM_001011985
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTGCAGAAGAGAACAGCCGAACTTCAGGGCTTCCACCGTTCGTTCAAGGGGCAGAATCCTTTCGAGT TGGCCTTCACCTTAGACCCCGCCCAGCACGGGGACTCTGACTTCAGCCCGCAGTGTGAAGCCCGACCTGA CATGCCTTCCAGTCAGCCCATCGACATCCCAGACGCCAAGAAGAGAGGCCGCAAAAAGAAGCGCTGTCGG GCTACTGACAGCTTCTCAGGCAGATTTGAAGATGTCTACCAGCTGCAGGAGGATGTGCTGGGGGAAGGGG CCCATGCCCGTGTGCAGACCTGTGTCAATCTCATCACCAACCAGGAATATGCTGTCAAGATCATTGAGAA GCAGCTGGGCCATATCCGCAGCAGGGTGTTCCGGGAGGTGGAGATGCTGTACCAGTGCCAGGGACATAGG AATGTTCTAGAACTGATTGAGTTCTTTGAGGAGGAGGACCGCTTCTACCTGGTGTTTGAAAAGATGCGTG GTGGATCCATCCTGAGCCACATCCACAGAAGGCGCCACTTTAATGAACTGGAGGCCAGCGTGGTGGTACA GGATGTGGCCAGTGCCCTGGACTTCCTGCATAACAAAGGCATCGCCCACAGGGACCTAAAGCCAGAGAAC ATCCTGTGTGAGCACCCCAACCAGGTCTCGCCAGTGAAGATCTGTGACTTCGATCTTGGCAGTGGCATTA AACTCAACGGAGACTGCTCCCCCATCTCCACGCCAGAGCTGCTCACCCCGTGTGGGTCTGCGGAGTACAT GGCACCCGAGGTGGTGGAAGCCTTTAGTGAGGAGGCCAGCATCTATGACAAGCGCTGCGACCTGTGGAGC CTGGGTGTCATCCTGTACATCCTGCTCAGTGGCTACCCGCCCTTCGTAGGCCACTGTGGCAGCGACTGTG GCTGGGACCGCGGGGAGGCCTGCCCTGCCTGCCAGAACATGCTGTTTGAGAGCATCCAGGAAGGGAAGTA CGAGTTCCCCGACAAGGACTGGTCCCACATCTCCTTCGCTGCCAAAGACCTCATCTCCAAGCTGCTGGTG CGAGATGCCAAGCAGAGGCTGAGCGCTGCCCAAGTTCTGCAGCACCCCTGGGTGCAGGGGTGTGCTCCAG AGAACACCTTACCAACACCCTTGGTTCTGCAGAGGAACAGCTGTGCCAAAGACCTCACGTCCTTTGCAGC TGAGGCCATCGCCATGAACCGGCAGCTGGCCCAGTGTGAGGAGGACGCTGGGCAGGACCAGCCTGTGCTC ATCCGAGCTACCTCACGCTGCCTGCAGTTGTCCCCGCCCTCCCAGTCCAAGCTGGCCCAGAGGCGCCAGA GGGCCAGCCTGTCGGCCACCCCTGTGGTCCTCGTAGGGGATCGCGTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001011985 |
| Insert Size | 1380 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001011985.1, NP_001011985.1 |
| RefSeq Size | 3458 bp |
| RefSeq ORF | 1380 bp |
| Locus ID | 299618 |
| UniProt ID | Q5U2N4 |
| Gene Summary | Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. Required for mediating PP2A-inhibition-induced EIF4E phosphorylation. Triggers EIF4E shuttling from cytoplasm to nucleus. Enhances the formation of EIF4F complex in pachytene spermatocytes, thus promoting mRNA translation during spermatogenesis. Displays a high basal kinase activity. Acts as a mediator of the suppressive effects of IFNgamma on hematopoiesis. Negative regulator for signals that control generation of arsenic trioxide As(2)O(3)-dependent apoptosis and anti-leukemic responses. Involved in anti-apoptotic signaling in response to serum withdrawal (By similarity).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR204301 | Mknk2 (Myc-DDK-tagged ORF) - Rat MAP kinase-interacting serine/threonine kinase 2 (Mknk2), (10 ug) |
CNY 5,990.00 |
|
| RR204301L3 | Lenti ORF clone of Mknk2 (Myc-DDK-tagged ORF) - Rat MAP kinase-interacting serine/threonine kinase 2 (Mknk2), (10 ug) |
CNY 7,790.00 |
|
| RR204301L4 | Lenti ORF clone of Mknk2 (mGFP-tagged ORF) - Rat MAP kinase-interacting serine/threonine kinase 2 (Mknk2), (10 ug) |
CNY 8,550.00 |
