United States
Germany
Japan
United Kingdom
China
Numbl (NM_001033888) Rat Untagged Clone
CAT＃: RN204216
Numbl (untagged ORF) - Rat numb homolog (Drosophila)-like (Numbl), (10 ug)
CNY 7,890.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN204216 representing NM_001033888
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCCCGCAGCGCGGCGGCCAGCGGCGGACCCAGGAGACCTGATCAGCATTTGCCCCCAGCCCCCTGTG GGGCCTCGGGGCCCCCTGAAACCTTCAGGACGGAGTCAGACGGGGCGGGCACCATGAACAAGTTACGGCA GAGTCTGCGGCGGAGGAAGCCAGCCTATGTGCCTGAGGCGTCACGCCCACACCAGTGGCAGGCAGATGAG GATGCGGTGCGGAAGGGCACATGCAGCTTCCCCGTTAGGTACCTGGGCCACGTGGAAGTGGAGGAGTCCC GGGGGATGCACGTTTGTGAAGACGCGGTGAAGAAGCTGAAGGCGATGGGCCGGAAGTCCGTGAAGTCTGT CCTGTGGGTGTCGGCTGATGGGCTCCGAGTGGTGGATGACAAGACCAAGGACCTGCTGGTAGACCAGACC ATCGAGAAGGTGTCCTTCTGTGCTCCTGACCGCAACCTGGACAAGGCATTCTCCTACATATGCCGTGATG GCACCACACGCCGCTGGATCTGCCACTGTTTCCTGGCCCTCAAGGACTCTGGTGAGAGGCTGAGCCACGC TGTGGGCTGCGCGTTCGCTGCCTGCCTGGAGAGGAAGCAGCGACGGGAGAAGGAGTGCGGAGTCACCGCC GCCTTCGATGCCAGTCGCACCAGCTTTGCCCGCGAGGGCTCCTTCCGCCTGTCCGGTGGCGGGCGGCCTG CGGAGCGCGAGGCTGGGGACAAGAAGAAAGAAGCAGCAGCTGCTCCTGCTGTGGCTCCTGGCCCTGCCCA GCCTGGGCACGTTTCTCCGACACCGGCCACTACATCCCCTGGTGAGAAGGGAGAGGCGGGTACCCCAGTG GCTGCAGGCACCACTGCTGCTGCCATTCCCCGGCGCCATGCACCTCTGGAACAGCTGGTTCGCCAGGGCT CCTTTCGTGGGTTTCCTGCCCTCAGCCAGAAGAACTCACCTTTCAAACGTCAGCTGAGTCTACGGTTGAA TGAGCTGCCATCCACACTGCAGCGCCGTACAGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCT CCTGGTACTGGTGACAGCGACGGCATCAGTGCCCTGTGTACACAAATCAGCTCGTCTTTCGCCAGTGCCG GAGCACCAGTGCCAGGGCCACCGTCTGCCACCACAGGGACGTCTGCCTGGGGTGAGCCCTCTGTACCTGC TGCAACTGCCTTCCAGCCCGGGCACAAGCGGACACCGTCGGAGGCTGAGCGATGGTTGGAGGAAGTGTCC CAGGTGGCTAAGGCCCAACAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGC AGCAGCAGCAGCAGCAACAACAACAGCAACAAGCCACCTCCGTGCCACCAATGCCCACCATGGCCCCCAC CCTTCAACCCTTCTCCGCCCCAGTGGGGCCCTTTGACACTGCAGCTGCCCAGGTGGCTGTGTTCCTGCCA CCCACACACATGCAGCCTCCATTTGTGCCCGCCTACCCAGGCCTGGGTTACCCACCCATGCCCCGGGTGC CAGTGGTGGGCATCACACCTTCACAGATGGTGGCCAACGCCTTCTGCTCAGCTGCTCAGCTCCAGCCCCA ACCTGCCACACTGCTTGGAAAAGCCGGGGCCTTCCCCCCACCTACCGCACCCAGTGCCCCTGGGGGCCAG GCCCGTCCACGCCCTAATGGGGCTCCCTGGCCCCCAGAGCCAGCGCCTGCCCCTGCCCCTGAGTTGGACC CCTTTGAGGCCCAGTGGGCAGCTTTAGAAGGCAAGCCCGCCGTGGAGAAACCCTCCAACCCCTTCTCTGG TGACTTGCAGAAGACCTTCGAGATTGAACTGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001033888 |
| Insert Size | 1854 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001033888.1, NP_001029060.1 |
| RefSeq Size | 1854 bp |
| RefSeq ORF | 1854 bp |
| Locus ID | 292732 |
| Gene Summary | Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR204216 | Numbl (Myc-DDK-tagged ORF) - Rat numb homolog (Drosophila)-like (Numbl), (10 ug) |
CNY 7,890.00 |
|
| RR204216L3 | Lenti ORF clone of Numbl (Myc-DDK-tagged ORF) - Rat numb homolog (Drosophila)-like (Numbl), (10 ug) |
CNY 9,790.00 |
|
| RR204216L4 | Lenti ORF clone of Numbl (mGFP-tagged ORF) - Rat numb homolog (Drosophila)-like (Numbl), (10 ug) |
CNY 10,640.00 |
