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Sigirr (NM_001024887) Rat Untagged Clone
CAT＃: RN203114
Sigirr (untagged ORF) - Rat single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr), (10 ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | RGD1306732 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN203114 representing NM_001024887
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCAGGTGTCTGTGACAGGGTCCCTAATTTCCTTTCCCCATCTGAAGACCAAGCCCTGGGACCTGCCC TTGGCAGTGCAGTTGCTTTGAATTGCACAGCTTGGGTGTTCTCTAGGCCCCAGTGTCCCCAGCCATCAGT ACAATGGCTAAAAGATGGTCTGGCATTGGGCAATGGAAGCCACTTCAGCCTCCATCAAGACTTCTGGGTC AGTGACAACTTCTCGGAGATTGTGTCCAGTGTTCTGGTGTTCAACTTGACCAAAGCTGAGGACTATGGAA CCTTCACTTGTTCTGCCTGGAACGTCAGCTCCCACTCCTTCACTCTCTGGCGAGCTGGCCCTGCCGGCCA TGTGGCTGCGGTGCTGGCTTCCCTCCTTGTCCTAGTGGTTCTGCTGCTGGTGGCCCTTCTCTATGTTAAG TGTCGTCTGAACGTGCTGCTTTGGTACCAAGACACTTACGGGGAGGTAGAGATGAATGATGGGAAGTTAT ACGATGCGTACGTGTCCTATAGCGACCGCCCAGAGGACCGCAAATTTGTAAATTTTATTCTGAAGCCTCA GTTGGAGCGGCGTCGGGGATACAAGCTCTTCCTAGAGGACCGCGACCTCTTGCCGCGAGCGGAGCCCTCT GCCGACCTTTTGGTGAACCTGAGTCGCTGTCGGCGTCTCATCGTGGTTCTTTCAGATGCCTTCCTCAGAC GTCCCTGGTGTAGCCAGAGCTTCCGGGAGGGACTGTGCCGCCTACTGGAGCTCACCCGCAGACCTATCTT TATCACCTTCGAGGGCCAGAGGCGTGAGCCCATTCACCCTGCTCTCCGTCTCCTGCGCCAGCACCGCCAC CTCGTGACCCTGCTGCTTTGGAAGCCTGGCTCCGTGACACCTTCCTCTGATTTTTGGAAAGAGCTACAGT TGGCACTACCACGGAAGGTGCAATACAGACCCGTGGAGGGAGACCCCCAAACCCGACTTCAGGATGACAA AGATCCCATGCTAATCGTGAGAGGACGTGCTGCCCAGGGCCGGGCCATGGAGTCAGAGCTGGATCCAGAC CCTGAGGGAGACCTGGGTGTCCGTGGACCTGTCTTTGGGGAGCCACCAACTCCACTACACGAAAGCAAGG TCTCCATAGGAGAGGGCCATGCCAGTGAAATGGATGTCTCTGACCTTGGCTCTCGAAACTACAGTGCGCG AACAGACTTCTACTGCCTTGTGTCTGAGGATGACGTGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001024887 |
| Insert Size | 1230 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001024887.1, NP_001020058.1 |
| RefSeq Size | 1634 bp |
| RefSeq ORF | 1230 bp |
| Locus ID | 309106 |
| UniProt ID | Q4V892 |
| Gene Summary | Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR203114 | Sigirr (Myc-DDK-tagged ORF) - Rat single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr), (10 ug) |
CNY 3,990.00 |
|
| RR203114L3 | Lenti ORF clone of Sigirr (Myc-DDK-tagged ORF) - Rat single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr), (10 ug) |
CNY 6,080.00 |
|
| RR203114L4 | Lenti ORF clone of Sigirr (mGFP-tagged ORF) - Rat single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr), (10 ug) |
CNY 6,650.00 |
