Lair1 (NM_001029928) Rat Untagged Clone

CAT#: RN201965

Lair1 (untagged ORF) - Rat leukocyte-associated immunoglobulin-like receptor 1 (Lair1), (10 ug)



  "NM_001029928" in other vectors (3)

CNY 3,990.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Rat Untagged Clone
Tag Tag Free
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>RN201965 representing NM_001029928
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCCACTTCATTCTGTCATCGTGCTGGTGCTTGTACTGTGCCTGGGATGGAAAAGTAACACACAGGAGG
AATCTCTGTCCGATTTCACTATCTGCGCTGAGCCAGGTCCTGTGATTCCTCAAGGGAATTTCATAACCAT
TGTGTGCTCAACCTCTGGTGAATATGACACGGTCCGCCTGGAGAAGGAAGGCAGCACCTTTATGGAAAAG
AAAACAGAGCCTCATGGAAAACAGCATAGATTCCGTATTGGGCCAGTGAATGAAACCATTACTGGATATT
ATAACTGTATCTTTGAAAAAAATTATGTATGGTCTCAACGAAGTAATGATCTGCAGCTAAAAGTGATCAA
AGAAAATGTCACCCAGGGTCTTGCCCCAGGTCCATCAATGACCTCAGATACATCTTGGCTGAAGACGTAC
AGCATTCACATTCTTACTGTGGTCTCTGTGATTTTCCTCCTTTGTCTTTCCCTCTTTCTATTCTGCTTTC
TTAGCCACCGTCAGAAAAAGCAGGGACTTCCAAACAATAAGAGCCAGCATCAGAGGTCACAGGAGAGGCT
CAACCTAGCTACTAATGGCCTGGAGAAGACATCAGACATAGTCATGGATGACAGCCTTTCTGAGGACAGA
CAGACAGAAACTTGGACCCCAGTTGCAGGAGATCTTCAGGAGGTGACATATGCCCAGCTGGACCATGACT
CCCTCACACAAAGGACTGTTAAAGATGTGACCCCACAGAACAGAGTTATCATGGCTGAGTCCAGTACATA
TGCAGCCATCATGAGATGCTGA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001029928
Insert Size 792 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001029928.1, NP_001025099.1
RefSeq Size 854 bp
RefSeq ORF 792 bp
Locus ID 574531
UniProt ID P0C1X9
Gene Summary Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Modulates cytokine production in CD4+ T-cells, down-regulating IL2 and IFNG production while inducing secretion of transforming growth factor beta. Down-regulates also IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion. Inhibits proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells. Inhibits the differentiation of peripheral blood precursors towards dendritic cells (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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