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CENPE (NM_001286734) Human Tagged ORF Clone
CAT＃: RG240253
- TrueORF®
CENPE (tGFP-tagged) - Human centromere protein E, 312kDa (CENPE), transcript variant 2
ORF Plasmid: DDK
"NM_001286734" in other vectors (2)
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CNY 29,830.00
货期*
2周
规格
Product images
经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | CENP-E; KIF10; MCPH13; PPP1R61 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG240253 representing NM_001286734.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGGAGGAAGGAGCCGTGGCCGTCTGCGTGCGAGTGCGGCCGCTGAACAGCAGAGAAGAATCACTT GGAGAAACTGCCCAAGTTTACTGGAAAACTGACAATAATGTCATTTATCAAGTTGATGGAAGTAAATCC TTCAATTTTGATCGTGTCTTTCATGGTAATGAAACTACCAAAAATGTGTATGAAGAAATAGCAGCACCA ATCATCGATTCTGCCATACAAGGCTACAATGGTACTATATTTGCCTATGGACAGACTGCTTCAGGAAAA ACATATACCATGATGGGTTCAGAAGATCATTTGGGAGTTATACCCAGGGCAATTCATGACATTTTCCAA AAAATTAAGAAGTTTCCTGATAGGGAATTTCTCTTACGTGTATCTTACATGGAAATATACAATGAAACC ATTACAGATTTACTCTGTGGCACTCAAAAAATGAAACCTTTAATTATTCGAGAAGATGTCAATAGGAAT GTGTATGTTGCTGATCTCACAGAAGAAGTTGTATATACATCAGAAATGGCTTTGAAATGGATTACAAAG GGAGAAAAGAGCAGGCATTATGGAGAAACAAAAATGAATCAAAGAAGCAGTCGTTCTCATACCATCTTT AGGATGATTTTGGAAAGCAGAGAGAAGGGTGAACCTTCTAATTGTGAAGGATCTGTTAAGGTATCCCAT TTGAATTTGGTTGATCTTGCAGGCAGTGAAAGAGCTGCTCAAACAGGCGCTGCAGGTGTGCGGCTCAAG GAAGGCTGTAATATAAATCGAAGCTTATTTATTTTGGGACAAGTGATCAAGAAACTTAGTGATGGACAA GTTGGTGGTTTCATAAATTATCGAGATAGCAAGTTAACACGAATTCTCCAGAATTCCTTGGGAGGAAAT GCAAAGACACGTATTATCTGCACAATTACTCCAGTATCTTTTGATGAAACACTTACTGCTCTCCAGTTT GCCAGTACTGCTAAATATATGAAGAATACTCCTTATGTTAATGAGGTATCAACTGATGAAGCTCTCCTG AAAAGGTATAGAAAAGAAATAATGGATCTTAAAAAACAATTAGAGGAGGTTTCTTTAGAGACGCGGGCT CAGGCAATGGAAAAAGACCAATTGGCCCAACTTTTGGAAGAAAAAGATTTGCTTCAGAAAGTACAGAAT GAGAAAATTGAAAACTTAACACGGATGCTGGTGACCTCTTCTTCCCTCACGTTGCAACAGGAATTAAAG GCTAAAAGAAAACGAAGAGTTACTTGGTGCCTTGGCAAAATTAACAAAATGAAGAACTCAAACTATGCA GATCAATTTAATATACCAACAAATATAACAACAAAAACACATAAGCTTTCTATAAATTTATTACGAGAA ATTGATGAATCTGTCTGTTCAGAGTCTGATGTTTTCAGTAACACTCTTGATACATTAAGTGAGATAGAA TGGAATCCAGCAACAAAGCTACTAAATCAGGAGAATATAGAAAGTGAGTTGAACTCACTTCGTGCTGAC TATGATAATCTGGTATTAGACTATGAACAACTACGAACAGAAAAAGAAGAAATGGAATTGAAATTAAAA GAAAAGAATGATTTGGATGAATTTGAGGCTCTAGAAAGAAAAACTAAAAAAGATCAAGAGAATGAACTC AGTTCAAAAGTAGAGCTGCTTAGAGAAAAGGAAGACCAGATTAAGAAGCTACAGGAATACATAGACTCT CAAAAGCTAGAAAATATAAAAATGGACTTGTCATACTCATTGGAAAGCATTGAAGACCCAAAACAAATG AAGCAGACTCTGTTTGATGCTGAAACTGTAGCCCTTGATGCCAAGAGAGAATCAGCCTTTCTTAGAAGT GAAAATCTGGAGCTGAAGGAGAAAATGAAAGAACTTGCAACTACATACAAGCAAATGGAAAATGATATT CAGTTATATCAAAGCCAGTTGGAGGCAAAAAAGAAAATGCAAGTTGATCTGGAGAAAGAATTACAATCT GCTTTTAATGAGATAACAAAACTCACCTCCCTTATAGATGGCAAAGTTCCAAAAGATTTGCTCTGTAAT TTGGAATTGGAAGGAAAGATTACTGATCTTCAGAAAGAACTAAATAAAGAAGTTGAAGAAAATGAAGCT TTGCGGGAAGAAGTCATTTTGCTTTCAGAATTGAAATCTTTACCTTCTGAAGTAGAAAGGCTGAGGAAA GAGATACAAGACAAATCTGAAGAGCTCCATATAATAACATCAGAAAAAGATAAATTGTTTTCTGAAGTA GTTCATAAGGAGAGTAGAGTTCAAGGTTTACTTGAAGAAATTGGGAAAACAAAAGATGACCTAGCAACT ACACAGTCGAATTATAAAAGCACTGATCAAGAATTCCAAAATTTCAAAACCCTTCATATGGACTTTGAG CAAAAGTATAAGATGGTCCTTGAGGAGAATGAGAGAATGAATCAGGAAATAGTTAATCTCTCTAAAGAA GCCCAAAAATTTGATTCGAGTTTGGGTGCTTTGAAGACCGAGCTTTCTTACAAGACCCAAGAACTTCAG GAGAAAACACGTGAGGTTCAAGAAAGACTAAATGAGATGGAACAGCTGAAGGAACAATTAGAAAATAGA GATTCTACGCTGCAAACTGTAGAAAGGGAGAAAACACTGATTACTGAGAAACTGCAGCAAACTTTAGAA GAAGTAAAAACTTTAACTCAAGAAAAAGATGATCTAAAACAACTCCAAGAAAGCTTGCAAATTGAGAGG GACCAACTCAAAAGTGATATTCACGATACTGTTAACATGAATATAGATACTCAAGAACAATTACGAAAT GCTCTTGAGTCTCTGAAACAACATCAAGAAACAATTAATACACTAAAATCGAAAATTTCTGAGGAAGTT TCCAGGAATTTGCATATGGAGGAAAATACAGGAGAAACTAAAGATGAATTTCAGCAAAAGATGGTTGGC ATAGATAAAAAACAGGATTTGGAAGCTAAAAATACCCAAACACTAACTGCAGATGTTAAGGATAATGAG ATAATTGAGCAACAAAGGAAGATATTTTCTTTAATACAGGAGAAAAATGAACTCCAACAAATGTTAGAG AGTGTTATAGCAGAAAAGGAACAATTGAAGACTGACCTAAAGGAAAATATTGAAATGACCATTGAAAAC CAGGAAGAATTAAGACTTCTTGGGGATGAACTTAAAAAGCAACAAGAGATAGTTGCACAAGAAAAGAAC CATGCCATAAAGAAAGAAGGAGAGCTTTCTAGGACCTGTGACAGACTGGCAGAAGTTGAAGAAAAACTA AAGGAAAAGAGCCAGCAACTCCAAGAAAAACAGCAACAACTTCTTAATGTACAAGAAGAGATGAGTGAG ATGCAGAAAAAGATTAATGAAATAGAGAATTTAAAGAATGAATTAAAGAACAAAGAATTGACATTGGAA CATATGGAAACAGAGAGGCTTGAGTTGGCTCAGAAACTTAATGAAAATTATGAGGAAGTGAAATCTATA ACCAAAGAAAGAAAAGTTCTAAAGGAATTACAGAAGTCATTTGAAACAGAGAGAGACCACCTTAGAGGA TATATAAGAGAAATTGAAGCTACAGGCCTACAAACCAAAGAAGAACTAAAAATTGCTCATATTCACCTA AAAGAACACCAAGAAACTATTGATGAACTAAGAAGAAGCGTATCTGAGAAGACAGCTCAAATAATAAAT ACTCAGGACTTAGAAAAATCCCATACCAAATTACAAGAAGAGATCCCAGTGCTTCATGAGGAACAAGAG TTACTGCCTAATGTGAAAGAAGTCAGTGAGACTCAGGAAACAATGAATGAACTGGAGTTATTAACAGAA CAGTCCACAACCAAGGACTCAACAACACTGGCAAGAATAGAAATGGAAAGGCTCAGGTTGAATGAAAAA TTTCAAGAAAGTCAGGAAGAGATAAAATCTCTAACCAAGGAAAGAGACAACCTTAAAACGATAAAAGAA GCCCTTGAAGTTAAACATGACCAGCTGAAAGAACATATTAGAGAAACTTTGGCTAAAATCCAGGAGTCT CAAAGCAAACAAGAACAGTCCTTAAATATGAAAGAAAAAGACAATGAAACTACCAAAATCGTGAGTGAG ATGGAGCAATTCAAACCCAAAGATTCAGCACTACTAAGGATAGAAATAGAAATGCTCGGATTGTCCAAA AGACTTCAAGAAAGTCATGATGAAATGAAATCTGTAGCTAAGGAGAAAGATGACCTACAGAGGCTGCAA GAAGTTCTTCAATCTGAAAGTGACCAGCTCAAAGAAAACATAAAAGAAATTGTAGCTAAACACCTGGAA ACTGAAGAGGAACTTAAAGTTGCTCATTGTTGCCTGAAAGAACAAGAGGAAACTATTAATGAGTTAAGA GTGAATCTTTCAGAGAAGGAAACTGAAATATCAACCATTCAAAAGCAGTTAGAAGCAATCAATGATAAA TTACAGAACAAGATCCAAGAGATTTATGAGAAAGAGGAACAATTTAATATAAAACAAATTAGTGAGGTT CAGGAAAAAGTGAATGAACTGAAACAATTCAAGGAGCATCGCAAAGCCAAGGATTCAGCACTACAAAGT ATAGAAAGTAAGATGCTCGAGTTGACCAACAGACTTCAAGAAAGTCAAGAAGAAATACAAATTATGATT AAGGAAAAAGAGGAAATGAAAAGAGTACAGGAGGCCCTTCAGATAGAGAGAGACCAACTGAAAGAAAAC ACTAAAGAAATTGTAGCTAAAATGAAAGAATCTCAAGAAAAAGAATATCAGTTTCTTAAGATGACAGCT GTCAATGAGACTCAGGAGAAAATGTGTGAAATAGAACACTTGAAGGAGCAATTTGAGACCCAGAAGTTA AACCTGGAAAACATAGAAACGGAGAATATAAGGTTGACTCAGATACTACATGAAAACCTTGAAGAAATG AGATCTGTAACAAAAGAAAGAGATGACCTTAGGAGTGTGGAGGAGACTCTCAAAGTAGAGAGAGACCAG CTCAAGGAAAACCTTAGAGAAACTATAACTAGAGACCTAGAAAAACAAGAGGAGCTAAAAATTGTTCAC ATGCATCTGAAGGAGCACCAAGAAACTATTGATAAACTAAGAGGGATTGTTTCAGAGAAAACAAATGAA ATATCAAATATGCAAAAGGACTTAGAACACTCAAATGATGCCTTAAAAGCACAGGATCTGAAAATACAA GAGGAACTAAGAATTGCTCACATGCATCTGAAAGAGCAGCAGGAAACTATTGACAAACTCAGAGGAATT GTTTCTGAGAAGACAGATAAACTATCAAATATGCAAAAAGATTTAGAAAATTCAAATGCTAAATTACAA GAAAAGATTCAAGAACTTAAGGCAAATGAACATCAACTTATTACGTTAAAAAAAGATGTCAATGAGACA CAGAAAAAAGTGTCTGAAATGGAGCAACTAAAGAAACAAATAAAAGACCAAAGCTTAACTCTGAGTAAA TTAGAAATAGAGAATTTAAATTTGGCTCAGAAACTTCATGAAAACCTTGAAGAAATGAAATCTGTAATG AAAGAAAGAGATAATCTAAGAAGAGTAGAGGAGACACTCAAACTGGAGAGAGACCAACTCAAGGAAAGC CTGCAAGAAACCAAAGCTAGAGATCTGGAAATACAACAGGAACTAAAAACTGCTCGTATGCTATCAAAA GAACACAAAGAAACTGTTGATAAACTTAGAGAAAAAATTTCAGAAAAGACAATTCAAATTTCAGACATT CAAAAGGATTTAGATAAATCAAAAGATGAATTACAGAAAAAGCAGGACCGACAGAACCACCAAGTAAAA CCTGAAAAAAGGTTACTAAGTGATGGACAACAGCACCTTACGGAAAGCCTGAGAGAAAAGTGCTCTAGA ATAAAAGAGCTTTTGAAGAGATACTCAGAGATGGATGATCATTATGAGTGCTTGAATAGATTGTCTCTT GACTTGGAGAAGGAAATTGAATTCCAAAAAGAGCTTTCAATGAGAGTTAAAGCAAACCTCTCACTTCCC TATTTACAAACCAAACACATTGAAAAACTTTTTACTGCAAACCAGAGATGCTCCATGGAATTCCACAGA ATCATGAAGAAACTGAAGTATGTGTTAAGCTATGTTACAAAAATAAAAGAAGAACAACATGAATCCATC AATAAATTTGAAATGGATTTTATTGATGAAGTGGAAAAGCAAAAGGAATTGCTAATTAAAATACAGCAC CTTCAACAAGATTGTGATGTACCATCCAGAGAATTAAGGGATCTCAAATTGAACCAGAATATGGATCTA CATATTGAGGAAATTCTCAAAGATTTCTCAGAAAGTGAGTTCCCTAGCATAAAGACTGAATTTCAACAA GTACTAAGTAATAGGAAAGAAATGACACAGTTTTTGGAAGAGTGGTTAAATACTCGTTTTGATATAGAA AAGCTTAAAAATGGCATCCAGAAAGAAAATGATAGGATTTGTCAAGTGAATAACTTCTTTAATAACAGA ATAATTGCCATAATGAATGAATCAACAGAGTTTGAGGAAAGAAGTGCTACCATATCCAAAGAGTGGGAA CAGGACCTGAAATCACTGAAAGAGAAAAATGAAAAACTATTTAAAAACTACCAAACATTGAAGACTTCC TTGGCATCTGGTGCCCAGGTTAATCCTACCACACAAGACAATAAGAATCCTCATGTTACATCAAGAGCT ACACAGTTAACCACAGAGAAAATTCGAGAGCTGGAAAATTCACTGCATGAAGCTAAAGAAAGTGCTATG CATAAGGAAAGCAAGATTATAAAGATGCAGAAAGAACTTGAGGTGACTAATGACATAATAGCAAAACTT CAAGCCAAAGTTCATGAATCAAATAAATGCCTTGAAAAAACAAAAGAGACAATTCAAGTACTTCAGGAC AAAGTTGCTTTAGGAGCTAAGCCATATAAAGAAGAAATTGAAGATCTCAAAATGAAGCTTGTGAAAATA GACCTAGAGAAAATGAAAAATGCCAAAGAATTTGAAAAGGAAATCAGTGCTACAAAAGCCACTGTAGAA TATCAAAAGGAAGTTATAAGGCTATTGAGAGAAAATCTCAGAAGAAGTCAACAGGCCCAAGATACCTCA GTGATATCAGAACATACTGATCCTCAGCCTTCAAATAAACCCTTAACTTGTGGAGGTGGCAGCGGCATT GTACAAAACACAAAAGCTCTTATTTTGAAAAGTGAACATATAAGGCTAGAAAAAGAAATTTCTAAGTTA AAGCAGCAAAATGAACAGCTAATAAAACAAAAGAATGAATTGTTAAGCAATAATCAGCATCTTTCCAAT GAGGTCAAAACTTGGAAGGAAAGAACCCTTAAAAGAGAGGCTCACAAACAAGTAACTTGTGAGAATTCT CCAAAGTCTCCTAAAGTGACTGGAACAGCTTCTAAAAAGAAACAAATTACACCCTCTCAATGCAAGGAA CGGAATTTACAAGATCCTGTGCCAAAGGAATCACCAAAATCTTGTTTTTTTGATAGCCGATCAAAGTCT TTACCATCACCTCATCCAGTTCGCTATTTTGATAACTCAAGTTTAGGCCTTTGTCCAGAGGTGCAAAAT GCAGGAGCAGAGAGTGTGGATTCTCAGCCAGGTCCTTGGCACGCCTCCTCAGGCAAGGATGTGCCTGAG TGCAAAACTCAG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG240253
Blue=ORF Red=Cloning site Green=Tag(s) MAEEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVYEEIAAP IIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVIPRAIHDIFQKIKKFPDREFLLRVSYMEIYNET ITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIF RMILESREKGEPSNCEGSVKVSHLNLVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQ VGGFINYRDSKLTRILQNSLGGNAKTRIICTITPVSFDETLTALQFASTAKYMKNTPYVNEVSTDEALL KRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELK AKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIE WNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQENEL SSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRS ENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCN LELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEV VHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKE AQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLE EVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEV SRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLE SVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKL KEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSI TKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIIN TQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEK FQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSE MEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLE TEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEV QEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKEN TKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEM RSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNE ISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQ EKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVM KERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDI QKDLDKSKDELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSL DLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESI NKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQ VLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWE QDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAM HKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKI DLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGI VQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKREAHKQVTCENS PKSPKVTGTASKKKQITPSQCKERNLQDPVPKESPKSCFFDSRSKSLPSPHPVRYFDNSSLGLCPEVQN AGAESVDSQPGPWHASSGKDVPECKTQ TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001286734 |
| ORF Size | 7740 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001286734.2 |
| RefSeq Size | 8267 bp |
| RefSeq ORF | 7743 bp |
| Locus ID | 1062 |
| UniProt ID | Q02224 |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| MW | 302.2 kDa |
| Gene Summary | Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014] |
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