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KIAA1199 (CEMIP) (NM_001293298) Human Tagged ORF Clone
CAT＃: RG240123
- TrueORF®
CEMIP (tGFP-tagged) - Human cell migration inducing protein, hyaluronan binding (CEMIP), transcript variant 1
ORF Plasmid: DDK
"NM_001293298" in other vectors (2)
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CNY 13,970.00
货期*
2周
规格
Product images
经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | CCSP1; HYBID; KIAA1199; TMEM2L |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG240123 representing NM_001293298.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGAGCTGCTGGGAGGCAGGACTTCCTCTTCAAGGCCATGCTGACCATCAGCTGGCTCACTCTGACC TGCTTCCCTGGGGCCACATCCACAGTGGCTGCTGGGTGCCCTGACCAGAGCCCTGAGTTGCAACCCTGG AACCCTGGCCATGACCAAGACCACCATGTGCATATCGGCCAGGGCAAGACACTGCTGCTCACCTCTTCT GCCACGGTCTATTCCATCCACATCTCAGAGGGAGGCAAGCTGGTCATTAAAGACCACGACGAGCCGATT GTTTTGCGAACCCGGCACATCCTGATTGACAACGGAGGAGAGCTGCATGCTGGGAGTGCCCTCTGCCCT TTCCAGGGCAATTTCACCATCATTTTGTATGGAAGGGCTGATGAAGGTATTCAGCCGGATCCTTACTAT GGTCTGAAGTACATTGGGGTTGGTAAAGGAGGCGCTCTTGAGTTGCATGGACAGAAAAAGCTCTCCTGG ACATTTCTGAACAAGACCCTTCACCCAGGTGGCATGGCAGAAGGAGGCTATTTTTTTGAAAGGAGCTGG GGCCACCGTGGAGTTATTGTTCATGTCATCGACCCCAAATCAGGCACAGTCATCCATTCTGACCGGTTT GACACCTATAGATCCAAGAAAGAGAGTGAACGTCTGGTCCAGTATTTGAACGCGGTGCCCGATGGCAGG ATCCTTTCTGTTGCAGTGAATGATGAAGGTTCTCGAAATCTGGATGACATGGCCAGGAAGGCGATGACC AAATTGGGAAGCAAACACTTCCTGCACCTTGGATTTAGACACCCTTGGAGTTTTCTAACTGTGAAAGGA AATCCATCATCTTCAGTGGAAGACCATATTGAATATCATGGACATCGAGGCTCTGCTGCTGCCCGGGTA TTCAAATTGTTCCAGACAGAGCATGGCGAATATTTCAATGTTTCTTTGTCCAGTGAGTGGGTTCAAGAC GTGGAGTGGACGGAGTGGTTCGATCATGATAAAGTATCTCAGACTAAAGGTGGGGAGAAAATTTCAGAC CTCTGGAAAGCTCACCCAGGAAAAATATGCAATCGTCCCATTGATATACAGGCCACTACAATGGATGGA GTTAACCTCAGCACCGAGGTTGTCTACAAAAAAGGCCAGGATTATAGGTTTGCTTGCTACGACCGGGGC AGAGCCTGCCGGAGCTACCGTGTACGGTTCCTCTGTGGGAAGCCTGTGAGGCCCAAACTCACAGTCACC ATTGACACCAATGTGAACAGCACCATTCTGAACTTGGAGGATAATGTACAGTCATGGAAACCTGGAGAT ACCCTGGTCATTGCCAGTACTGATTACTCCATGTACCAGGCAGAAGAGTTCCAGGTGCTTCCCTGCAGA TCCTGCGCCCCCAACCAGGTCAAAGTGGCAGGGAAACCAATGTACCTGCACATCGGGGAGGAGATAGAC GGCGTGGACATGCGGGCGGAGGTTGGGCTTCTGAGCCGGAACATCATAGTGATGGGGGAGATGGAGGAC AAATGCTACCCCTACAGAAACCACATCTGCAATTTCTTTGACTTCGATACCTTTGGGGGCCACATCAAG TTTGCTCTGGGATTTAAGGCAGCACACTTGGAGGGCACGGAGCTGAAGCATATGGGACAGCAGCTGGTG GGTCAGTACCCGATTCACTTCCACCTGGCCGGTGATGTAGACGAAAGGGGAGGTTATGACCCACCCACA TACATCAGGGACCTCTCCATCCATCATACATTCTCTCGCTGCGTCACAGTCCATGGCTCCAATGGCTTG TTGATCAAGGACGTTGTGGGCTATAACTCTTTGGGCCACTGCTTCTTCACGGAAGATGGGCCGGAGGAA CGCAACACTTTTGACCACTGTCTTGGCCTCCTTGTCAAGTCTGGAACCCTCCTCCCCTCGGACCGTGAC AGCAAGATGTGCAAGATGATCACAGAGGACTCCTACCCGGGGTACATCCCCAAGCCCAGGCAAGACTGC AATGCTGTGTCCACCTTCTGGATGGCCAATCCCAACAACAACCTCATCAACTGTGCCGCTGCAGGATCT GAGGAAACTGGATTTTGGTTTATTTTTCACCACGTACCAACGGGCCCCTCCGTGGGAATGTACTCCCCA GGTTATTCAGAGCACATTCCACTGGGAAAATTCTATAACAACCGAGCACATTCCAACTACCGGGCTGGC ATGATCATAGACAACGGAGTCAAAACCACCGAGGCCTCTGCCAAGGACAAGCGGCCGTTCCTCTCAATC ATCTCTGCCAGATACAGCCCTCACCAGGACGCCGACCCGCTGAAGCCCCGGGAGCCGGCCATCATCAGA CACTTCATTGCCTACAAGAACCAGGACCACGGGGCCTGGCTGCGCGGCGGGGATGTGTGGCTGGACAGC TGCCGGTTTGCTGACAATGGCATTGGCCTGACCCTGGCCAGTGGTGGAACCTTCCCGTATGACGACGGC TCCAAGCAAGAGATAAAGAACAGCTTGTTTGTTGGCGAGAGTGGCAACGTGGGGACGGAAATGATGGAC AATAGGATCTGGGGCCCTGGCGGCTTGGACCATAGCGGAAGGACCCTCCCTATAGGCCAGAATTTTCCA ATTAGAGGAATTCAGTTATATGATGGCCCCATCAACATCCAAAACTGCACTTTCCGAAAGTTTGTGGCC CTGGAGGGCCGGCACACCAGCGCCCTGGCCTTCCGCCTGAATAATGCCTGGCAGAGCTGCCCCCATAAC AACGTGACCGGCATTGCCTTTGAGGACGTTCCGATTACTTCCAGAGTGTTCTTCGGAGAGCCTGGGCCC TGGTTCAACCAGCTGGACATGGATGGGGATAAGACATCTGTGTTCCATGACGTCGACGGCTCCGTGTCC GAGTACCCTGGCTCCTACCTCACGAAGAATGACAACTGGCTGGTCCGGCACCCAGACTGCATCAATGTT CCCGACTGGAGAGGGGCCATTTGCAGTGGGTGCTATGCACAGATGTACATTCAAGCCTACAAGACCAGT AACCTGCGAATGAAGATCATCAAGAATGACTTCCCCAGCCACCCTCTTTACCTGGAGGGGGCGCTCACC AGGAGCACCCATTACCAGCAATACCAACCGGTTGTCACCCTGCAGAAGGGCTACACCATCCACTGGGAC CAGACGGCCCCCGCCGAACTCGCCATCTGGCTCATCAACTTCAACAAGGGCGACTGGATCCGAGTGGGG CTCTGCTACCCGCGAGGCACCACATTCTCCATCCTCTCGGATGTTCACAATCGCCTGCTGAAGCAAACG TCCAAGACGGGCGTCTTCGTGAGGACCTTGCAGATGGACAAAGTGGAGCAGAGCTACCCTGGCAGGAGC CACTACTACTGGGACGAGGACTCAGGGCTGTTGTTCCTGAAGCTGAAAGCTCAGAACGAGAGAGAGAAG TTTGCTTTCTGCTCCATGAAAGGCTGTGAGAGGATAAAGATTAAAGCTCTGATTCCAAAGAACGCAGGC GTCAGTGACTGCACAGCCACAGCTTACCCCAAGTTCACCGAGAGGGCTGTCGTAGACGTGCCGATGCCC AAGAAGCTCTTTGGTTCTCAGCTGAAAACAAAGGACCATTTCTTGGAGGTGAAGATGGAGAGTTCCAAG CAGCACTTCTTCCACCTCTGGAACGACTTCGCTTACATTGAAGTGGATGGGAAGAAGTACCCCAGTTCG GAGGATGGCATCCAGGTGGTGGTGATTGACGGGAACCAAGGGCGCGTGGTGAGCCACACGAGCTTCAGG AACTCCATTCTGCAAGGCATACCATGGCAGCTTTTCAACTATGTGGCGACCATCCCTGACAATTCCATA GTGCTTATGGCATCAAAGGGAAGATACGTCTCCAGAGGCCCATGGACCAGAGTGCTGGAAAAGCTTGGG GCAGACAGGGGTCTCAAGTTGAAAGAGCAAATGGCATTCGTTGGCTTCAAAGGCAGCTTCCGGCCCATC TGGGTGACACTGGACACTGAGGATCACAAAGCCAAAATCTTCCAAGTTGTGCCCATCCCTGTGGTGAAG AAGAAGAAGTTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG240123
Blue=ORF Red=Cloning site Green=Tag(s) MGAAGRQDFLFKAMLTISWLTLTCFPGATSTVAAGCPDQSPELQPWNPGHDQDHHVHIGQGKTLLLTSS ATVYSIHISEGGKLVIKDHDEPIVLRTRHILIDNGGELHAGSALCPFQGNFTIILYGRADEGIQPDPYY GLKYIGVGKGGALELHGQKKLSWTFLNKTLHPGGMAEGGYFFERSWGHRGVIVHVIDPKSGTVIHSDRF DTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDDMARKAMTKLGSKHFLHLGFRHPWSFLTVKG NPSSSVEDHIEYHGHRGSAAARVFKLFQTEHGEYFNVSLSSEWVQDVEWTEWFDHDKVSQTKGGEKISD LWKAHPGKICNRPIDIQATTMDGVNLSTEVVYKKGQDYRFACYDRGRACRSYRVRFLCGKPVRPKLTVT IDTNVNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCRSCAPNQVKVAGKPMYLHIGEEID GVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHICNFFDFDTFGGHIKFALGFKAAHLEGTELKHMGQQLV GQYPIHFHLAGDVDERGGYDPPTYIRDLSIHHTFSRCVTVHGSNGLLIKDVVGYNSLGHCFFTEDGPEE RNTFDHCLGLLVKSGTLLPSDRDSKMCKMITEDSYPGYIPKPRQDCNAVSTFWMANPNNNLINCAAAGS EETGFWFIFHHVPTGPSVGMYSPGYSEHIPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSI ISARYSPHQDADPLKPREPAIIRHFIAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDG SKQEIKNSLFVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQLYDGPINIQNCTFRKFVA LEGRHTSALAFRLNNAWQSCPHNNVTGIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSVFHDVDGSVS EYPGSYLTKNDNWLVRHPDCINVPDWRGAICSGCYAQMYIQAYKTSNLRMKIIKNDFPSHPLYLEGALT RSTHYQQYQPVVTLQKGYTIHWDQTAPAELAIWLINFNKGDWIRVGLCYPRGTTFSILSDVHNRLLKQT SKTGVFVRTLQMDKVEQSYPGRSHYYWDEDSGLLFLKLKAQNEREKFAFCSMKGCERIKIKALIPKNAG VSDCTATAYPKFTERAVVDVPMPKKLFGSQLKTKDHFLEVKMESSKQHFFHLWNDFAYIEVDGKKYPSS EDGIQVVVIDGNQGRVVSHTSFRNSILQGIPWQLFNYVATIPDNSIVLMASKGRYVSRGPWTRVLEKLG ADRGLKLKEQMAFVGFKGSFRPIWVTLDTEDHKAKIFQVVPIPVVKKKKL TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001293298 |
| ORF Size | 4083 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001293298.2 |
| RefSeq Size | 7287 bp |
| RefSeq ORF | 4086 bp |
| Locus ID | 57214 |
| UniProt ID | Q8WUJ3 |
| MW | 153.4 kDa |
| Gene Summary | Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.[UniProtKB/Swiss-Prot Function] |
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