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DIS (CCAR1) (NM_001282960) Human Tagged ORF Clone
CAT＃: RG240000
- TrueORF®
CCAR1 (tGFP-tagged) - Human cell division cycle and apoptosis regulator 1 (CCAR1), transcript variant 3
ORF Plasmid: DDK
"NM_001282960" in other vectors (2)
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CNY 11,690.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG240000 representing NM_001282960.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCTCAATTTGGAGGACAGAAGAATCCGCCATGGGCTACTCAGTTTACAGCCACTGCAGTATCACAG CCAGCTGCACTGGGTGTTCAACAGCCATCACTCCTTGGAGCATCTCCTACCATTTATACACAGCAAACT GCATTGGCAGCAGCAGGCCTTACCACACAAACTCCAGCAAACTATCAGTTAACACAAACTGCTGCATTG CAGCAACAAGCCGCAGCTGCAGCAGCTGCATTACAACAGTTACAGCAACCCCAGCAAACCCTCTTAACA CAGCCAGCTGTTGCACTGCCTACAAGCCTTAGCCTGTCTACTCCTCAGCCAACAGCACAAATAACTGTA TCATATCCAACACCAAGGTCCAGTCAACAGCAAACCCAGCCTCAGAAGCAGCGTGTTTTCACAGGGGTG GTTACAAAACTACATGATACGTTTGGATTTGTGGATGAAGATGTATTCTTTCAGCTTAGTGCTGTCAAA GGGAAAACCCCCCAAGTAGGTGACAGAGTATTGGTTGAAGCTACTTATAATCCTAATATGCCTTTTAAA TGGAATGCACAGAGAATTCAAACACTACCAAATCAGAATCAGTCGCAAACCCAGCCATTACTGAAGACT CCTCCTGCTGTACTTCAGCCAATTGCACCACAGACAACATTTGGTGTTCAGACTCAGCCCCAGCCCCAG TCACTGCTGCAGGCACAGATTTCAGCAGCTTCTATTACACCACTATTGCAGACTCAACCACAGCCCTTA TTACAGCAGCCTCAGCAAAAAGCTGGTTTATTGCAGCCTCCTGTTCGTATAGTTTCACAGCCACAACCG GCACGACGATTAGATCCCCCATCCCGATTTTCAGGAAGAAATGACAGAGGGGATCAAGTGCCTAACAGA AAAGATGATCGAAGTCGTGAGAGAGAGAGAGAAAGACGTAGATCGAGAGAAAGATCACCTCAGAGGAAA CGTTCCCGGGAAAGATCTCCACGAAGAGAGCGAGAGCGATCACCTCGGAGAGTTCGACGTGTTGTTCCA CGTTACACAGTTCAGTTTTCAAAGTTTTCTTTAGATTGTCCCAGTTGTGACATGATGGAACTAAGGCGC CGTTATCAAAATTTGTATATACCTAGTGACTTTTTTGATGCTCAATTTACATGGGTGGATGCTTTCCCT TTGTCAAGACCATTTCAGCTGGGAAATTACTGCAATTTTTATGTAATGCACAGAGAAGTAGAGTCCTTA GAAAAAAATATGGCCATTCTTGATCCACCAGATGCTGACCACTTATACAGTGCAAAGGTAATGCTGATG GCTAGCCCTAGTATGGAAGATTTATATCATAAGTCATGTGCTCTTGCTGAGGACCCACAAGAACTTCGA GATGGATTCCAACATCCTGCTAGACTTGTTAAGTTTTTAGTGGGCATGAAAGGCAAGGATGAAGCTATG GCCATTGGAGGCCACTGGTCTCCTTCGTTGGATGGACCAGACCCAGAAAAAGATCCCTCTGTGTTGATT AAGACTGCTATTCGTTGTTGTAAGGCTCTGACAGGCATTGATCTAAGTGTGTGCACACAATGGTACCGT TTTGCAGAGATTCGCTACCATCGCCCTGAGGAGACCCACAAGGGGCGTACAGTTCCAGCTCATGTGGAG ACAGTGGTTTTATTTTTCCCGGATGTTTGGCATTGCCTTCCCACCCGCTCAGAGTGGGAAACCCTCTCC CGAGGATACAAGCAGCAGCTGGTCGAGAAGCTTCAGGGTGAACGCAAGGAGGCTGATGGAGAACAGGAT GAAGAAGAGAAGGATGATGGTGAAGCTAAAGAAATTTCTACACCTACCCATTGGTCTAAACTTGATCCA AAGACAATGAAGGTAAATGACCTCCGAAAAGAATTAGAAAGTCGAGCTCTTAGTTCCAAAGGATTAAAA TCCCAGTTAATAGCCCGATTGACAAAACAGCTTAAAGTAGAGGAACAAAAAGAAGAACAGAAGGAGTTA GAGAAATCTGAAAAAGAAGAGGATGAGGATGATGATAGGAAATCTGAAGACGATAAAGAGGAAGAAGAA AGGAAACGTCAAGAGGAAATAGAACGCCAGCGTCGAGAAAGAAGATATATTTTGCCTGATGAACCGGCC ATCATTGTACATCCAAATTGGGCTGCAAAAAGTGGCAAGTTTGATTGTAGCATCATGTCTTTGAGTGTC CTATTGGACTACAGATTAGAGGATAATAAAGAACATTCATTTGAGGTTTCATTGTTTGCGGAACTTTTC AACGAAATGCTTCAAAGAGATTTTGGTGTCCGTATATACAAATCATTACTGTCTCTTCCTGAGAAAGAG GACAAAAAAGAAAAGGATAAAAAAAGCAAAAAAGATGAGAGAAAAGATAAAAAAGAAGAAAGAGATGAT GAAACTGATGAACCAAAACCCAAACGGAGAAAATCAGGCGATGATAAAGATAAAAAAGAAGATAGAGAT GAAAGGAAGAAAGAAGATAAAAGAAAAGATGATTCTAAAGATGATGATGAAACTGAAGAAGATAACAAT CAAGATGAATATGACCCTATGGAAGCAGAAGAAGCTGAGGATGAAGAAGATGATAGGGATGAGGAAGAA ATGACCAAACGAGATGACAAAAGAGATATCAACAGATACTGCAAGGAGAGGCCCTCTAAAGATAAGGAA AAAGAAAAGACTCAAATGATCACAATTAACAGAGATCTGTTAATGGCTTTTGTTTATTTTGATCAAAGT CATTGTGGTTACCTTCTTGAAAAGGATTTGGAAGAAATACTTTATACTCTTGGACTACATCTTTCTCGG GCTCAGGTAAAGAAGCTTCTTAATAAAGTAGTGCTCCGTGAATCTTGCTTTTACCGGAAATTAACAGAC ACCTCAAAAGATGAAGAGAACCATGAAGAGTCTGAGTCATTGCAGGAAGATATGCTAGGAAACAGATTA TTACTTCCAACACCAACAGTAAAGCAGGAATCAAAGGATGTGGAAGAAAATGTTGGCCTCATTGTGTAC AATGGTGCAATGGTAGATGTAGGAAGCCTCTTGCAAAAATTGGAAAAGAGCGAAAAAGTAAGAGCTGAG GTAGAACAGAAGCTGCAGTTACTAGAAGAAAAAACAGATGAAGATGAAAAAACCATATTAAATTTGGAG AATTCCAACAAAAGCCTCTCTGGTGAACTCAGAGAAGTTAAAAAGGACCTTAGTCAGTTACAAGAAAAC TTAAAGATTTCGGAAAACATGAATTTACAATTTGAAAACCAAATGAATAAGACAATCAGAAACTTATCT ACGGTAATGGATGAAATCCACACTGTTCTCAAGAAGGATAATGTAAAGAATGAAGACAAAGATCAAAAA TCCAAGGAGAATGGTGCCAGTGTA ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG240000
Blue=ORF Red=Cloning site Green=Tag(s) MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAAL QQQAAAAAAALQQLQQPQQTLLTQPAVALPTSLSLSTPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGV VTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKT PPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQP ARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVP RYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESL EKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAM AIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVE TVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDP KTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEE RKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELF NEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRD ERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKE KEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTD TSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAE VEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLS TVMDEIHTVLKKDNVKNEDKDQKSKENGASV TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001282960 |
| ORF Size | 3405 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001282960.2 |
| RefSeq Size | 4724 bp |
| RefSeq ORF | 3408 bp |
| Locus ID | 55749 |
| UniProt ID | Q8IX12 |
| MW | 131.5 kDa |
| Gene Summary | Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation (PubMed:12816952). In association with CALCOCO1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). Can act as a both a coactivator and corepressor of AR-mediated transcription. Contributes to chromatin looping and AR transcription complex assembly by stabilizing AR-GATA2 association on chromatin and facilitating MED1 and RNA polymerase II recruitment to AR-binding sites. May play an important role in the growth and tumorigenesis of prostate cancer cells (PubMed:23887938).[UniProtKB/Swiss-Prot Function] |
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