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PHF17 (JADE1) (NM_001287439) Human Tagged ORF Clone
CAT＃: RG239666
- TrueORF®
JADE1 (tGFP-tagged) - Human jade family PHD finger 1 (JADE1), transcript variant 4
ORF Plasmid: DDK
"NM_001287439" in other vectors (2)
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CNY 7,510.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | PHF17 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG239666 representing NM_001287439.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAAACGAGGTCGCCTTCCCAGCAGCAGTGAGGATTCTGACGACAATGGCAGCCTGTCAACTACTTGG TCCCAGAATTCCCGATCCCAGCATAGGAGAAGCTCCTGCTCCAGACATGAAGATCGAAAGCCTTCAGAG GTGTTTAGGACAGACCTGATCACTGCCATGAAGTTGCATGACTCCTACCAGCTGAATCCGGATGAGTAC TATGTGTTGGCAGATCCCTGGAGACAGGAATGGGAGAAAGGGGTCCAGGTGCCTGTGAGCCCGGGGACC ATCCCTCAGCCTGTGGCCAGGGTTGTGTCTGAAGAGAAATCCCTCATGTTCATCAGGCCCAAGAAGTAC ATCGTGTCATCAGGCTCTGAGCCTCCCGAGTTGGGCTATGTGGACATCCGGACGCTGGCTGACAGCGTG TGTCGCTATGACCTCAATGACATGGATGCTGCATGGCTGGAACTGACCAATGAAGAATTTAAGGAGATG GGAATGCCTGAACTAGATGAATACACCATGGAGAGGGTCCTAGAGGAATTTGAGCAGCGATGCTACGAC AATATGAATCATGCCATAGAGACTGAGGAAGGCCTGGGGATCGAATATGATGAAGATGTTGTCTGTGAT GTCTGCCAGTCTCCTGATGGTGAGGACGGCAATGAGATGGTGTTCTGTGACAAATGCAACATCTGTGTG CACCAGGCCTGTTATGGAATCCTCAAGGTACCAGAGGGCAGCTGGCTGTGCCGGACATGTGCCCTGGGG GTTCAGCCAAAATGTCTGCTGTGTCCGAAGAAGGGTGGAGCTATGAAGCCCACCCGTAGCGGAACCAAG TGGGTCCACGTTAGCTGTGCTCTGTGGATCCCTGAGGTGAGCATTGGCAGCCCAGAGAAGATGGAGCCC ATCACCAAGGTGTCACACATTCCCAGCAGCCGGTGGGCGCTAGTGTGCAGCCTCTGCAATGAGAAGTTT GGGGCCTCTATACAGTGCTCTGTGAAGAACTGCCGCACAGCCTTCCATGTGACCTGTGCTTTTGACCGG GGCCTGGAGATGAAGACCATCTTAGCAGAGAATGATGAAGTCAAGTTCAAGTCCTATTGCCCAAAGCAC AGCTCACATAGGAAACCCGAGGAGAGTCTTGGCAAGGGGGCTGCACAGGAGAATGGGGCCCCTGAGTGT TCCCCCCGGAATCCGCTGGAGCCCTTTGCCAGCCTTGAGCAGAACCGGGAGGAGGCCCACCGGGTGAGT GTCCGTAAGCAGAAGCTGCAGCAGTTGGAGGATGAGTTCTACACCTTCGTCAACCTGCTGGATGTTGCC AGGGCTCTGCGGCTGCCTGAGGAAGTAGTGGATTTCCTGTACCAGTACTGGAAGTTGAAGAGGAAGGTC AACTTCAACAAGCCCCTGATCACCCCAAAGAAAGATGAAGAGGACAATCTAGCCAAGCGGGAGCAGGAT GTCTTATTTAGGAGGCTGCAGCTGTTCACGCACCTGCGGCAGGACCTGGAGAGGGTTCGGAACCTCACT TACATGGTGACCCGCAGGGAAAAGATTAAACGGTCTGTGTGCAAAGTCCAGGAACAGATATTCAATCTT TACACTAAGCTTTTGGAGCAAGAAAGAGTTTCAGGTGTGCCTTCTTCCTGCTCCTCCTCCTCACTGGAA AACATGCTTTTGTTTAACAGTCCTTCTGTTGGCCCTGATGCTCCCAAGATAGAGGACTTGAAGTGGCAT TCTGCATTCTTCAGAAAACAAATGGGTACTTCCTTGGTTCATTCGCTGAAAAAGCCCCATAAGCGAGAT CCTTTGCAGAATAGCCCTGGAAGTGAAGGCAAAACCCTGCTGAAGCAGCCAGACCTGTGTGGTAGAAGG GAGGGGATGGTGGTCCCAGAGAGCTTTTTGGGTTTAGAAAAGACCTTTGCAGAAGCACGTCTCATATCA GCACAACAGAAAAATGGTGTGGTGATGCCAGACCATGGGAAAAGAAGAGACAATCGTTTTCATTGTGAT CTCATTAAAGGAGACTTAAAGGACAAATCTTTTAAACAGAGTCACAAGCCTCTCAGGTCCACAGATGTG TCCCAGAGGCATCTGGACAACACAAGAGCTGCCACCTCCCCTGGAGTGGGGCAGTCAGCACCTGGCACA AGGAAGGAGATAGTGCCCAAGTGCAATGGCTCCCTAATCAAAGTAAACTATAATCAGACTGCAGTCAAA GTGCCTACAACACCTGCCAGCCCAGTGAAAAACTGGGGAGGATTCCGGATTCCAAAGAAGGGGGAACGG CAGCAGCAGGGAGAGGCCCACGATGGGGCCTGCCACCAGCACTCAGACTACCCATATTTGGGCTTAGGC CGAGTTCCAGCCAAGGAAAGGGCAAAAAGCAAATTAAAATCCGACAATGAGAATGACGGGTATGTCCCC GATGTGGAAATGAGTGACTCAGAGAGTGAGGCATCAGAAAAGAAATGTATACACACCAGCAGCACTATC AGCAGAAGGACAGACATTATCAGGAGAAGCATCTTGGCTTCT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239666
Blue=ORF Red=Cloning site Green=Tag(s) MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHDSYQLNPDEY YVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSV CRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCD VCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTK WVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDR GLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVS VRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQD VLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVSGVPSSCSSSSLE NMLLFNSPSVGPDAPKIEDLKWHSAFFRKQMGTSLVHSLKKPHKRDPLQNSPGSEGKTLLKQPDLCGRR EGMVVPESFLGLEKTFAEARLISAQQKNGVVMPDHGKRRDNRFHCDLIKGDLKDKSFKQSHKPLRSTDV SQRHLDNTRAATSPGVGQSAPGTRKEIVPKCNGSLIKVNYNQTAVKVPTTPASPVKNWGGFRIPKKGER QQQGEAHDGACHQHSDYPYLGLGRVPAKERAKSKLKSDNENDGYVPDVEMSDSESEASEKKCIHTSSTI SRRTDIIRRSILAS TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001287439 |
| ORF Size | 2526 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001287439.2 |
| RefSeq Size | 5890 bp |
| RefSeq ORF | 2529 bp |
| Locus ID | 79960 |
| UniProt ID | Q6IE81 |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 96 kDa |
| Gene Summary | Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function.[UniProtKB/Swiss-Prot Function] |
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