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DOK5 (NM_177959) Human Tagged ORF Clone
CAT＃: RG236491
- TrueORF®
DOK5 (tGFP-tagged) - Human docking protein 5 (DOK5), transcript variant 2
ORF Plasmid: DDK
"NM_177959" in other vectors (2)
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CNY 4,370.00
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | C20orf180; IRS-6; IRS6 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG236491 representing NM_177959.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAGTGTGTAGGAACACGGATCAATGACATCAGCCTTGGAGAGCCTGACTTACTGGCCACTGGGGTT GAGAGAGAACAGAGTGAGAGATTCAATGTGTATTTGATGCCATCTCCTAACTTAGATGTACATGGCGAA TGTGCCTTGCAGATTACATATGAGTATATCTGTCTTTGGGACGTCCAGAATCCCAGAGTCAAACTCATC TCTTGGCCGCTAAGCGCCCTGCGGCGGTATGGACGTGATACTACGTGGTTCACTTTTGAGGCAGGGAGG ATGTGTGAGACTGGTGAAGGGCTGTTTATCTTTCAGACCCGAGACGGGGAGGCCATCTATCAGAAAGTC CACTCTGCTGCCTTGGCCATAGCCGAGCAGCACGAGCGCTTGCTACAGAGTGTGAAAAACTCGATGCTC CAGATGAAGATGAGTGAGCGGGCCGCCTCGCTGAGCACCATGGTGCCCCTGCCTCGCAGCGCCTACTGG CAGCACATCACACGGCAGCACAGCACGGGACAGCTCTACCGCTTGCAAGATGTTTCCAGCCCTCTGAAG CTTCATCGAACAGAGACTTTTCCAGCCTACAGATCTGAGCAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG236491
Blue=ORF Red=Cloning site Green=Tag(s) MECVGTRINDISLGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLI SWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSML QMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFPAYRSEH TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_177959 |
| ORF Size | 594 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_177959.3 |
| RefSeq Size | 1734 bp |
| RefSeq ORF | 597 bp |
| Locus ID | 55816 |
| UniProt ID | Q9P104 |
| Protein Families | Druggable Genome |
| MW | 23.3 kDa |
| Gene Summary | The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
Documents
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