MGP (NM_001190839) Human Tagged ORF Clone
CAT#: RG230966
- TrueORF®
MGP (tGFP-tagged) - Human matrix Gla protein (MGP), transcript variant 1
ORF Plasmid: DDK
"NM_001190839" in other vectors (3)
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CNY 2,920.00
CNY 4,370.00
Cited in 1 publication. |
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | GIG36; MGLAP; NTI |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001190839 |
ORF Size | 384 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001190839.3 |
RefSeq Size | 1473 bp |
RefSeq ORF | 387 bp |
Locus ID | 4256 |
UniProt ID | P08493 |
Protein Families | Secreted Protein |
Gene Summary | This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia. [provided by RefSeq, Sep 2016] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation
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JCI Insight
,PubMed ID 28422762
[MGP]
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Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC230966 | MGP (Myc-DDK-tagged)-Human matrix Gla protein (MGP), transcript variant 1 |
CNY 3,990.00 |
|
RC230966L3 | Lenti-ORF clone of MGP (Myc-DDK-tagged)-Human matrix Gla protein (MGP), transcript variant 1 |
CNY 5,890.00 |
|
RC230966L4 | Lenti-ORF clone of MGP (mGFP-tagged)-Human matrix Gla protein (MGP), transcript variant 1 |
CNY 5,890.00 |