United States
Germany
Japan
United Kingdom
China
SENP6 (NM_001100409) Human Tagged ORF Clone
CAT＃: RG217424
- TrueORF®
SENP6 (tGFP-tagged) - Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2
ORF Plasmid: DDK
"NM_001100409" in other vectors (4)
Need custom modification / cloning service?
Get a free quote
CNY 10,064.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | SSP1; SUSP1 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG217424 representing NM_001100409
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCCGGCAAGAGCGGCGGTAGCGCAGGGGAGATTACTTTTCTGGAAGCTTTGGCTAGATCAGAGT CTAAGAGAGATGGAGGTTTTAAAAATAATTGGAGCTTTGATCATGAAGAAGAAAGTGAAGGAGATACAGA TAAAGATGGGACAAATCTGCTCAGTGTGGATGAAGATGAGGATTCTGAAACCTCAAAAGGAAAAAAGTTA AATCGTCGATCTGAAATTGTTGCTAATAGCTCTGGTGAATTCATCTTGAAGACATATGTAAGACGAAACA AGTCTGAAAGTTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAGAAATT GAGTGAAAATACGCAAAATACGTCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCATCATGCT CATGCACAGATACCAGTAGTAAAAACAGCAGCCCAAAGGAAAGAATACCCACCTCATGTCCAAAAAGTTG AAATTAATCCTGTAAGGTTAAGTCGGCTCCAAGGTGTTGAACGTATAATGAAGAAAACAGAAGAGTCCGA ATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAGAAACGACACTGTAGTACCTATCAGCCTACT CCTCCTCTATCTCCTGCTTCAAAAAAATGTTTAACCCATTTAGAGGATTTGCAAAGAAATTGCAGACAAG CTATTACTTTGAATGAGTCTACTGGACCATTATTAAGAACGTCAATTCATCAGAATTCTGGAGGACAGAA GTCACAAAACACAGGATTAACAACCAAGAAGTTTTATGGCAACAATGTGGAAAAGGTTCCAATTGATATT ATTGTGAATTGTGATGACAGTAAACACACTTATTTACAGACTAATGGAAAAGTCATTTTACCTGGGGCAA AAATACCCAAAATCACAAACTTGAAAGAAAGGAAAACAAGTTTGTCAGACCTAAATGATCCAATCATTTT GTCCAGTGATGATGATGATGACAACGACAGAACTAACAGAAGAGAAAGCATATCTCCTCAGCCTGCTGAT TCAGCATGTTCTTCCCCTGCACCATCCACTGGAAAAGTAGAAGCAGCGCTAAATGAAAATACTTGCAGAG CAGAGCGTGAACTACGAAGCATTCCAGAAGACTCAGAGTTAAATACAGTTACATTGCCAAGAAAAGCAAG AATGAAAGACCAGTTTGGCAATTCTATTATCAACACACCTCTGAAACGTCGTAAAGTGTTTTCTCAAGAA CCTCCAGATGCTTTAGCTTTAAGCTGCCAAAGTTCCTTTGACAGTGTCATTTTAAACTGTCGAAGTATAC GAGTAGGAACACTCTTCCGGCTGTTAATAGAGCCTGTAATTTTTTGTTTAGATTTTATCAAGATACAGCT AGACGAACCAGACCATGATCCTGTAGAGATTATATTAAATACCTCTGATCTAACTAAATGTGAATGGTGT AATGTCCGAAAATTACCTGTAGTGTTTCTTCAAGCAATTCCAGCAGTTTATCAAAAGCTGAGCATCCAAC TGCAAATGAATAAGGAGGATAAAGTTTGGAATGATTGTAAAGGAGTAAATAAATTAACAAATTTAGAAGA ACAATATATAATTTTAATTTTTCAAAATGGCCTTGATCCTCCGGCAAATATGGTATTTGAAAGTATCATT AATGAAATTGGTATAAAGAATAACATCTCCAATTTTTTTGCGAAAATTCCCTTTGAAGAAGCTAATGGCA GACTTGTTGCCTGTACAAGAACCTATGAAGAGAGCATCAAAGGAAGTTGTGGGCAAAAGGAAAACAAAAT TAAAACTGTATCATTTGAATCTAAAATACAACTTAGAAGCAAACAAGAATTTCAGTTTTTTGATGAAGAA GAAGAAACTGGAGAAAACCACACCATCTTCATTGGCCCAGTAGAAAAGTTGATAGTATATCCACCACCTC CAGCTAAGGGAGGCATCTCTGTTACCAATGAGGACCTGCACTGTCTAAATGAAGGAGAATTTTTAAATGA TGTTATTATAGACTTTTATTTGAAATACTTGGTGCTTGAAAAACTGAAGAAGGAAGACGCTGACCGAATT CATATATTCAGTTCTTTTTTCTATAAACGCCTTAATCAGAGAGAGAGGAGAAATCATGAAACAACTAATC TGTCAATACAGCAAAAACGGCATGGGAGAGTAAAAACATGGACCCGGCACGTAGATATTTTTGAGAAGGA TTTTATTTTTGTACCCCTTAATGAAGCTGCACACTGGTTTTTGGCTGTTGTTTGTTTCCCCGGTTTGGAA AAACCAAAGTATGAACCTAATCCTCATTACCATGAAAATGCTGTCATACAGAAATGTTCAACTGTAGAGG ACAGTTGTATTTCTTCTTCAGCCAGTGAAATGGAGAGTTGTTCACAAAACTCTTCTGCCAAGCCTGTAAT TAAGAAGATGCTAAACAAAAAACATTGCATAGCTGTAATTGATTCCAATCCTGGGCAGGAAGAAAGTGAC CCTCGTTATAAGAGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAATAAATCATACTGCGAGTGAAA ATGAAGAATTCAATAAAGGAGAATCTACATCCCAGAAAGTTGCTGATAGGACTAAAAGTGAGAATGGCCT ACAGAATGAAAGTTTAAGTTCCACACATCATACAGATGGCTTAAGCAAAATCAGACTAAACTATAGCGAT GAATCACCTGAAGCTGGTAAAATGCTTGAAGATGAACTCGTCGACTTCTCAGAAGATCAGGATAACCAGG ATGATAGCAGTGACGATGGATTCCTCGCTGATGACAACTGCAGTTCAGAAATAGGACAGTGGCATTTAAA GCCTACTATCTGTAAACAACCTTGTATCCTACTTATGGACTCACTCCGAGGCCCTTCTCGGTCAAATGTT GTCAAAATTTTAAGAGAGTATTTAGAAGTGGAATGGGAAGTTAAAAAAGGAAGCAAAAGAAGTTTTTCCA AAGATGTTATGAAGGGCTCTAATCCAAAAGTACCACAGCAAAACAACTTCAGTGACTGTGGTGTATATGT ATTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTCAGTTTTGAACTACCTATGAATTTGGCAAAC TGGTTTCCTCCACCAAGAATGAGAACAAAAAGAGAAGAAATCCGAAACATAATTCTGAAGCTACAGGAAG ATCAGAGCAAAGAGAAAAGAAAGCATAAGGACACTTACTCAACAGAAGCACCTTTAGGCGAAGGAACAGA ACAATATGTCAATAGTATCTCAGAT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG217424 representing NM_001100409
Red=Cloning site Green=Tags(s) MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKL NRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHA HAQIPVVKTAAQRKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPT PPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDI IVNCDDSKHTYLQTNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPAD SACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKRRKVFSQE PPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSDLTKCEWC NVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESII NEIGIKNNISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEE EETGENHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRI HIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLE KPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESD PRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSD ESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNV VKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLAN WFPPPRMRTKREEIRNIILKLQEDQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001100409 |
| ORF Size | 3315 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001100409.3 |
| RefSeq Size | 6624 bp |
| RefSeq ORF | 3318 bp |
| Locus ID | 26054 |
| UniProt ID | Q9GZR1 |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217424 | SENP6 (Myc-DDK-tagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2 |
CNY 11,020.00 |
|
| RC217424L3 | Lenti-ORF clone of SENP6 (Myc-DDK-tagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2 |
CNY 12,920.00 |
|
| RC217424L4 | Lenti-ORF clone of SENP6 (mGFP-tagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2 |
CNY 12,920.00 |
|
| SC316860 | SENP6 (untagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2 |
CNY 10,450.00 |
