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Noradrenaline transporter (SLC6A2) (NM_001172504) Human Tagged ORF Clone
CAT＃: RC230368
- TrueORF®
SLC6A2 (Myc-DDK-tagged)-Human solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 (SLC6A2), transcript variant 1. Note: ORF is codon optimized
ORF Plasmid: tGFP
"NM_001172504" in other vectors (4)
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CNY 4,680.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | NAT1; NET; NET1; SLC6A5 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC230368 ORF sequence, codon optimized.
Due to the complexity of NM_001172504, the ORF clone is codon optimized for mammalian Expression. The nucleotide sequence differs from the reference sequence, yet the amino acid sequence remains identical. Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTGCTCGCGCGAATGAATCCACAAGTGCAGCCTGAGAACAATGGCGCTGATACAGGCCCCGAGCAGC CCCTGAGGGCACGGAAAACCGCGGAACTCCTGGTTGTTAAGGAACGCAATGGTGTTCAATGTCTTCTGGC ACCACGCGATGGCGATGCCCAGCCCAGAGAGACGTGGGGCAAGAAAATCGATTTTTTGCTTTCAGTGGTG GGGTTTGCCGTGGATCTGGCAAATGTGTGGCGATTTCCATACCTGTGTTACAAAAATGGCGGAGGGGCTT TCTTGATCCCCTACACCCTCTTTCTGATAATCGCTGGGATGCCGCTGTTCTATATGGAGCTCGCCCTGGG CCAGTACAATCGCGAAGGTGCCGCCACAGTCTGGAAAATATGCCCGTTTTTCAAAGGCGTTGGCTATGCT GTCATCCTGATCGCCCTGTACGTTGGCTTCTACTACAACGTCATCATCGCCTGGTCACTCTACTACCTCT TCTCCTCCTTCACCCTCAACCTGCCCTGGACCGACTGTGGCCACACCTGGAACAGCCCCAACTGTACCGA CCCCAAGCTCCTCAATGGCTCCGTGCTTGGCAACCACACCAAGTACTCCAAGTACAAGTTCACGCCGGCA GCCGAGTTTTATGAGCGTGGTGTCCTGCACCTTCACGAGAGCAGCGGGATTCATGACATCGGCCTGCCCC AGTGGCAGCTCTTGCTCTGTCTGATGGTCGTCGTCATCGTCTTGTATTTTAGCCTCTGGAAAGGGGTGAA GACATCAGGAAAGGTGGTGTGGATCACAGCCACGCTGCCTTACTTCGTGCTGTTCGTGCTCCTGGTCCAT GGCGTCACGCTGCCCGGAGCCTCCAATGGCATCAATGCCTACCTGCACATCGACTTCTACCGCTTGAAAG AGGCCACGGTATGGATTGATGCCGCAACTCAGATATTTTTTTCCTTGGGGGCTGGATTTGGAGTATTGAT TGCATTTGCCAGTTACAACAAATTTGACAACAACTGTTACAGGGATGCCCTGCTGACCAGCAGCATCAAC TGTATCACCAGCTTCGTCTCTGGGTTCGCCATCTTCTCCATCCTTGGTTACATGGCCCATGAACACAAGG TCAACATTGAGGATGTGGCCACAGAAGGAGCTGGCCTAGTGTTCATCCTGTATCCAGAGGCCATTTCTAC CCTGTCTGGATCTACATTCTGGGCTGTTGTGTTTTTCGTCATGCTCCTGGCGCTGGGCCTTGACAGCTCA ATGGGAGGCATGGAGGCTGTCATCACGGGCCTGGCAGATGACTTCCAGGTCCTGAAGCGACACCGGAAAC TCTTCACATTTGGCGTCACCTTCAGCACTTTCCTTCTCGCCCTGTTCTGCATAACCAAGGGTGGAATTTA CGTCTTGACCCTCCTGGACACCTTTGCTGCGGGCACCTCCATCCTTTTTGCTGTCCTCATGGAAGCCATC GGAGTTTCCTGGTTTTATGGAGTGGACAGGTTCAGCAACGACATCCAGCAGATGATGGGGTTCAGGCCGG GTCTATACTGGAGACTGTGCTGGAAGTTCGTCAGTCCTGCCTTCCTCCTGTTCGTGGTTGTGGTCAGCAT CATCAACTTCAAGCCACTCACCTACGACGACTACATCTTCCCGCCCTGGGCCAACTGGGTGGGGTGGGGC ATCGCCCTGTCCTCCATGGTCCTGGTGCCCATCTACGTCATCTATAAGTTCCTCAGCACGCAGGGCTCTC TTTGGGAGAGACTGGCCTATGGCATCACGCCAGAGAACGAGCACCACCTGGTGGCTCAGAGGGACATCAG ACAGTTCCAGATGAAAACGAGACAAGGGAGAAGGAGAGCTACCAACTCTTGCCAGATATCCTGC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC230368 representing NM_001172504
Red=Cloning site Green=Tags(s) MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVV GFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYA VILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPA AEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVH GVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSIN CITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSS MGGMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAI GVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIFPPWANWVGWG IALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHLVAQRDIRQFQMKTRQGRRRATNSCQISC TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001172504 |
| ORF Size | 1884 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001172504.1, NP_001165975.1 |
| RefSeq Size | 2858 bp |
| RefSeq ORF | 1887 bp |
| Locus ID | 6530 |
| UniProt ID | P23975 |
| Protein Families | Druggable Genome, Transmembrane |
| MW | 70.5 kDa |
| Gene Summary | This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC230368L3 | Lenti-ORF clone of SLC6A2 (Myc-DDK-tagged)-Human solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 (SLC6A2), transcript variant 1. Note: ORF is codon optimized |
CNY 6,460.00 |
|
| RC230368L4 | Lenti-ORF clone of SLC6A2 (mGFP-tagged)-Human solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 (SLC6A2), transcript variant 1. Note: ORF is codon optimized |
CNY 6,460.00 |
|
| RG230368 | SLC6A2 (tGFP-tagged) - Human solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 (SLC6A2), transcript variant 1. Note: ORF is codon optimized |
CNY 6,280.00 |
|
| SC329006 | SLC6A2 (untagged)-Human solute carrier family 6 (neurotransmitter transporter noradrenalin) member 2 (SLC6A2) transcript variant 1 |
CNY 4,680.00 |
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