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NRG3 (NM_001165972) Human Tagged Lenti ORF Clone
CAT＃: RC228998L4
- LentiORF®
Lenti-ORF clone of NRG3 (mGFP-tagged)-Human neuregulin 3 (NRG3), transcript variant 2
"NM_001165972" in other vectors (4)
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CNY 5,890.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | mGFP |
| Synonyms | HRG3; pro-NRG3 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC228998).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001165972 |
| ORF Size | 2085 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001165972.1, NP_001159444.1 |
| RefSeq ORF | 2088 bp |
| Locus ID | 10718 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ErbB signaling pathway |
| MW | 74.7 kDa |
| Gene Summary | This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228998 | NRG3 (Myc-DDK-tagged)-Human neuregulin 3 (NRG3), transcript variant 2 |
CNY 3,990.00 |
|
| RC228998L3 | Lenti-ORF clone of NRG3 (Myc-DDK-tagged)-Human neuregulin 3 (NRG3), transcript variant 2 |
CNY 5,890.00 |
|
| RG228998 | NRG3 (tGFP-tagged) - Human neuregulin 3 (NRG3), transcript variant 2 |
CNY 4,370.00 |
|
| SC327633 | NRG3 (untagged)-Human neuregulin 3 (NRG3) transcript variant 2 |
CNY 7,220.00 |
