Uromucoid (UMOD) (NM_003361) Human Tagged Lenti ORF Clone
CAT#: RC223787L4
- LentiORF®
Lenti ORF clone of Human uromodulin (UMOD), transcript variant 1, mGFP tagged
"NM_003361" in other vectors (4)
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CNY 5,890.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Synonyms | ADMCKD2; ADTKD1; FJHN; HNFJ; HNFJ1; MCKD2; THGP; THP |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC223787).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_003361 |
ORF Size | 1920 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_003361.2 |
RefSeq Size | 2327 bp |
RefSeq ORF | 1923 bp |
Locus ID | 7369 |
UniProt ID | P07911 |
Domains | zona_pellucida, EGF_CA, EGF, EGF |
MW | 69.76 kDa |
Gene Summary | The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC223787 | UMOD (Myc-DDK-tagged)-Human uromodulin (UMOD), transcript variant 1 |
CNY 4,768.00 |
|
RC223787L3 | Lenti ORF clone of Human uromodulin (UMOD), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RG223787 | UMOD (tGFP-tagged) - Human uromodulin (UMOD), transcript variant 1 |
CNY 6,368.00 |
|
SC314301 | UMOD (untagged)-Human uromodulin (UMOD), transcript variant 1 |
CNY 4,776.00 |
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