ATRX (NM_138270) Human Tagged ORF Clone
CAT#: RC219519
- TrueORF®
ATRX (Myc-DDK-tagged)-Human alpha thalassemia/mental retardation syndrome X-linked (ATRX), transcript variant 2
ORF Plasmid: tGFP
"NM_138270" in other vectors (2)
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CNY 16,200.00
CNY 300.00
CNY 1,999.00
CNY 3,600.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | JMS; MRX52; RAD54; RAD54L; XH2; XNP; ZNF-HX |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC219519 representing NM_138270
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACCGCTGAGCCCATGAGTGAAAGCAAGTTGAATACATTGGTGCAGAAGCTTCATGACTTCCTTGCAC ACTCATCAGAAGAATCTGAAGAAACAAGTTCTCCTCCACGACTTGCAATGAATCAAAACACAGATAAAAT CAGTGGTTCTGGAAGTAACTCTGATATGATGGAAAACAGCAAGGAAGAGGGAACTAGCTCTTCAGAAAAA TCCAAGTCTTCAGGATCGTCACGATCAAAGAGGAAACCTTCAATTGTAACAAAGTATGTAGAATCAGATG ATGAAAAACCTTTGGATGATGAAACTGTAAATGAAGATGCGTCTAATGAAAATTCAGAAAATGATATTAC TATGCAGAGCTTGCCAAAAGAAGATGGGCTTCATGGGATTGTGAGCTGCACTGCTTGTGGACAACAGGTC AATCATTTTCAAAAAGATTCCATTTATAGACACCCTTCATTGCAAGTTCTTATTTGTAAGAATTGCTTTA AGTATTACATGAGTGATGATATTAGCCGTGACTCAGATGGAATGGATGAACAATGTAGGTGGTGTGCGGA AGGTGGAAACTTGATTTGTTGTGACTTTTGCCATAATGCTTTCTGCAAGAAATGCATTCTACGCAACCTT GGTCGAAAGGAGTTGTCCACAATAATGGATGAAAACAACCAATGGTATTGCTACATTTGTCACCCAGAGC CTTTGTTGGACTTGGTCACTGCATGTAACAGCGTATTTGAGAATTTAGAACAGTTGTTGCAGCAAAATAA GAAGAAGATAAAAGTTGACAGTGAAAAGAGTAATAAAGTATATGAACATACATCCAGATTTTCTCCAAAG AAGACTAGTTCAAATTGTAATGGAGAAGAAAAGAAATTAGATGATTCCTGTTCTGGCTCTGTAACCTACT CTTATTCCGCACTAATTGTGCCCAAAGAGATGATTAAGAAGGCAAAAAAACTGATTGAGACCACAGCCAA CATGAACTCCAGTTATGTTAAATTTTTAAAGCAGGCAACAGATAATTCAGAAATCAGTTCTGCTACAAAA TTACGTCAGCTTAAGGCTTTTAAGTCTGTGTTGGCTGATATTAAGAAGGCTCATCTTGCATTGGAAGAAG ACTTAAATTCCGAGTTTCGAGCGATGGATGCTGTAAACAAAGAGAAAAATACCAAAGAGCATAAAGTCAT AGATGCTAAGTTTGAAACAAAAGCACGAAAAGGAGAAAAACCTTGTGCTTTGGAAAAGAAGGATATTTCA AAGTCAGAAGCTAAACTTTCAAGAAAACAGGTAGATAGTGAGCACATGCATCAGAATGTTCCAACAGAGG AACAAAGAACAAATAAAAGTACCGGTGGTGAACATAAGAAATCTGATAGAAAAGAAGAACCTCAATATGA ACCTGCCAACACTTCTGAAGATTTAGACATGGATATTGTGTCTGTTCCTTCCTCAGTTCCAGAAGACATT TTTGAGAATCTTGAGACTGCTATGGAAGTTCAGAGTTCAGTTGATCATCAAGGGGATGGCAGCAGTGGAA CTGAACAAGAAGTGGAGAGTTCATCTGTAAAATTAAATATTTCTTCAAAAGACAACAGAGGAGGTATTAA ATCAAAAACTACAGCTAAAGTAACAAAAGAATTATATGTTAAACTCACTCCTGTTTCCCTTTCTAATTCC CCAATTAAAGGTGCTGATTGTCAGGAAGTTCCACAAGATAAAGATGGCTATAAAAGTTGTGGTCTGAACC CCAAGTTAGAGAAATGTGGACTTGGACAGGAAAACAGTGATAATGAGCATTTGGTTGAAAATGAAGTTTC ATTACTTTTAGAGGAATCTGATCTTCGAAGATCCCCACGTGTAAAGACTACACCCTTGAGGCGACCGACA GAAACTAACCCTGTAACATCTAATTCAGATGAAGAATGTAATGAAACAGTTAAGGAGAAACAAAAACTAT CAGTTCCAGTGAGAAAAAAGGATAAGCGTAATTCTTCTGACAGTGCTATAGATAATCCTAAGCCTAATAA ATTGCCAAAATCTAAGCAATCAGAGACTGTGGATCAAAATTCAGATTCTGATGAAATGCTAGCAATCCTC AAAGAGGTGAGCAGGATGAGTCACAGTTCTTCTTCAGATACTGATATTAATGAAATTCATACAAACCATA AGACTTTGTATGATTTAAAGACTCAGGCGGGGAAAGATGATAAAGGAAAAAGGAAACGAAAAAGTTCTAC ATCTGGCTCAGATTTTGATACTAAAAAGGGCAAATCAGCTAAGAGCTCTATAATTTCTAAAAAGAAACGA CAAACCCAGTCTGAGTCTTCTAATTATGACTCAGAATTAGAAAAAGAGATAAAGAGCATGAGTAAAATTG GTGCTGCCAGAACCACCAAAAAAAGAATTCCAAATACAAAAGATTTTGACTCTTCTGAAGATGAGAAACA CAGCAAAAAAGGAATGGATAATCAAGGGCACAAAAATTTGAAGACCTCACAAGAAGGATCATCTGATGAT GCTGAAAGAAAACAAGAGAGAGAGACTTTCTCTTCAGCAGAAGGCACAGTTGATAAAGACACGACCATCA TGGAATTAAGAGATCGACTTCCTAAGAAGCAGCAAGCAAGTGCTTCCACTGATGGTGTCGATAAGCTTTC TGGGAAAGAGCAGAGTTTTACTTCTTTGGAAGTTAGAAAAGTTGCTGAAACTAAAGAAAAGAGCAAGCAT CTCAAAACCAAAACATGTAAAAAAGTACAGGATGGCTTATCTGATATTGCAGAGAAATTCCTAAAGAAAG ACCAGAGCGATGAAACTTCTGAAGATGATAAAAAGCAGAGCAAAAAGGGAACTGAAGAAAAAAAGAAACC TTCAGACTTTAAGAAAAAAGTAATTAAAATGGAACAACAGTATGAATCTTCATCTGATGGCACTGAAAAG TTACCTGAGCGAGAAGAAATTTGTCATTTTCCTAAGGGCATAAAACAAATTAAGAATGGAACAACTGATG GAGAAAAGAAAAGTAAAAAAATAAGAGATAAAACTTCTAAAAAGAAGGATGAATTATCTGATTATGCTGA GAAGTCAACAGGGAAAGGAGATAGTTGTGACTCTTCAGAGGATAAAAAGAGTAAGAATGGAGCATATGGT AGAGAGAAGAAAAGGTGCAAGTTGCTTGGAAAGAGTTCAAGGAAGAGACAAGATTGTTCATCATCTGATA CTGAGAAATATTCCATGAAAGAAGATGGTTGTAACTCTTCTGATAAGAGACTGAAAAGAATAGAATTGAG GGAAAGAAGAAATTTAAGTTCAAAGAGAAATACTAAGGAAATACAAAGTGGCTCATCATCATCTGATGCT GAGGAAAGTTCTGAAGATAATAAAAAGAAGAAGCAAAGAACTTCATCTAAAAAGAAGGCAGTCATTGTCA AGGAGAAAAAGAGAAACTCCCTAAGAACAAGCACTAAAAGGAAGCAAGCTGACATTACATCCTCATCTTC TTCTGATATAGAAGATGATGATCAGAATTCTATAGGTGAGGGAAGCAGCGATGAACAGAAAATTAAGCCT GTGACTGAAAATTTAGTGCTGTCTTCACATACTGGATTTTGCCAATCTTCAGGAGATGAAGCCTTATCTA AATCAGTGCCTGTCACAGTGGATGATGATGATGACGACAATGATCCTGAGAATAGAATTGCCAAGAAGAT GCTTTTAGAAGAAATTAAAGCCAATCTTTCCTCTGATGAGGATGGATCTTCAGATGATGAGCCAGAAGAA GGGAAAAAAAGAACTGGAAAACAAAATGAAGAAAACCCAGGAGATGAGGAAGCAAAAAATCAAGTCAATT CTGAATCAGATTCAGATTCTGAAGAATCTAAGAAGCCAAGATACAGACATAGGCTTTTGCGGCACAAATT GACTGTGAGTGACGGAGAATCTGGAGAAGAAAAAAAGACAAAGCCTAAAGAGCATAAAGAAGTCAAAGGC AGAAACAGAAGAAAGGTGAGCAGTGAAGATTCAGAAGATTCTGATTTTCAGGAATCAGGAGTTAGTGAAG AAGTTAGTGAATCCGAAGATGAACAGCGGCCCAGAACAAGGTCTGCAAAGAAAGCAGAGTTGGAAGAAAA TCAGCGGAGCTATAAACAGAAAAAGAAAAGGCGACGTATTAAGGTTCAAGAAGATTCATCCAGTGAAAAC AAGAGTAATTCTGAGGAAGAAGAGGAGGAAAAAGAAGAGGAGGAGGAAGAGGAGGAGGAGGAGGAAGAGG AGGAGGAAGATGAAAATGATGATTCCAAGTCTCCTGGAAAAGGCAGAAAGAAAATTCGGAAGATTCTTAA AGATGATAAACTGAGAACAGAAACACAAAATGCTCTTAAGGAAGAGGAAGAGAGACGAAAACGTATTGCT GAGAGGGAGCGTGAGCGAGAAAAATTGAGAGAGGTGATAGAAATTGAAGATGCTTCACCCACCAAGTGTC CAATAACAACCAAGTTGGTTTTAGATGAAGATGAAGAAACCAAAGAACCTTTAGTGCAGGTTCATAGAAA TATGGTTATCAAATTGAAACCCCATCAAGTAGATGGTGTTCAGTTTATGTGGGATTGCTGCTGTGAGTCT GTGAAAAAAACAAAGAAATCTCCAGGTTCAGGATGCATTCTTGCCCACTGTATGGGCCTTGGTAAGACTT TACAGGTGGTAAGTTTTCTTCATACAGTTCTTTTGTGTGACAAACTGGATTTCAGCACGGCGTTAGTGGT TTGTCCTCTTAATACTGCTTTGAATTGGATGAATGAATTTGAGAAGTGGCAAGAGGGATTAAAAGATGAT GAGAAGCTTGAGGTTTCTGAATTAGCAACTGTGAAACGTCCTCAGGAGAGAAGCTACATGCTGCAGAGGT GGCAAGAAGATGGTGGTGTTATGATCATAGGCTATGAGATGTATAGAAATCTTGCTCAAGGAAGGAATGT GAAGAGTCGGAAACTTAAAGAAATATTTAACAAAGCTTTGGTTGATCCAGGCCCTGATTTTGTTGTTTGT GATGAAGGCCATATTCTAAAAAATGAAGCATCTGCTGTTTCTAAAGCTATGAATTCTATACGATCAAGGA GGAGGATTATTTTAACAGGAACACCACTTCAAAATAACCTAATTGAGTATCATTGTATGGTTAATTTTAT CAAGGAAAATTTACTTGGATCCATTAAGGAGTTCAGGAATAGATTTATAAATCCAATTCAAAATGGTCAG TGTGCAGATTCTACCATGGTAGATGTCAGAGTGATGAAAAAACGTGCTCACATTCTCTATGAGATGTTAG CTGGATGTGTTCAGAGGAAAGATTATACAGCATTAACAAAATTCTTGCCTCCAAAACACGAATATGTGTT AGCTGTGAGAATGACTTCTATTCAGTGCAAGCTCTATCAGTACTACTTAGATCACTTAACAGGTGTGGGC AATAATAGTGAAGGTGGAAGAGGAAAGGCAGGTGCAAAGCTTTTCCAAGATTTTCAGATGTTAAGTAGAA TATGGACTCATCCTTGGTGTTTGCAGCTAGACTACATTAGCAAAGAAAATAAGGGTTATTTTGATGAAGA CAGTATGGATGAATTTATAGCCTCAGATTCTGATGAAACCTCCATGAGTTTAAGCTCCGATGATTATACA AAAAAGAAGAAAAAAGGGAAAAAGGGGAAAAAAGATAGTAGCTCAAGTGGAAGTGGCAGTGACAATGATG TTGAAGTGATTAAGGTCTGGAATTCAAGATCTCGGGGAGGTGGTGAAGGAAATGTGGATGAAACAGGAAA CAATCCTTCTGTTTCTTTAAAACTGGAAGAAAGTAAAGCTACTTCTTCTTCTAATCCAAGCAGCCCAGCT CCAGACTGGTACAAAGATTTTGTTACAGATGCTGATGCTGAGGTTTTAGAGCATTCTGGGAAAATGGTAC TTCTCTTTGAAATTCTTCGAATGGCAGAGGAAATTGGGGATAAAGTCCTTGTTTTCAGCCAGTCCCTCAT ATCTCTGGACTTGATTGAAGATTTTCTTGAATTAGCTAGTAGGGAGAAGACAGAAGATAAAGATAAACCC CTTATTTATAAAGGTGAGGGGAAGTGGCTTCGAAACATTGACTATTACCGTTTAGATGGTTCCACTACTG CACAGTCAAGGAAGAAGTGGGCTGAAGAATTTAATGATGAAACTAATGTGAGAGGACGATTATTTATCAT TTCTACTAAAGCAGGATCTCTAGGAATTAATCTGGTAGCTGCTAATCGAGTAATTATATTCGACGCTTCT TGGAATCCATCTTATGACATCCAGAGTATATTCAGAGTTTATCGCTTTGGACAAACTAAGCCTGTTTATG TATATAGGTTCTTAGCTCAGGGAACCATGGAAGATAAGATTTATGATCGGCAAGTAACTAAGCAGTCACT GTCTTTTCGAGTTGTTGATCAGCAGCAGGTGGAGCGTCATTTTACTATGAATGAGCTTACTGAACTTTAT ACTTTTGAGCCAGACTTATTAGATGACCCTAATTCAGAAAAGAAGAAGAAGAGGGATACTCCCATGCTGC CAAAGGATACCATACTTGCAGAGCTCCTTCAGATACATAAAGAACACATTGTAGGATACCATGAACATGA TTCTCTTTTGGACCACAAAGAAGAAGAAGAGTTGACTGAAGAAGAAAGAAAAGCAGCTTGGGCTGAGTAT GAAGCAGAGAAGAAGGGACTGACCATGCGTTTCAACATACCAACTGGGACCAATTTACCCCCTGTCAGTT TCAACTCTCAAACTCCTTATATTCCTTTCAATTTGGGAGCCCTGTCAGCAATGAGTAATCAACAGCTGGA GGACCTCATTAATCAAGGAAGAGAAAAAGTTGTAGAAGCAACAAACAGTGTGACAGCAGTGAGGATTCAA CCTCTTGAGGATATAATTTCAGCTGTATGGAAGGAGAACATGAATCTCTCAGAGGCCCAAGTACAGGCGT TAGCATTAAGTAGACAAGCCAGCCAGGAGCTTGATGTTAAACGAAGAGAAGCAATCTACAATGATGTATT GACAAAACAACAGATGTTAATCAGCTGTGTTCAGCGAATACTTATGAACAGAAGGCTCCAGCAGCAGTAC AATCAGCAGCAACAGCAACAAATGACTTATCAACAAGCAACACTGGGTCACCTCATGATGCCAAAGCCCC CAAATTTGATCATGAATCCTTCTAACTACCAGCAGATTGATATGAGAGGAATGTATCAGCCAGTGGCTGG TGGTATGCAGCCACCACCATTACAGCGTGCACCACCCCCAATGAGAAGCAAAAATCCAGGACCTTCCCAA GGGAAATCAATG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC219519 representing NM_138270
Red=Cloning site Green=Tags(s) MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEK SKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKEDGLHGIVSCTACGQQV NHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNL GRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPK KTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATK LRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDIS KSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDI FENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNS PIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPT ETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAIL KEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKR QTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDD AERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKH LKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEK LPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYG REKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDA EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP VTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKG RNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN KSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIA EREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCES VKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDD EKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVC DEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQ CADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVG NNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYT KKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPA PDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKP LIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDAS WNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELY TFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEY EAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQ PLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQY NQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPGPSQ GKSM TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_138270 |
ORF Size | 7362 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_138270.2 |
RefSeq Size | 11124 bp |
RefSeq ORF | 7365 bp |
Locus ID | 546 |
UniProt ID | P46100 |
Domains | SNF2_N, DEAD, helicase_C |
Protein Families | Druggable Genome, Transcription Factors |
MW | 407.9 kDa |
Gene Summary | The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2017] |
Documents
Product Manuals |
FAQs |
SDS |