SEC24B (NM_006323) Human Tagged ORF Clone
CAT#: RC211593
- TrueORF®
SEC24B (Myc-DDK-tagged)-Human SEC24 family, member B (S. cerevisiae) (SEC24B), transcript variant 1
ORF Plasmid: tGFP
"NM_006323" in other vectors (4)
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CNY 12,640.00
Cited in 1 publication. |
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | SEC24 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC211593 representing NM_006323
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCGGCCCCCGCCGGGTCCTCTCACCCGGCCGCCAGCGCCCGGATCCCGCCCAAGTTCGGCGGATCGG CCGTCTCAGGAGCCGCAGCGCCCGCGGGCCCGGGTGCGGGCCCGGCGCCGCACCAGCAGAACGGTCCAGC CCAGAATCAAATGCAGGTTCCATCTGGATATGGATTGCATCATCAAAACTATATTGCTCCCTCAGGACAT TACTCTCAAGGACCTGGGAAAATGACCTCATTGCCATTGGATACCCAGTGTGGTGATTACTACTCTGCTC TCTATACAGTACCAACACAAAATGTGACTCCTAACACAGTGAACCAGCAACCAGGAGCACAGCAGTTGTA CAGCAGGGGTCCTCCTGCCCCTCATATTGTGGGATCCACTCTAGGATCTTTCCAAGGTGCTGCATCGTCA GCATCCCATTTGCATACGAGTGCCTCCCAACCATACTCCTCTTTTGTGAATCACTACAATAGTCCAGCCA TGTACTCTGCCAGCTCTTCTGTTGCGTCTCAGGGATTTCCCTCTACTTGTGGTCATTATGCTATGTCAAC TGTTTCTAATGCCGCGTATCCTAGTGTTTCATATCCCTCTCTGCCTGCTGGTGATACATATGGGCAAATG TTTACCTCACAGAATGCTCCGACTGTTAGGCCAGTTAAAGATAATTCATTCTCTGGTCAAAATACAGCTA TCAGCCATCCATCGCCACTTCCACCTCTACCATCACAACAGCACCACCAGCAGCAAAGTCTTTCAGGATA CAGTACTCTAACGTGGTCATCTCCAGGCCTTCCATCGACTCAAGACAATCTCATCCGAAACCACACAGGA TCCCTGGCTGTAGCGAACAACAACCCAACCATTACTGTTGCAGATTCTTTATCCTGTCCTGTTATGCAAA ATGTTCAGCCTCCCAAGTCCAGCCCAGTGGTATCCACTGTTTTATCAGGATCCTCAGGATCCTCATCAAC AAGAACACCTCCCACTGCAAATCACCCAGTTGAGCCTGTGACCTCAGTTACACAGCCATCAGAGCTATTA CAACAAAAAGGCGTGCAGTATGGTGAATATGTTAATAACCAAGCTAGCTCCGCACCAACTCCCTTGTCAT CAACTTCCGATGATGAGGAAGAGGAGGAGGAGGATGAGGAAGCAGGTGTTGACAGCTCTTCTACCACAAG CAGTGCTTCTCCAATGCCCAACAGTTATGATGCCCTGGAAGGAGGCAGTTACCCAGATATGCTTTCTTCA TCAGCAAGCAGTCCTGCTCCTGATCCCGCCCCTGAACCTGATCCTGCTTCTGCTCCAGCTCCAGCTTCAG CTCCAGCTCCTGTCGTCCCTCAGCCTTCAAAAATGGCTAAGCCTTTGGCTATGGCTATCCAACACTTCAG CCTGGTTATCAGAATGCTACAGCACCACTTATTTCTGGAGTACAGCCCCAGTAACCCGGTATATTCTGGA TTCCAGCAGTATCCTCAACAGTATCCTGGTGTGAACCAGCTATCCTCCAGTATAGGAGGATTGAGTCTTC AGAGTTCTCCACAACCAGAAAGCCTGAGACCTGTAAACCTTACTCAGGAGAGGAATATTTTACCTATGAC TCCTGTTTGGGCTCCTGTACCTAACTTGAATGCAGACCTCAAAAAATTAAACTGTAGCCCAGATTCATTT CGGTGTACTTTGACAAATATTCCACAGACACAGGCTTTACTGAATAAAGCTAAGCTTCCTTTAGGATTGT TGTTACATCCCTTCAGAGACCTAACGCAATTACCAGTGATAACATCAAATACCATTGTGAGGTGCCGATC CTGTCGAACGTATATTAACCCCTTTGTATCCTTCATTGATCAACGTAGATGGAAATGCAATTTGTGCTAT AGAGTAAACGATGTTCCTGAAGAATTTATGTATAACCCCCTTACCCGATCTTATGGAGAGCCTCATAAAC GACCAGAAGTTCAGAATTCAACTGTGGAGTTCATTGCTTCTTCAGATTACATGCTGCGTCCTCCTCAACC TGCAGTTTACTTGTTTGTTTTAGATGTGTCTCATAATGCAGTGGAAGCTGGATATTTGACAATTTTGTGC CAGTCACTCCTAGAAAATCTAGACAAGCTTCCTGGAGATTCACGAACAAGAATAGGATTCATGACCTTTG ATAGCACTATTCATTTCTACAATTTACAAGAAGGATTATCACAGCCTCAAATGTTGATTGTGTCTGATAT AGATGATGTTTTTCTACCTACACCGGATAGTTTACTTGTGAATCTATATGAAAGTAAAGAGCTTATAAAA GACTTACTGAATGCATTACCAAACATGTTCACCAATACAAGAGAAACACACAGTGCCCTTGGTCCTGCAC TTCAGGCTGCCTTTAAATTAATGTCTCCAACAGGTGGCCGTGTGTCTGTATTTCAGACACAGTTACCTTC CTTGGGTGCAGGACTTCTGCAATCCAGAGAAGATCCTAATCAGAGATCAAGTACAAAGGTGGTACAACAT CTTGGCCCTGCAACTGATTTTTATAAGAAACTTGCATTAGATTGCTCGGGACAGCAAACTGCAGTGGATT TGTTCCTTTTAAGTTCACAGTATTCTGATCTTGCTTCTCTAGCTTGCATGTCCAAGTATTCTGCAGGGTG CATCTATTATTATCCATCATTCCACTATACTCACAATCCTTCACAAGCAGAAAAGTTACAAAAAGACCTA AAACGGTATCTCACAAGAAAAATTGGGTTTGAAGCTGTTATGAGAATAAGGTGTACTAAAGGTCTTTCAA TGCACACTTTTCACGGTAACTTCTTTGTCCGTTCTACTGATTTGTTATCCCTTGCCAACATCAATCCTGA TGCTGGATTTGCGGTGCAGTTGTCAATTGAAGAAAGTTTAACAGATACTTCCTTAGTATGTTTTCAAACA GCCCTATTATATACATCAAGCAAAGGTGAGCGGAGAATTAGAGTACATACACTTTGTTTGCCAGTGGTAA GTTCACTAGCAGATGTATATGCGGGAGTGGATGTACAAGCTGCCATCTGCCTTCTGGCAAACATGGCTGT GGATCGGTCCGTTTCATCAAGTCTGTCAGATGCAAGAGATGCCTTAGTGAATGCTGTAGTGGACTCATTG TCTGCATATGGCTCAACTGTCTCAAATTTACAGCACTCTGCATTGATGGCGCCCAGCTCCCTCAAGTTGT TTCCTCTCTATGTTTTGGCCCTTCTCAAACAGAAAGCATTTAGAACGGGTACAAGCACACGGCTGGATGA TCGTGTATATGCCATGTGTCAGATAAAGTCTCAGCCACTTGTTCATCTAATGAAAATGATTCATCCCAAC TTATACAGGATAGACAGATTGACAGATGAGGGTGCAGTACATGTTAATGACAGGATTGTACCACAGCCAC CTCTTCAAAAATTGTCTGCAGAGAAGCTGACAAGAGAAGGTGCTTTCCTTATGGACTGTGGCTCTGTTTT TTACATTTGGGTTGGGAAAGGCTGTGACAATAACTTCATAGAGGATGTGCTTGGATATACTAATTTTGCA TCAATACCACAGAAAATGACACATCTTCCAGAGCTAGATACACTTTCATCAGAAAGAGCCAGATCCTTCA TAACTTGGCTTAGAGACAGCAGACCATTAAGTCCAATCCTTCACATAGTAAAAGATGAGAGTCCTGCCAA AGCAGAATTTTTTCAGCATTTGATTGAAGACCGGACAGAGGCTGCATTTTCTTACTATGAATTTTTGCTT CATGTTCAGCAGCAGATTTGTAAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC211593 representing NM_006323
Red=Cloning site Green=Tags(s) MSAPAGSSHPAASARIPPKFGGSAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSGH YSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASS ASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQM FTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTG SLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELL QQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSS SASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPLAMAIQHFSLVIRMLQHHLFLEYSPSNPVYSG FQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPDSF RCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCRSCRTYINPFVSFIDQRRWKCNLCY RVNDVPEEFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILC QSLLENLDKLPGDSRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIK DLLNALPNMFTNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQH LGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDL KRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLVCFQT ALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSL SAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPN LYRIDRLTDEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFA SIPQKMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLL HVQQQICK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_006323 |
ORF Size | 3804 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_006323.1, NP_006314.1 |
RefSeq Size | 4758 bp |
RefSeq ORF | 3807 bp |
Locus ID | 10427 |
UniProt ID | O95487 |
Domains | zf-Sec23_Sec24, Sec23_trunk, Sec23_helical, Gelsolin |
MW | 137.2 kDa |
Gene Summary | The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein is thought to be a cargo-binding component of the COPII vesicle, and is thought to be involved in the transport of secretory proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in this gene have been associated with neural tube defects, and are thought to be a result of a disruption in interactions with the protein encoded by the VANGL planar cell polarity protein 2 (VANGL2) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Mutations in the COPII vesicle component gene SEC24B are associated with human neural tube defects.
,null,
Human mutation
,PubMed ID 23592378
[SEC24B]
|
Documents
Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC211593L3 | Lenti-ORF clone of SEC24B (Myc-DDK-tagged)-Human SEC24 family, member B (S. cerevisiae) (SEC24B), transcript variant 1 |
CNY 14,540.00 |
|
RC211593L4 | Lenti-ORF clone of SEC24B (mGFP-tagged)-Human SEC24 family, member B (S. cerevisiae) (SEC24B), transcript variant 1 |
CNY 14,540.00 |
|
RG211593 | SEC24B (tGFP-tagged) - Human SEC24 family, member B (S. cerevisiae) (SEC24B), transcript variant 1 |
CNY 11,312.00 |
|
SC116223 | SEC24B (untagged)-Human SEC24 family, member B (S. cerevisiae) (SEC24B), transcript variant 1 |
CNY 8,840.00 |