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ABCD2 (NM_005164) Human Tagged ORF Clone
CAT＃: RC211199
ABCD2 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2)
ORF Plasmid: tGFP
"NM_005164" in other vectors (6)
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CNY 5,424.00
CNY 5,800.00
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | ABC39; ALDL1; ALDR; ALDRP; hALDR |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC211199 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACACATATGCTAAATGCAGCAGCTGATCGAGTGAAATGGACCAGATCGAGTGCTGCTAAGAGGGCTG CCTGCCTGGTGGCTGCGGCATATGCTCTGAAAACCCTCTATCCCATCATTGGCAAGCGTTTAAAGCAATC TGGCCACGGGAAGAAAAAAGCAGCAGCTTACCCTGCTGCAGAGAACACAGAAATACTGCATTGCACCGAG ACCATTTGTGAAAAACCTTCGCCTGGAGTGAATGCAGATTTCTTCAAACAGCTACTAGAACTTCGGAAAA TTTTGTTTCCAAAACTTGTGACCACTGAAACAGGGTGGCTCTGCCTGCACTCAGTGGCTCTAATCTCAAG AACCTTTCTTTCTATCTATGTGGCTGGTCTGGATGGAAAAATCGTGAAAAGCATTGTGGAAAAGAAGCCT CGGACTTTCATCATCAAATTAATCAAGTGGCTTATGATTGCCATCCCTGCTACCTTCGTCAACAGTGCAA TAAGGTACCTGGAATGCAAATTGGCTTTGGCCTTCAGAACTCGCCTAGTAGACCACGCCTATGAAACCTA TTTTACAAATCAGACTTATTATAAAGTGATCAATATGGATGGGAGGCTGGCAAACCCTGACCAATCTCTT ACGGAGGATATTATGATGTTCTCCCAATCTGTGGCTCACTTGTATTCCAATCTGACCAAACCTATTTTAG ATGTAATGCTGACCTCCTATACACTCATTCAAACTGCTACATCCAGAGGAGCAAGCCCAATTGGGCCCAC CCTACTAGCAGGACTTGTGGTGTATGCCACTGCTAAAGTGTTAAAAGCCTGTTCTCCCAAATTTGGCAAA CTGGTGGCAGAGGAAGCACATAGAAAAGGCTATTTGCGGTATGTGCACTCGAGAATTATAGCCAATGTAG AAGAAATTGCCTTTTACAGAGGACATAAGGTAGAAATGAAACAACTTCAGAAAAGTTACAAAGCTTTAGC AGATCAGATGAACCTCATTTTATCCAAACGTTTGTGGTACATCATGATAGAACAGTTCCTGATGAAGTAT GTTTGGAGCAGCAGTGGACTAATTATGGTGGCTATACCTATTATCACTGCAACTGGCTTTGCAGATGGTG AGGATGGCCAAAAGCAAGTTATGGTTAGTGAACGGACAGAAGCCTTTACCACTGCTCGAAATTTACTGGC CTCTGGAGCTGATGCTATTGAAAGGATTATGTCTTCATACAAAGAGGTCACTGAATTAGCAGGCTACACT GCTCGAGTGTACAATATGTTTTGGGTCTTTGATGAAGTAAAAAGAGGCATTTATAAGAGAACTGCTGTCA TTCAAGAATCTGAAAGCCATAGCAAGAATGGAGCTAAGGTAGAATTACCTCTCAGTGACACATTGGCAAT TAAAGGAAAAGTTATTGATGTGGATCACGGAATTATTTGTGAAAATGTTCCCATAATTACACCAGCAGGA GAAGTGGTGGCTTCCAGGCTAAACTTCAAAGTAGAAGAAGGAATGCATCTTTTGATAACTGGTCCCAATG GTTGTGGGAAAAGTTCTCTCTTCAGAATTCTAAGTGGGCTCTGGCCTGTGTATGAAGGAGTCCTCTATAA ACCACCTCCTCAACATATGTTTTATATTCCACAAAGGCCATATATGTCTCTTGGAAGTCTTCGGGATCAA GTCATTTACCCTGATTCAGTGGATGATATGCATGATAAAGGTTATACAGACCAAGATCTGGAACGTATCC TACACAATGTCCATCTCTATCACATAGTTCAAAGAGAAGGAGGATGGGATGCTGTTATGGACTGGAAAGA TGTCCTGTCAGGAGGGGAAAAGCAAAGAATGGGCATGGCTCGTATGTTTTATCATAAACCAAAATATGCC TTGCTGGATGAATGTACCAGTGCTGTCAGCATTGATGTCGAAGGAAAGATATTTCAGGCTGCAAAAGGGG CTGGAATTTCCTTACTGTCTATAACACACAGACCTTCTCTTTGGAAATACCACACACATTTATTACAGTT TGATGGTGAAGGAGGTTGGCGCTTTGAACAATTGGATACTGCTATCCGTTTGACATTGAGTGAAGAAAAA CAAAAGCTAGAATCTCAGCTAGCTGGAATTCCCAAAATGCAGCAGAGACTCAATGAACTATGTAAAATTT TGGGAGAAGACTCAGTGCTGAAAACAATTAAAAATGAAGATGAGACATCT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC211199 protein sequence
Red=Cloning site Green=Tags(s) MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAAENTEILHCTE TICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKP RTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMDGRLANPDQSL TEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGK LVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKY VWSSSGLIMVAIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT ARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAG EVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQ VIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYA LLDECTSAVSIDVEGKIFQAAKGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEK QKLESQLAGIPKMQQRLNELCKILGEDSVLKTIKNEDETS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_005164 |
| ORF Size | 2220 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005164.4 |
| RefSeq Size | 5341 bp |
| RefSeq ORF | 2223 bp |
| Locus ID | 225 |
| UniProt ID | Q9UBJ2 |
| Domains | ABC_tran, AAA |
| Protein Families | Druggable Genome |
| Protein Pathways | ABC transporters |
| MW | 83.2 kDa |
| Gene Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211199L1 | Lenti ORF clone of Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), Myc-DDK-tagged |
CNY 7,824.00 |
|
| RC211199L2 | Lenti ORF clone of Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), mGFP tagged |
CNY 7,700.00 |
|
| RC211199L3 | Lenti ORF clone of Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), Myc-DDK-tagged |
CNY 7,824.00 |
|
| RC211199L4 | Lenti ORF clone of Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), mGFP tagged |
CNY 7,824.00 |
|
| RG211199 | ABCD2 (tGFP-tagged) - Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2) |
CNY 7,024.00 |
|
| SC310135 | ABCD2 (untagged)-Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2) |
CNY 7,220.00 |
