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SOCS5 (NM_144949) Human Tagged ORF Clone
CAT＃: RC206267
SOCS5 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2
ORF Plasmid: tGFP
"NM_144949" in other vectors (4)
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CNY 3,992.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CIS6; Cish5; CISH6; SOCS-5 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC206267 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATAAAGTGGGAAAAATGTGGAATAACTTCAAATACAGGTGTCAGAATCTCTTCGGTCATGAGGGAG GAAGCCGTAGTGAAAATGTGGACATGAACTCCAACAGATGTTTGTCTGTCAAAGAGAAAAACATCAGCAT AGGAGACTCAACTCCTCAGCAACAAAGCAGTCCCTTAAGAGAAAATATTGCCTTACAACTGGGATTAAGC CCTTCGAAGAATTCTTCAAGGAGAAATCAAAATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCA TCGAAAAGGATAATGATTCTTGTGTTACGCCAGGAACAAGACTTGCACGAAGAGATTCCTACTCTCGACA TGCTCCATGGGGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTTCATTGGATGCTGATAAA AAGTTTGGTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGCGCTACGGCGTAAGTTCTGTACACGACA TGGACAGTGTTTCCAGCAGAACTGTAGGAAGTCGCTCTCTAAGACAGAGGTTGCAGGATACTGTGGGCTT GTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCTCTCTTTTCCAATAAAAGAAAAATCCATCTC TCTGAATTAATGCTTGAGAAATGCCCTTTTCCTGCTGGCTCAGATTTAGCCCAAAAATGGCATTTGATTA AACAGCATACAGCTCCTGTGAGCCCACATTCAACATTTTTTGATACATTTGATCCATCTTTGGTTTCTAC AGAAGATGAAGAAGATAGGCTTAGAGAGAGAAGGCGGCTTAGTATTGAAGAAGGGGTTGATCCCCCTCCC AATGCACAAATACATACATTTGAAGCTACTGCACAGGTTAATCCATTATATAAACTGGGACCAAAATTAG CTCCTGGAATGACTGAAATAAGTGGGGACAGTTCTGCAATTCCACAAGCTAATTGTGACTCGGAAGAGGA TACAACCACCCTGTGTTTGCAGTCACGGAGGCAGAAGCAGCGTCAGATATCTGGAGACAGCCATACCCAT GTTAGCAGACAGGGAGCTTGGAAAGTCCACACACAGATTGATTACATACACTGCCTCGTGCCTGATTTGC TTCAAATTACAGGGAATCCCTGTTACTGGGGAGTGATGGACCGTTATGAAGCAGAAGCCCTTCTCGAAGG GAAACCTGAAGGCACGTTTTTGCTCAGGGACTCTGCGCAAGAGGACTACCTCTTCTCTGTGAGCTTCCGC CGCTACAACAGATCCCTGCATGCCCGAATTGAGCAGTGGAATCACAACTTTAGTTTCGACGCCCATGACC CGTGTGTATTTCACTCCTCCACTGTAACGGGACTTTTAGAACATTATAAAGATCCCAGTTCGTGCATGTT TTTTGAACCATTGCTTACTATATCACTAAATATGACTTTCCCTTTTAGCCTGCAGTATATCTGTCGCGCG GTAATCTGCAGGTGCACTACGTATGATGGAATTGATGGGCTCCCTCTACCCTCAATGTTACAGGATTTTT TAAAAGAGTATCATTATAAACAAAAAGTTAGAGTTCGCTGGTTGGAACGAGAACCAGTCAAGGCAAAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC206267 protein sequence
Red=Cloning site Green=Tags(s) MDKVGKMWNNFKYRCQNLFGHEGGSRSENVDMNSNRCLSVKEKNISIGDSTPQQQSSPLRENIALQLGLS PSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGGKKKHSCSTKTQSSLDADK KFGRTRSGLQRRERRYGVSSVHDMDSVSSRTVGSRSLRQRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHL SELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPP NAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDSSAIPQANCDSEEDTTTLCLQSRRQKQRQISGDSHTH VSRQGAWKVHTQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFR RYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNMTFPFSLQYICRA VICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_144949 |
| ORF Size | 1608 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_144949.3 |
| RefSeq Size | 4510 bp |
| RefSeq ORF | 1611 bp |
| Locus ID | 9655 |
| UniProt ID | O75159 |
| Domains | SH2, SOCS |
| Protein Families | Druggable Genome |
| Protein Pathways | Jak-STAT signaling pathway |
| MW | 61.2 kDa |
| Gene Summary | The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The genetic effect and molecular function of the SOCS5 in the prognosis of esophageal squamous cell carcinoma
,null,
Journal of Cancer
,PubMed ID 33758600
[SOCS5]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206267L3 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206267L4 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG206267 | SOCS5 (tGFP-tagged) - Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2 |
CNY 5,592.00 |
|
| SC124288 | SOCS5 (untagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 2 |
CNY 4,000.00 |
