GPR91 (SUCNR1) (NM_033050) Human Tagged ORF Clone
CAT#: RC205888
SUCNR1 (Myc-DDK-tagged)-Human succinate receptor 1 (SUCNR1)
ORF Plasmid: tGFP
"NM_033050" in other vectors (6)
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CNY 3,656.00
CNY 3,990.00
Cited in 2 publications. |
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | GPR91 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC205888 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTGGGGATCATGGCATGGAATGCAACTTGCAAAAACTGGCTGGCAGCAGAGGCTGCCCTGGAAAAGT ACTACCTTTCCATTTTTTATGGGATTGAGTTCGTTGTGGGAGTCCTTGGAAATACCATTGTTGTTTACGG CTACATCTTCTCTCTGAAGAACTGGAACAGCAGTAATATTTATCTCTTTAACCTCTCTGTCTCTGACTTA GCTTTTCTGTGCACCCTCCCCATGCTGATAAGGAGTTATGCCAATGGAAACTGGATATATGGAGACGTGC TCTGCATAAGCAACCGATATGTGCTTCATGCCAACCTCTATACCAGCATTCTCTTTCTCACTTTTATCAG CATAGATCGATACTTGATAATTAAGTATCCTTTCCGAGAACACCTTCTGCAAAAGAAAGAGTTTGCTATT TTAATCTCCTTGGCCATTTGGGTTTTAGTAACCTTAGAGTTACTACCCATACTTCCCCTTATAAATCCTG TTATAACTGACAATGGCACCACCTGTAATGATTTTGCAAGTTCTGGAGACCCCAACTACAACCTCATTTA CAGCATGTGTCTAACACTGTTGGGGTTCCTTATTCCTCTTTTTGTGATGTGTTTCTTTTATTACAAGATT GCTCTCTTCCTAAAGCAGAGGAATAGGCAGGTTGCTACTGCTCTGCCCCTTGAAAAGCCTCTCAACTTGG TCATCATGGCAGTGGTAATCTTCTCTGTGCTTTTTACACCCTATCACGTCATGCGGAATGTGAGGATCGC TTCACGCCTGGGGAGTTGGAAGCAGTATCAGTGCACTCAGGTCGTCATCAACTCCTTTTACATTGTGACA CGGCCTTTGGCCTTTCTGAACAGTGTCATCAACCCTGTCTTCTATTTTCTTTTGGGAGATCACTTCAGGG ACATGCTGATGAATCAACTGAGACACAACTTCAAATCCCTTACATCCTTTAGCAGATGGGCTCATGAACT CCTACTTTCATTCAGAGAAAAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC205888 protein sequence
Red=Cloning site Green=Tags(s) MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDL AFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAI LISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKI ALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVT RPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_033050 |
ORF Size | 1002 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_033050.6 |
RefSeq Size | 1650 bp |
RefSeq ORF | 1005 bp |
Locus ID | 56670 |
UniProt ID | Q9BXA5 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
MW | 38.7 kDa |
Gene Summary | This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling
,Trauelsen, M;Hiron, TK;Lin, D;Petersen, JE;Breton, B;Husted, AS;Hjorth, SA;Inoue, A;Frimurer, TM;Bouvier, M;O'Callaghan, CA;Schwartz, TW;,
Cell reports
,PubMed ID 34133934
[GPR91]
|
Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
,Rexen Ulven, E;Trauelsen, M;Brvar, M;Lückmann, M;Bielefeldt, LØ;Jensen, LKI;Schwartz, TW;Frimurer, TM;,
Sci Rep
,PubMed ID 29968758
[GPR91]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC205888L1 | Lenti ORF clone of Human succinate receptor 1 (SUCNR1), Myc-DDK-tagged |
CNY 6,056.00 |
|
RC205888L2 | Lenti ORF clone of Human succinate receptor 1 (SUCNR1), mGFP tagged |
CNY 5,890.00 |
|
RC205888L3 | Lenti ORF clone of Human succinate receptor 1 (SUCNR1), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC205888L4 | Lenti ORF clone of Human succinate receptor 1 (SUCNR1), mGFP tagged |
CNY 5,890.00 |
|
RG205888 | SUCNR1 (tGFP-tagged) - Human succinate receptor 1 (SUCNR1) |
CNY 5,256.00 |
|
SC123076 | SUCNR1 (untagged)-Human succinate receptor 1 (SUCNR1) |
CNY 3,656.00 |