KLHL2 (NM_007246) Human Tagged ORF Clone
CAT#: RC205347
KLHL2 (Myc-DDK-tagged)-Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 1
ORF Plasmid: tGFP
"NM_007246" in other vectors (6)
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CNY 4,416.00
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | ABP-KELCH; MAV; MAYVEN |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC205347 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGACGCCGCCGCTGCCTCCCGCATGCACAAAGCAGGGTCATCAGAAGCCTCTCGATTCAAAAGATG ATAATACCGAAAAACACTGCCCAGTGACAGTGAATCCTTGGCATATGAAGAAAGCTTTCAAAGTCATGAA CGAATTAAGAAGTCAAAATTTGCTGTGCGATGTCACAATTGTGGCAGAAGACATGGAAATTTCTGCTCAT AGAGTGGTGCTGGCCGCCTGTAGTCCTTATTTTCATGCCATGTTTACAGGTGAGATGAGTGAGAGCCGAG CAAAGAGAGTTAGAATAAAAGAGGTAGATGGCTGGACCCTGAGGATGCTAATTGATTATGTTTACACTGC AGAAATTCAGGTTACAGAAGAAAATGTACAGGTACTTCTCCCAGCAGCTGGTCTCTTACAGTTACAGGAT GTGAAGAAGACTTGTTGTGAATTTTTGGAATCCCAGCTTCACCCTGTCAACTGCTTAGGAATCCGGGCTT TTGCTGATATGCATGCATGTACTGACCTTCTGAACAAGGCCAACACCTATGCAGAGCAACATTTTGCAGA TGTTGTACTTAGTGAAGAATTTCTCAATCTTGGCATCGAACAAGTGTGCAGCTTAATCTCAAGTGACAAA CTTACCATTTCTTCAGAAGAGAAGGTATTTGAAGCAGTAATAGCATGGGTGAACCATGACAAGGATGTGA GGCAAGAGTTTATGGCCCGACTGATGGAACATGTACGGTTACCTTTGCTTCCTCGGGAATATTTAGTTCA GAGGGTTGAAGAGGAAGCATTGGTCAAGAATAGCAGTGCTTGCAAAGATTACCTCATTGAAGCAATGAAG TACCATTTGCTGCCAACAGAGCAGCGTATATTAATGAAGAGTGTCCGGACCCGGCTGAGGACACCCATGA ACCTTCCCAAATTGATGGTGGTGGTTGGGGGCCAAGCACCAAAGGCTATCCGGAGTGTGGAATGCTATGA CTTTAAAGAAGAAAGGTGGCACCAAGTAGCAGAGTTGCCTTCCAGGAGGTGCAGGGCAGGCATGGTCTAC ATGGCTGGACTTGTTTTTGCTGTTGGTGGCTTTAATGGCTCATTAAGAGTTCGCACTGTAGATTCCTACG ACCCTGTGAAGGACCAGTGGACCAGCGTTGCTAACATGAGAGACCGGAGAAGCACTTTGGGAGCTGCTGT GTTAAATGGATTATTATACGCTGTGGGAGGCTTTGATGGGAGTACAGGTTTGTCATCTGTGGAAGCATAC AACATAAAGTCTAATGAGTGGTTTCATGTAGCTCCCATGAATACAAGGAGGAGCAGTGTTGGTGTGGGTG TTGTTGGAGGTTTGCTCTATGCTGTAGGAGGTTATGATGTAGCATCACGTCAGTGTCTTAGCACAGTAGA ATGCTATAATGCTACAACAAATGAGTGGACCTATATAGCAGAAATGAGCACCAGGCGGAGTGGAGCAGGT GTTGGTGTGTTAAACAATTTATTGTATGCTGTAGGAGGTCATGATGGCCCTTTAGTACGAAAAAGTGTTG AAGTATATGATCCCACCACTAACGCATGGAGACAGGTTGCAGATATGAACATGTGCAGAAGAAATGCAGG AGTTTGTGCAGTTAATGGTCTGTTATATGTTGTTGGAGGGGATGATGGTTCCTGTAACTTGGCGTCAGTA GAATATTATAACCCAACAACCGATAAATGGACAGTTGTGTCATCGTGTATGAGCACAGGGAGAAGTTATG CAGGGGTCACAGTTATTGATAAACGATTA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC205347 protein sequence
Red=Cloning site Green=Tags(s) METPPLPPACTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEISAH RVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQD VKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAEQHFADVVLSEEFLNLGIEQVCSLISSDK LTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMK YHLLPTEQRILMKSVRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVY MAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAY NIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDVASRQCLSTVECYNATTNEWTYIAEMSTRRSGAG VGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASV EYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKRL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
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Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_007246 |
ORF Size | 1779 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_007246.2, NP_009177.2 |
RefSeq Size | 3137 bp |
RefSeq ORF | 1782 bp |
Locus ID | 11275 |
UniProt ID | O95198 |
Domains | BTB, Kelch |
MW | 66.1 kDa |
Gene Summary | Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC205347L1 | Lenti ORF clone of Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 1, Myc-DDK-tagged |
CNY 6,816.00 |
|
RC205347L2 | Lenti ORF clone of Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC205347L3 | Lenti ORF clone of Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC205347L4 | Lenti ORF clone of Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RG205347 | KLHL2 (tGFP-tagged) - Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 1 |
CNY 6,016.00 |
|
SC115613 | KLHL2 (untagged)-Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 1 |
CNY 4,424.00 |