TNFAIP8 (NM_014350) Human Tagged ORF Clone
CAT#: RC202729
TNFAIP8 (Myc-DDK-tagged)-Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1
ORF Plasmid: tGFP
"NM_014350" in other vectors (8)
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CNY 2,400.00
CNY 3,705.00
Cited in 5 publications. |
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC202729 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCACTCCGAAGCAGAAGAATCCAAGGAAGTGGCCACAGATGTCTTTAATTCCAAAAACCTGGCCGTTC AGGCACAAAAGAAGATCTTGGGTAAAATGGTGTCCAAATCCATCGCCACCACCTTAATAGACGACACAAG TAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAAAACAAGAAGGAGGCAGAGAAG ATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCCATTCTTTATAGGAATAATCAGTTTAATCAAG ATGAGCTAGCATTGATGGAGAAATTTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCA TCAGGTGGATTATACCTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCAC CAAATCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGTTAATAATGTGTTTGATCATTTTTCAG ATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACTTACAAAAACTATGTGA TGGTATCAACAAAATGTTGGATGAAGAGAACATA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC202729 protein sequence
Red=Cloning site Green=Tags(s) MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEK IIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLH QIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKMLDEENI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_014350 |
ORF Size | 594 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_014350.4 |
RefSeq Size | 2103 bp |
RefSeq ORF | 597 bp |
Locus ID | 25816 |
UniProt ID | O95379 |
Protein Families | Druggable Genome |
MW | 23 kDa |
Gene Summary | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.[UniProtKB/Swiss-Prot Function] |
Citations (5)
The use of this cDNA Clones has been cited in the following citations: |
---|
TNFAIP8 drives metabolic reprogramming to promote prostate cancer cell proliferation.
,null,
The international journal of biochemistry & cell biology
,PubMed ID 33227392
[TNFAIP8]
|
MicroRNA-205-5p inhibits skin cancer cell proliferation and increase drug sensitivity by targeting TNFAIP8
,Ge, X;Niture, S;Lin, M;Cagle, P;Li, PA;Kumar, D;,
Scientific reports
,PubMed ID 33707587
[TNFAIP8]
|
TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation
,Niture, S;Gyamfi, MA;Lin, M;Chimeh, U;Dong, X;Zheng, W;Moore, J;Kumar, D;,
Cell Death Dis
,PubMed ID 32152268
[TNFAIP8]
|
SCC-S2 Facilitates Tumor Proliferation and Invasion via Activating Wnt Signaling and Depressing Hippo Signaling in Colorectal Cancer Cells and Predicts Poor Prognosis of Patients
,Yang, C;Xu, W;Meng, X;Zhou, S;Zhang, M;Cui, D;,
J. Histochem. Cytochem.
,PubMed ID 30216108
[TNFAIP8]
|
TNFAIP8 promotes prostate cancer cell survival by inducing autophagy
,Niture, S;Ramalinga, M;Kedir, H;Patacsil, D;Niture, SS;Li, J;Mani, H;Suy, S;Collins, S;Kumar, D;,
Oncotarget
,PubMed ID 29928491
[TNFAIP8]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC202729L1 | Lenti ORF clone of Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
RC202729L2 | Lenti ORF clone of Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC202729L3 | Lenti ORF clone of Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC202729L4 | Lenti ORF clone of Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RG202729 | TNFAIP8 (tGFP-tagged) - Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1 |
CNY 4,000.00 |
|
SC312385 | TNFAIP8 (untagged)-Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1 |
CNY 3,990.00 |
|
SC317294 | TNFAIP8 (untagged)-Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1 |
CNY 3,990.00 |
|
SC320774 | TNFAIP8 (untagged)-Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1 |
CNY 2,400.00 |
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