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Olr1 (NM_138648) Mouse Tagged ORF Clone
CAT＃: MR226641
- TrueORF®
Olr1 (Myc-DDK-tagged) - Mouse oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1)
ORF Plasmid: tGFP
"NM_138648" in other vectors (4)
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CNY 2,850.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | LOX-1; Scare1; SR-EI |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR226641 representing NM_138648
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTTTTGATGACAAGATGAAGCCTGCGAATGACGAGCCTGATCAGAAGTCATGTGGCAAGAAGCCTA AAGGTCTGCATTTGCTTTCTTCCCCATGGTGGTTCCCTGCTGCTATGACTCTGGTCATCCTCTGCCTGGT GTTGTCAGTGACCCTTATTGTACAGTGGACACAATTACGCCAGGTATCTGACCTCTTAAAACAATACCAA GCGAACCTTACTCAGCAGGATCGTATCCTGGAAGGGCAGATGTTAGCCCAGCAGAAGGCAGAAAACACTT CACAGGAATCAAAGAAGGAACTGAAAGGAAAGATAGACACCCTCACCCAGAAGCTGAACGAGAAATCCAA AGAGCAGGAGGAGCTTCTACAGAAGAATCAGAACCTCCAAGAAGCCCTGCAAAGAGCTGCAAACTCTTCA GAGGAGTCCCAGAGAGAACTCAAGGGAAAGATAGACACCATCACCCGGAAGCTGGACGAGAAATCCAAAG AGCAGGAGGAGCTTCTGCAGATGATTCAGAACCTCCAAGAAGCCCTGCAGAGAGCTGCAAACTCTTCAGA GGAGTCCCAGAGAGAACTCAAGGGAAAGATAGACACCCTCACCTTGAAGCTGAACGAGAAATCCAAAGAG CAGGAGGAGCTTCTACAGAAGAATCAGAACCTCCAAGAAGCCCTGCAAAGAGCTGCAAACTTTTCAGGTC CTTGTCCACAAGACTGGCTCTGGCATAAAGAAAACTGTTACCTCTTCCATGGGCCCTTTAGCTGGGAAAA AAACCGGCAGACCTGCCAATCTTTGGGTGGCCAGTTACTACAAATTAATGGTGCAGATGATCTGACATTC ATCTTACAAGCAATTTCCCATACCACCTCCCCGTTCTGGATTGGATTGCATCGGAAGAAGCCTGGCCAAC CATGGCTATGGGAGAATGGAACTCCTTTGAATTTTCAATTCTTTAAGACCAGGGGCGTTTCTTTACAGCT ATATTCATCAGGCAACTGTGCATACCTTCAAGACGGAGCTGTGTTCGCTGAAAACTGCATTCTAATTGCA TTCAGCATATGTCAGAAGAAGACAAATCATTTGCAAATT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR226641 representing NM_138648
Red=Cloning site Green=Tags(s) MTFDDKMKPANDEPDQKSCGKKPKGLHLLSSPWWFPAAMTLVILCLVLSVTLIVQWTQLRQVSDLLKQYQ ANLTQQDRILEGQMLAQQKAENTSQESKKELKGKIDTLTQKLNEKSKEQEELLQKNQNLQEALQRAANSS EESQRELKGKIDTITRKLDEKSKEQEELLQMIQNLQEALQRAANSSEESQRELKGKIDTLTLKLNEKSKE QEELLQKNQNLQEALQRAANFSGPCPQDWLWHKENCYLFHGPFSWEKNRQTCQSLGGQLLQINGADDLTF ILQAISHTTSPFWIGLHRKKPGQPWLWENGTPLNFQFFKTRGVSLQLYSSGNCAYLQDGAVFAENCILIA FSICQKKTNHLQI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_138648 |
| ORF Size | 1089 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_138648.2, NP_619589.2 |
| RefSeq Size | 3581 bp |
| RefSeq ORF | 1092 bp |
| Locus ID | 108078 |
| UniProt ID | Q9EQ09 |
| MW | 42.1 kDa |
| Gene Summary | Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC212167 | Olr1 (untagged) - Mouse oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1), (10ug) |
CNY 3,656.00 |
|
| MG226641 | Olr1 (tGFP-tagged) - Mouse oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1), (10ug) |
CNY 3,140.00 |
|
| MR226641L3 | Lenti ORF clone of Olr1 (Myc-DDK-tagged) - Mouse oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1) |
CNY 4,750.00 |
|
| MR226641L4 | Lenti ORF clone of Olr1 (mGFP-tagged) - Mouse oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1) |
CNY 4,750.00 |
