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Nrxn1 (NM_177284) Mouse Tagged ORF Clone
CAT＃: MR226544
- TrueORF®
Nrxn1 (Myc-DDK-tagged) - Mouse neurexin I (Nrxn1), transcript variant 2
ORF Plasmid: tGFP
"NM_177284" in other vectors (4)
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CNY 14,920.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 1700062G21Rik; 9330127H16Rik; A230068P09Rik; mKIAA0578 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR226544 representing NM_177284
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGACGGCGCTGGTCCAGCGCGGGGGCTGCTGTCTCCTCTGCCTGTCGCTGCTGCTGCTGGGCTGCT GGGCAGAGCTGGGCAGCGGGCTGGAGTTCCCGGGCGCCGAGGGCCAGTGGACGCGCTTCCCCAAGTGGAA CGCGTGCTGCGAGAGCGAGATGAGCTTCCAGCTGAAGACGCGCAGTGCCCGCGGCCTCGTGCTCTACTTC GACGACGAGGGCTTCTGCGACTTCCTCGAGCTCATCCTGACGCGCGGCGGCCGCCTGCAGCTCAGCTTCT CCATCTTCTGCGCCGAGCCCGCCACGCTGTTGGCCGACACGCCGGTCAACGACGGCGCCTGGCACAGCGT GCGCATCCGCCGCCAGTTCCGCAACACCACGCTCTACATCGACCGCGCCGAGGCCAAGTGGGTGGAGGTC AAGTCCAAGCGCAGGGACATGACGGTGTTCAGCGGGCTCTTCGTGGGCGGCCTGCCACCCGAACTGCGCG CCGCGGCCCTCAAGCTCACGCTGGCCTCGGTGCGCGAGCGCGAGCCCTTCAAGGGCTGGATCCGTGACGT CCGGGTCAACTCGTCACAGGCCCTGCCGGTGGACGGCGGCGAGGTCAAGCTGGACGACGAGCCTCCCAAC AGCGGTGGCGGGAGCCCATGCGAGGCGGGCGAAGAAGGCGAGGGCGGCGTGTGCCTCAACGGGGGCGTGT GCTCCGTGGTCGACGACCAGGCCGTATGCGACTGCTCGAGGACCGGCTTCCGTGGCAAGGACTGCAGCCA AGAAGACAACAATGTGGAAGGTCTGGCACACCTGATGATGGGCGACCAAGGAAAAGAAGAGTATATTGCC ACGTTCAAGGGATCTGAATACTTCTGCTACGACTTATCTCAAAACCCCATTCAAAGCAGCAGTGATGAAA TAACTCTGTCCTTTAAAACTCTTCAAAGGAACGGACTGATGCTTCACACAGGGAAATCAGCTGATTATGT CAATCTTGCATTGAAAAATGGAGCTGTCTCTCTGGTCATTAATTTGGGATCAGGGGCCTTTGAAGCACTA GTGGAGCCTGTGAATGGAAAGTTTAATGATAATGCCTGGCATGATGTGAAAGTCACCAGGAATCTGCGTC AGGTGACAATATCAGTGGATGGAATTCTTACCACAACGGGCTACACGCAAGAAGATTACACCATGCTGGG GTCTGATGACTTTTTCTATGTTGGAGGCAGCCCCAGCACAGCCGACCTTCCAGGGTCACCAGTCAGTAAC AACTTTATGGGCTGTCTCAAAGAGGTTGTATATAAAAATAATGATGTAAGGCTGGAATTATCGCGACTTG CCAAGCAAGGAGATCCTAAGATGAAGATTCACGGTGTGGTGGCTTTTAAGTGTGAAAATGTGGCAACCTT AGACCCAATAACTTTTGAGACCCCGGAATCTTTCATTTCTTTGCCTAAGTGGAATGCAAAGAAAACAGGC TCAATATCATTTGATTTCCGTACAACGGAGCCAAATGGCCTCATCCTGTTTAGCCATGGCAAGCCAAGAC ATCAGAAGGATGCCAAGCACCCACAGATGATTAAGGTTGACTTTTTTGCTATTGAGATGCTGGATGGCCA CTTGTACCTCCTCTTAGACATGGGATCAGGTACTATAAAAATCAAAGCCCTGCAGAAGAAAGTCAATGAT GGAGAATGGTATCACGTGGATTTCCAACGGGATGGACGGTCAGGTACCATTTCTGTCAACACACTACGCA CTCCCTACACAGCTCCCGGTGAGAGTGAGATCCTGGACCTAGATGATGAGTTGTACCTGGGTGGCTTGCC AGAAAATAAGGCTGGCCTAGTCTTCCCTACCGAGGTGTGGACTGCTCTGCTCAACTACGGCTACGTGGGC TGCATCCGGGACCTATTTATTGATGGCCAGAGCAAAGACATCCGGCAGATGGCGGAAATTCAGAGCACTG CTGGAGTGAAGCCATCCTGCTCAAAAGAGACAGCAAAACCGTGCCTTAGCAATCCTTGCAAAAACAATGG CATGTGCAGAGATGGCTGGAACAGATACGTCTGCGATTGCTCCGGAACAGGCTATCTCGGCAGGTCCTGT GAGAGAGAGGCAACGGTTTTGAGCTACGACGGGAGCATGTTCATGAAAATCCAGCTTCCGGTGGTGATGC ACACTGAGGCTGAGGACGTGTCCTTGCGGTTCCGATCCCAGCGTGCATATGGTATCCTGATGGCGACCAC TTCTAGAGACTCTGCAGACACCCTTCGATTGGAGCTAGATGCAGGACGTGTGAAACTCACGGTCAATCTA GATTGTATCAGGATTAACTGTAATTCCAGCAAAGGTCCTGAGACCCTTTTTGCTGGCTATAACCTCAATG ATAATGAATGGCACACAGTGCGTGTGGTTCGGCGAGGAAAAAGTTTAAAGCTAACCGTGGATGATCAACA AGCCATGACAGGCCAAATGGCAGGTGATCATACAAGGCTGGAGTTTCATAACATAGAGACAGGCATCATC ACCGAACGACGCTACCTTTCTTCTGTCCCCTCCAATTTCATTGGGCACCTGCAAAGCCTGACATTTAATG GAATGGCATACATAGACTTGTGCAAAAATGGTGATATAGATTACTGTGAACTCAATGCCAGGTTTGGATT CAGGAACATCATCGCAGATCCTGTCACCTTCAAGACCAAATCGAGCTATGTTGCCTTAGCTACATTGCAA GCCTACACCTCTATGCATCTATTTTTCCAATTCAAGACAACATCTCTAGATGGACTAATTCTGTATAACA GTGGGGATGGAAATGACTTTATTGTGGTTGAATTAGTTAAAGGGTACTTACATTATGTGTTTGACTTGGG AAACGGTGCTAACCTCATCAAAGGGAGCTCAAACAAACCACTCAACGACAATCAGTGGCACAATGTGATG ATTTCACGGGACACCAGCAATCTCCACACAGTAAAGATCGACACAAAAATCACAACACAAATCACTGCGG GAGCCAGAAATCTAGACCTCAAGAGTGACTTGTATATTGGAGGAGTGGCTAAAGAAACATATAAATCCCT GCCAAAACTGGTCCATGCCAAAGAAGGCTTTCAAGGTTGCCTGGCATCTGTGGACTTGAATGGCAGACTT CCAGATCTCATCTCGGATGCTCTCTTCTGCAATGGGCAAATTGAGAGAGGATGCGAAGGGCCCAGCACAA CCTGCCAAGAGGATTCATGTTCAAATCAAGGCGTTTGCTTGCAGCAATGGGATGGCTTCAGCTGTGACTG TAGCATGACTTCCTTCAGTGGCCCACTCTGCAATGACCCTGGGACAACATATATCTTTAGCAAAGGTGGT GGACAGATTACATATAAGTGGCCTCCCAATGACCGCCCCAGTACACGAGCAGACAGGCTGGCCATCGGAT TTAGCACTGTCCAGAAGGAAGCCGTGTTGGTGCGTGTGGACAGTTCCTCAGGACTGGGTGACTACCTGGA GCTGCACATACACCAAGGAAAAATTGGAGTTAAGTTTAATGTTGGGACAGATGACATCGCCATCGAAGAG TCTAATGCAATCATTAATGATGGGAAATACCATGTAGTACGTTTCACAAGGAGTGGTGGCAATGCCACGT TACAGGTGGACAGCTGGCCAGTTATCGAACGCTACCCTGCAGGAAACAATGATAACGAGCGCCTGGCGAT TGCTAGACAGCGAATTCCATATCGACTTGGTCGAGTAGTTGATGAATGGCTACTCGACAAAGGGCGTCAG CTCACAATCTTCAATAGCCAAGCAACCATAATAATTGGCGGGAAAGAGCAGGGCCAGCCCTTCCAGGGCC AGCTCTCTGGTCTTTACTACAATGGCTTGAAAGTTCTGAATATGGCAGCAGAGAACGATGCCAACATCGC CATAGTGGGGAATGTGAGGCTGGTCGGTGAAGTGCCTTCCTCTATGACAACTGAGTCGACAGCCACTGCC ATGCAGTCTGAGATGTCCACCTCAATCATGGAGACCACCACAACCCTGGCTACCAGCACAGCTAGAAGAG GCAAGCCCCCCACAAAGGAACCCATCAGCCAGACCACAGATGACATCCTTGTGGCCTCGGCAGAGTGTCC CAGTGACGATGAGGACATTGACCCCTGTGAGCCGAGCTCAGGTGGGTTAGCCAACCCCACCAGAGTAGGT GGCCGTGAACCATACCCAGGCTCTGCAGAGGTGATTCGGGAGTCCAGCAGTACCACTGGCATGGTGGTGG GGATTGTCGCAGCAGCCGCTCTGTGCATCCTCATCCTCCTCTATGCCATGTACAAGTACAGGAACCGGGA TGAAGGGTCGTACCACGTGGATGAGAGTCGAAACTACATCAGTAACTCAGCACAGTCCAATGGGGCTGTG GTCAAGGAGAAGCAACCCAGCAGTGCTAAAAGCGCCAACAAAAACAAGAAAAACAAGGATAAGGAGTATT ACGTC AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA >MR226544 representing NM_177284
Red=Cloning site Green=Tags(s) MGTALVQRGGCCLLCLSLLLLGCWAELGSGLEFPGAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYF DDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRNTTLYIDRAEAKWVEV KSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQALPVDGGEVKLDDEPPN SGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQGKEEYIA TFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEAL VEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSN NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTG SISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVND GEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVG CIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSC EREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNL DCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGII TERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKSSYVALATLQ AYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVM ISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRL PDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGG GQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEE SNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQ LTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATA MQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRVG GREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAV VKEKQPSSAKSANKNKKNKDKEYYV SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_177284 |
| ORF Size | 4485 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_177284.2, NP_796258.2 |
| RefSeq Size | 9004 bp |
| RefSeq ORF | 4488 bp |
| Locus ID | 18189 |
| UniProt ID | Q9CS84 |
| MW | 164.6 kDa |
| Gene Summary | This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are synaptic transmembrane receptors that bind endogenous ligands that include neuroligins, dystroglycan, and neurexophilins. Neurexin complexes are required for efficient neurotransmission and are involved in synaptogenesis. In vertebrates, alternate promoter usage results in multiple isoform classes, of which the alpha and beta classes are the best characterized. In humans, allelic variants in this gene are associated with Pitt-Hopkins-like syndrome-2, while deletions have been associated with autism and schizophrenia. Mouse knockouts display decreased spontaneous and evoked vesicle release resulting in impaired synaptic transmission. In addition, knockout mice show altered social approach, reduced social investigation, reduced locomotor activity, and in males, increased aggression. Alternative splicing and promoter usage result in multiple transcript variants. [provided by RefSeq, Nov 2016] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC224600 | Nrxn1 (untagged) - Mouse neurexin I (Nrxn1), transcript variant 2, (10ug) |
CNY 19,190.00 |
|
| MG226544 | Nrxn1 (tGFP-tagged) - Mouse neurexin I (Nrxn1) transcript variant 2, (10ug) |
CNY 16,440.00 |
|
| MR226544L3 | Lenti ORF clone of Nrxn1 (Myc-DDK-tagged) - Mouse neurexin I (Nrxn1), transcript variant 2 |
CNY 16,820.00 |
|
| MR226544L4 | Lenti ORF clone of Nrxn1 (mGFP-tagged) - Mouse neurexin I (Nrxn1), transcript variant 2 |
CNY 16,820.00 |
