Cpeb4 (NM_026252) Mouse Tagged ORF Clone
CAT#: MR224198
- TrueORF®
Cpeb4 (Myc-DDK-tagged) - Mouse cytoplasmic polyadenylation element binding protein 4 (Cpeb4)
ORF Plasmid: tGFP
"NM_026252" in other vectors (4)
Need custom modification / cloning service?
Get a free quote
CNY 5,344.00
CNY 6,460.00
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | Cpe-bp4; Cpeb-4; mCPEB-4 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR224198 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGGATTACGGGTTTGGAGTGCTAGTGCAAAGCAATACTGGGAATAAATCTGCTTTTCCAGTCCGAT TCCATCCACATCTGCAGCCTCCACACCATCACCAAAATGCCACCCCCAACCCTGCTGCTTTTATAAATAA TAACACAGCTGCCAATGGCAGCAGTGCTGGGTCAGCCTGGCTCTTTCCTGCCCCGGCTACTCATAACATT CAGGATGAGATCTTGGGGTCAGAAAAAGCAAAAAGTCAACAGCAAGAACAACAAGACCCTTTAGAAAAGC AACAGCTCTCCCCGAGTCCAGGTCAGGAAGCTGGAATACTGCCTGAAACTGAAAAGGCAAAAGCTGAAGA AAATCCAGGGGACAGTTCTTCAGAAAACAGCAACGGAAAAGAAAAACTACGCATTGAATCACCAGTGTTG ACAGGGTTTGATTACCAAGAAGCCACCGGTCTCGGGACTTCCACCCAACCCTTGACATCCAGTGCATCGT CCCTTACTGGTTTCAGTAACTGGTCAGCAGCGATAGCACCTTCTTCCTCCACTATAATCAATGAAGATGC AAGTTTCTTTCACCAGGGAGGGGTCCCTGGCGCTTCAGCTAATAATGGTGCTCTCTTGTTTCAAAATTTT CCCCATCATGTCAGCCCTGGCTTTGGTGGTAGCTTCTCCCCTCAGATCGGGCCTCTCTCCCAGCACCATC CTCATCACCCCCATTTCCAGCACCATCACAGCCAGCATCAGCAGCAGAGGAGGTCTCCTGCCAGTCCCCA CCCCCCACCTTTCACACATAGAAGTGCTGCTTTTAACCAGCTGCCTCATTTGGCGAATAATCTTAACAAA CCTCCTTCTCCATGGAGCAGCTACCAAAGTCCTTCTCCAACCCCCTCTTCTTCCTGGAGCCCAGGAGGTG GCGGCTACGGTGGCTGGGGAGCATCTCAAGGCCGGGATCACCGCAGAGGGCTGAACGGTGGAATAACACC CCTGAACTCAATCTCACCTTTGAAGAAAAATTTCGCAAGCAATCATATTCAGCTCCAGAAGTATGCTCGC CCTAGCTCAGCCTTTGCTCCAAAATCCTGGATGGAAGATAGCTTGAACAGGGCTGACAACATTTTTCCTT TTCCGGAACGCCCCAGGACGTTTGACATGCACTCACTGGAGAGCTCACTCATTGACATAATGAGAGCTGA AAATGATTCCATTAAAGGTCGTCTAAACTATTCATACCCAGGATCCGATAGTTCTCTGCTTATTAATGCA AGGACTTATGGGCGAAGGAGAGGTCAGTCTTCATTGTTTCCGATGGAAGATGGATTCCTGGATGATGGCC GTGGGGATCAACCTCTTCATAGTGGTCTGGGGTCACCTCACTGCTTCACTCACCAGAATGGGGAGAGAGT GGAACGATACTCTCGCAAAGTGTTTGTGGGTGGATTGCCTCCTGATATTGATGAAGATGAGATCACAGCT AGTTTCCGTCGCTTTGGCCCTTTGATTGTGGATTGGCCTCATAAGGCAGAGAGCAAATCTTATTTTCCAC CAAAAGGCTATGCATTCCTGCTGTTTCAAGATGAAAGTTCTGTTCAGGCTCTCATTGATGCATGTATTGA AGAAGATGGAAAACTTTACCTGTGTGTATCAAGTCCAACCATCAAGGATAAACCAGTGCAGATCCGGCCC TGGAATCTCAGTGACAGTGACTTTGTGATGGATGGCTCACAGCCACTTGACCCACGGAAAACAATATTTG TTGGTGGTGTTCCTCGACCATTACGAGCTGTGGAGCTTGCAATGATAATGGATCGGCTGTATGGAGGCGT CTGCTATGCTGGAATCGATACTGACCCAGAGCTCAAATACCCAAAAGGAGCTGGAAGAGTCGCGTTTTCT AATCAACAGAGTTACATAGCTGCTATCAGTGCCCGCTTTGTTCAGCTGCAGCATGGAGAGATAGATAAAC GGGTGGAGGTTAAGCCATATGTCTTGGATGACCAGCTGTGTGATGAATGTCAAGGGGCCCGTTGTGGGGG GAAATTTGCTCCATTTTTCTGTGCTAATGTTACCTGTCTGCAGTATTACTGTGAATATTGCTGGGCTGCT ATTCACTCTCGTGCTGGCAGAGAATTCCACAAGCCCCTGGTGAAGGAAGGTGGTGACCGCCCTCGGCATA TTTCATTCCGCTGGAAC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR224198 protein sequence
Red=Cloning site Green=Tags(s) MGDYGFGVLVQSNTGNKSAFPVRFHPHLQPPHHHQNATPNPAAFINNNTAANGSSAGSAWLFPAPATHNI QDEILGSEKAKSQQQEQQDPLEKQQLSPSPGQEAGILPETEKAKAEENPGDSSSENSNGKEKLRIESPVL TGFDYQEATGLGTSTQPLTSSASSLTGFSNWSAAIAPSSSTIINEDASFFHQGGVPGASANNGALLFQNF PHHVSPGFGGSFSPQIGPLSQHHPHHPHFQHHHSQHQQQRRSPASPHPPPFTHRSAAFNQLPHLANNLNK PPSPWSSYQSPSPTPSSSWSPGGGGYGGWGASQGRDHRRGLNGGITPLNSISPLKKNFASNHIQLQKYAR PSSAFAPKSWMEDSLNRADNIFPFPERPRTFDMHSLESSLIDIMRAENDSIKGRLNYSYPGSDSSLLINA RTYGRRRGQSSLFPMEDGFLDDGRGDQPLHSGLGSPHCFTHQNGERVERYSRKVFVGGLPPDIDEDEITA SFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRP WNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFS NQQSYIAAISARFVQLQHGEIDKRVEVKPYVLDDQLCDECQGARCGGKFAPFFCANVTCLQYYCEYCWAA IHSRAGREFHKPLVKEGGDRPRHISFRWN TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
![]() |
ACCN | NM_026252 |
ORF Size | 2190 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_026252.2, NM_026252.3, NM_026252.4, NP_080528.2 |
RefSeq Size | 7655 bp |
RefSeq ORF | 2190 bp |
Locus ID | 67579 |
UniProt ID | Q7TN98 |
MW | 80.1 kDa |
Gene Summary | Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3' UTR (PubMed:17024188). RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (By similarity). Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE-regulated mRNAs in conditions in which global protein synthesis is inhibited (PubMed:28092655). Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (By similarity). Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752). Stimulates proliferation of melanocytes (By similarity). In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory (PubMed:24386439).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC221171 | Cpeb4 (untagged) - Mouse cytoplasmic polyadenylation element binding protein 4 (Cpeb4), (10ug) |
CNY 9,500.00 |
|
MG224198 | Cpeb4 (tGFP-tagged) - Mouse cytoplasmic polyadenylation element binding protein 4 (Cpeb4), (10ug) |
CNY 7,130.00 |
|
MR224198L3 | Lenti ORF clone of Cpeb4 (Myc-DDK-tagged) - Mouse cytoplasmic polyadenylation element binding protein 4 (Cpeb4) |
CNY 8,360.00 |
|
MR224198L4 | Lenti ORF clone of Cpeb4 (mGFP-tagged) - Mouse cytoplasmic polyadenylation element binding protein 4 (Cpeb4) |
CNY 8,360.00 |