Dpp4 (NM_010074) Mouse Tagged ORF Clone
CAT#: MR222697
- TrueORF®
Dpp4 (Myc-DDK-tagged) - Mouse dipeptidylpeptidase 4 (Dpp4), transcript variant 1
ORF Plasmid: tGFP
"NM_010074" in other vectors (3)
Need custom modification / cloning service?
Get a free quote
CNY 5,568.00
CNY 5,800.00
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | Cd26; Dpp-4; THAM |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR222697 representing NM_010074
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGACACCGTGGAAGGTTCTTCTGGGACTGCTTGGTGTCGCTGCGCTTGTCACCATCATCACCGTGC CAATAGTTCTGCTGAGCAAAGATGAAGCGGCAGCTGACAGCCGCAGAACGTATTCACTAGCTGACTATTT AAAGAGTACCTTTCGGGTCAAGTCCTACTCTTTGTGGTGGGTTTCAGACTTTGAATACCTCTACAAACAA GAGAACAATATCTTGCTGCTCAATGCTGAACATGGAAACAGCTCCATTTTCTTGGAGAACAGTACCTTTG AAAGCTTTGGATATCATTCAGTGTCACCTGACCGACTGTTTGTTCTCTTGGAATACAACTACGTGAAGCA ATGGAGACATTCCTACACAGCTTCATACAACATTTATGATGTGAATAAAAGACAGCTGATCACAGAAGAG AAGATTCCAAATAATACACAGTGGATCACATGGTCACCAGAAGGTCATAAGTTGGCATATGTCTGGAAGA ATGATATTTACGTTAAAGTTGAACCACACTTACCTAGTCATAGGATCACATCGACAGGAGAAGAAAATGT AATATATAATGGAATAACTGACTGGGTTTATGAAGAGGAAGTCTTCGGTGCCTACTCTGCACTGTGGTGG TCTCCAAACAACACGTTTCTAGCTTATGCCCAGTTTAACGACACAGGAGTGCCGCTCATTGAATACTCCT TCTATTCTGATGAGTCACTGCAGTACCCCAAGACAGTGTGGATTCCATACCCAAAGGCAGGAGCTGTGAA TCCAACTGTAAAGTTCTTTATTGTAAATATAGACTCTCTCAGCTCATCCTCTAGTGCGGCTCCCATCCAA ATCCCTGCTCCTGCATCTGTGGCAAGAGGGGATCACTATTTATGTGATGTGGTGTGGGCTACAGAAGAAA GAATTTCACTACAGTGGCTCAGGAGGATTCAGAACTATTCCGTGATGGCTATCTGTGACTATGATAAGAT CAACCTAACGTGGAACTGTCCATCCGAGCAGCAGCATGTTGAAATGAGTACCACAGGCTGGGTCGGAAGA TTTAGGCCCGCAGAACCTCACTTCACCTCTGATGGAAGCAGCTTCTATAAGATCATCAGCGACAAAGATG GCTACAAACACATCTGCCACTTCCCGAAAGATAAGAAAGACTGTACATTTATTACAAAAGGAGCCTGGGA AGTCATTAGTATCGAAGCTCTGACCAGCGATTATCTATACTACATTAGTAACCAATATAAAGAAATGCCA GGAGGAAGAAATCTCTATAAAATTCAACTTACTGACCACACAAATGTGAAGTGCCTTAGTTGTGACCTGA ATCCAGAAAGATGTCAGTATTATGCGGTATCATTTAGTAAAGAGGCAAAGTACTATCAGCTGGGATGTTG GGGCCCCGGTCTGCCCCTCTACACTCTACATCGTAGCACGGATCATAAAGAGCTGCGAGTCCTGGAAGAC AATTCTGCTTTGGATAGAATGCTGCAGGATGTCCAGATGCCTTCAAAAAAATTGGACTTCATTGTTTTGA ATGAAACAAGATTTTGGTATCAAATGATCTTGCCCCCTCATTTTGATAAATCCAAGAAATATCCTCTACT ATTAGATGTATATGCAGGTCCCTGTAGTCAAAAAGCAGATGCTTCCTTCAGACTGAACTGGGCCACTTAC CTTGCAAGTACAGAAAACATCATAGTAGCTAGCTTTGACGGCAGAGGAAGTGGTTACCAAGGAGATAAGA TCATGCATGCAATCAACAGAAGATTGGGAACACTGGAAGTTGAAGATCAAATTGAAGCAGCCAGGCAATT TGTAAAAATGGGATTTGTGGATAGCAAGCGAGTTGCAATTTGGGGCTGGTCATATGGAGGGTATGTAACC TCAATGGTCCTGGGATCGGGAAGTGGCGTGTTCAAGTGCGGAATAGCTGTGGCACCTGTGTCACGGTGGG AGTACTATGACTCAGTGTACACAGAGCGTTACATGGGTCTCCCAATTCCAGAAGACAACCTTGACCATTA CAGGAACTCAACAGTCATGAGCAGAGCTGAACATTTTAAACAAGTTGAGTACCTCCTTATTCATGGAACG GCAGATGATAATGTTCACTTTCAGCAGTCAGCTCAGATCTCCAAAGCCCTGGTGGATGCTGGTGTGGATT TCCAAGCAATGTGGTACACGGATGAAGACCACGGGATCGCTAGCAGCACAGCTCACCAGCACATCTATTC CCACATGAGCCATTTCCTCCAGCAGTGCTTCTCCTTACAC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR222697 representing NM_010074
Red=Cloning site Green=Tags(s) MKTPWKVLLGLLGVAALVTIITVPIVLLSKDEAAADSRRTYSLADYLKSTFRVKSYSLWWVSDFEYLYKQ ENNILLLNAEHGNSSIFLENSTFESFGYHSVSPDRLFVLLEYNYVKQWRHSYTASYNIYDVNKRQLITEE KIPNNTQWITWSPEGHKLAYVWKNDIYVKVEPHLPSHRITSTGEENVIYNGITDWVYEEEVFGAYSALWW SPNNTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNIDSLSSSSSAAPIQ IPAPASVARGDHYLCDVVWATEERISLQWLRRIQNYSVMAICDYDKINLTWNCPSEQQHVEMSTTGWVGR FRPAEPHFTSDGSSFYKIISDKDGYKHICHFPKDKKDCTFITKGAWEVISIEALTSDYLYYISNQYKEMP GGRNLYKIQLTDHTNVKCLSCDLNPERCQYYAVSFSKEAKYYQLGCWGPGLPLYTLHRSTDHKELRVLED NSALDRMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADASFRLNWATY LASTENIIVASFDGRGSGYQGDKIMHAINRRLGTLEVEDQIEAARQFVKMGFVDSKRVAIWGWSYGGYVT SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPIPEDNLDHYRNSTVMSRAEHFKQVEYLLIHGT ADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSLH TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
![]() |
ACCN | NM_010074 |
ORF Size | 2280 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_010074.3, NP_034204.1 |
RefSeq Size | 5268 bp |
RefSeq ORF | 2283 bp |
Locus ID | 13482 |
UniProt ID | P28843 |
MW | 87.9 kDa |
Gene Summary | Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG222697 | Dpp4 (tGFP-tagged) - Mouse dipeptidylpeptidase 4 (Dpp4) transcript variant 1, (10ug) |
CNY 6,370.00 |
|
MR222697L3 | Lenti ORF clone of Dpp4 (Myc-DDK-tagged) - Mouse dipeptidylpeptidase 4 (Dpp4), transcript variant 1 |
CNY 7,968.00 |
|
MR222697L4 | Lenti ORF clone of Dpp4 (mGFP-tagged) - Mouse dipeptidylpeptidase 4 (Dpp4), transcript variant 1 |
CNY 7,968.00 |