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Xpo4 (NM_020506) Mouse Tagged ORF Clone
CAT＃: MR220257
- TrueORF®
Xpo4 (Myc-DDK-tagged) - Mouse exportin 4 (Xpo4)
ORF Plasmid: tGFP
"NM_020506" in other vectors (4)
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CNY 8,016.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | B430309A01Rik; mKIAA1721 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR220257 representing NM_020506
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGATGGCGGCGGCGCTGGGGCCCCCAGAAGTGATCGCTCAGCTGGAGAACGCGGCCAAAGTTCTGATGG CACCACCTTCCATGGTCAGTAATGAGCAGCGCCAGCATGCAGAGCACATATTCCTATCATTTAGGAAGTC CAAATCACCATTTGCAGTTTGCAGGCATATTTTGGAAACCAGTAAAGTGGACTATGTCCTTTTTCAAGCT GCCACAGCTATAATGGAAGCGGTTGTCCGAGAGTGGGTTCTCTTGGAAAAGGGCAGCATCGAGTCACTGA GAACATTCCTCCTCACCTATGTCTTGCAAAGGCCTAACCTCCAAAAGTATGTTCGGGAACAGATTCTATT AGCAGTAGCAGTGATTGTAAAAAGAGGATCATTAGATAAGTCAATTGACTGCAAAAGCATATTTCATGAA GTCAGCCAGTTGATAAGTAGTGGCAATCCCACTGTGCAAACTCTGGCCTGTTCTATTCTAACTGCTCTAT TGAGTGAATTTTCAAGTTCAAGTAAAACTAGCAACATTGGGCTGAGTATGGAATTCCACGGTAACTGCAA GCGAGTCTTTCAGGAAGAAGACCTTCGGCAGATCTTCATGTTAACAGTTGGAGTTCTGCAGGAGTTCAGC AGACGGGAGAACCTCAGTGCTCAGATGTCCTCAGTGTTTCAGCGGTACCTCGCCCTCGCCAACCAAGTCC TGAGCTGGAATTTTCTCCCTCCAAATTTGGGCAGACATTATATAGCTATGTTTGAATCCTCACAAAATGT GCTGTTGAAGCCAACAGAGTCCTGGCGGGAGGCTCTTCTGGACAGCAGAGTTATGGAGCTCTTCTTCACT GTACATCGAAAAATCAGAGAAGATTCAGATATGGCACAGGATTCCCTGCAGTGCCTTGCCCAGTTAGCGT CTCTCCACGGACCCATCTTCCCCGACGAAGGATCCCAGGTTGATTATCTAGCACACTTCATTGAGGGCTT GCTCAACACTATTAATGGAATTGAAATAGAAGATTCTGAAGCCGTAGGGATCTCCAGCATTATCAGCAAT CTGATAACTGTGTTCCCTCGGAATGTTTTAACTGCCATCCCCAGTGAGCTCTTCTCCTCCTTTGTGAACT GCCTCACACACCTCACTTGTTCTTTTGGGCGAAGTGCTGCGTTGGAAGAAGTGCTTGATAAGGATGACAT GGTATACATGGAAGCATATGATAAATTGCTGGAGTCCTGGCTAACTTTGGTCCGAGATGACAAGCATTTC CATAAAGGCTTTTTCACACAGCATGCAGTTCAGGTGTTCAATTCCTATATTCAATGTCACCTTGCTGCTC CAGATGGCACAAGAAATTTGACAGCCAATGGTGTGGCCTCGCGTGAGGAAGAAGAAATAAGTGAGCTCCA AGAGGATGATCGTGATCAGTTTTCCGACCAACTAGCCAGCGTAGGAATGCTGGGACGGATTGCTGCCGAA CACTGTATGCCTCTTCTGACAAGTTTATTAGAAGAAAGGGTAACAAGACTCCATGGCCAGTTACAACGGC ATCAGCAACAATTCCTTGCTTCACCCGGATCAAGCACCATTGACAACAAAATGCTTGACGATCTTTACGA GGATATTCACTGGCTTATTCTAGTTACAGGCTACCTCTTAGCTGATGATACTCAGGGAGAGACTCCGCTA ATACCTCCAGAAATAATGGAATATTCCATTAAGCATTCATCTGAAGTTGACATTAATACAACACTTCAAA TTTTGGGATCTCCAGGAGAAAAGGCTTCTTCCATCCCAGGGTACAGCAGAACAGATTCTGTGATTAGGCT GTTGTCTGCTGTGCTAAGAGTCTCAGAAGTTGAATCTCGAGCAATAAGAGCAGATCTCACTCATCTACTA AGCCCTCAGATGGGCAAAGATATTGTTTGGTTTCTAAAACGCTGGGCCAAGACTTACCTCCTGGTAGATG AAAAACTGTATGATCAGATAAGTTTGCCATTGAGCACAGCATTTGGAGCGGATACAGAGGGTTCCCAGTG GATTATCGGCTACCTCTTACAAAAGGTCATCAGCAATCTGTCGGTATGGAGCAGTGAACAGGACCTCGCG AATGACACTGTTCAGCTCCTTGTCACTTTGGTAGAAAGAAGAGAAAGGGCAAACTTAGTAATTCAGTGTG AAAACTGGTGGAACCTAGCAAAGCAGTTTGCAAGCCGAAGCCCACCTCTTAACTTCCTGTCCAGTCCAGT GCAGAGGACACTGATGAAGGCTCTGGTCTTAGGAGGCTTTGCACATATGGACACAGAAACCAAGCAGCAG TATTGGACTGAGGTTCTGCAGCCTCTTCAGCAGAGGTTCCTGAGAGTGATCAACCAAGAGAACTTTCAGC AGATGTGTCAGCAGGAGGAAGTCAAGCAGGAGATCACTGCCACATTGGAGGCCCTGTGTGGCATTGCTGA GGCCACCCAGATCGACAATGTAGCCATCCTTTTTAATTTTTTAATGGACTTCCTTAACAATTGCATTGGT TTAATGGAAGTTTACAAAAATACTCCAGAAACTGTCAATCTCATTATAGAAGTTTTTGTTGAAGTTGCAC ATAAACAAATATGCTATCTTGGAGAGTCCAAAGCTATGCATTTATACGAAGCCTGCCTTACTTTGTTACA AGTGTATTCTAAGAATAACTTAGGGCGGCAAAGGATAGACGTCACGGCGGAGGAAGAGCAGTACCAAGAC CTGCTTCTCATCATGGAGCTTCTCACTAACCTTCTCTCAAAGGAGTTCATCGACTTTAGTGACACAGATG AAGTGTTTAGAGGACATGAGCCAGGACAAGCAGCAGGCAGATCTGTATCGGCAGCTGATGTCGTTTTATA TGGAGTAAACCTAATTCTGCCCTTAATGTCACAAGATCTTTTGAAGTTTCCAACCCTTTGTAATCAATAT TACAAACTGATCACATTTATTTGTGAGATTTTTCCTGAAAAGATACCGCAGCTTCCTGAGGATCTGTTTA AGAGTCTGATGTACTCCCTAGAACTAGGGATGACATCAATGAGTTCAGAAGTATGCCAGCTTTGTCTCGA GGCCTTGACACCATTAGCTGAACAATGTGCTAAAGCACAAGAAACGGATTCACCACTTTTTCTAGCAACA CGACACTTCCTTAAGCTGGTTTTTGATATGCTGGTCTTGCAAAAGCACAACACGGAGATGACCACTGCAG CAGGCGAAGCATTCTACACATTGGTGTGTTTGCACCAGGCTGAATATTCTGAACTGGTTGAGACATTACT GTCAAGTCAACAAGACCCAGTCATTTACCAGAGATTAGCAGATGCCTTCAACAAGCTCACAGCGAGCAGC ACTCCTCCTGCCCTGGACCGGAAGCAGAAGATGGCCTTCCTAAAGAGTTTAGAAGAATTTATGGCAAATG TTGGTGGTCTCCTTTGTGTAAAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR220257 representing NM_020506
Red=Cloning site Green=Tags(s) MMAAALGPPEVIAQLENAAKVLMAPPSMVSNEQRQHAEHIFLSFRKSKSPFAVCRHILETSKVDYVLFQA ATAIMEAVVREWVLLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHE VSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQEEDLRQIFMLTVGVLQEFS RRENLSAQMSSVFQRYLALANQVLSWNFLPPNLGRHYIAMFESSQNVLLKPTESWREALLDSRVMELFFT VHRKIREDSDMAQDSLQCLAQLASLHGPIFPDEGSQVDYLAHFIEGLLNTINGIEIEDSEAVGISSIISN LITVFPRNVLTAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVRDDKHF HKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLASVGMLGRIAAE HCMPLLTSLLEERVTRLHGQLQRHQQQFLASPGSSTIDNKMLDDLYEDIHWLILVTGYLLADDTQGETPL IPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYSRTDSVIRLLSAVLRVSEVESRAIRADLTHLL SPQMGKDIVWFLKRWAKTYLLVDEKLYDQISLPLSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLA NDTVQLLVTLVERRERANLVIQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQ YWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLNNCIG LMEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMHLYEACLTLLQVYSKNNLGRQRIDVTAEEEQYQD LLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAAGRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQY YKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEALTPLAEQCAKAQETDSPLFLAT RHFLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASS TPPALDRKQKMAFLKSLEEFMANVGGLLCVK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_020506 |
| ORF Size | 3453 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_020506.2 |
| RefSeq Size | 3456 bp |
| RefSeq ORF | 3456 bp |
| Locus ID | 57258 |
| UniProt ID | Q9ESJ0 |
| MW | 130 kDa |
| Gene Summary | Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease
,null,
EBioMedicine
,PubMed ID 34388518
[Xpo4]
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Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC223741 | Xpo4 (untagged) - Mouse exportin 4 (Xpo4), (10ug) |
CNY 14,820.00 |
|
| MG220257 | Xpo4 (tGFP-tagged) - Mouse exportin 4 (Xpo4), (10ug) |
CNY 11,210.00 |
|
| MR220257L3 | Lenti ORF clone of Xpo4 (Myc-DDK-tagged) - Mouse exportin 4 (Xpo4) |
CNY 12,070.00 |
|
| MR220257L4 | Lenti ORF clone of Xpo4 (mGFP-tagged) - Mouse exportin 4 (Xpo4) |
CNY 12,070.00 |
