Ncoa1 (NM_010881) Mouse Tagged Lenti ORF Clone
CAT#: MR211972L4
- LentiORF®
Lenti ORF clone of Ncoa1 (mGFP-tagged) - Mouse nuclear receptor coactivator 1 (Ncoa1)
"NM_010881" in other vectors (3)
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CNY 12,730.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Synonyms | bHLHe74; KAT13A; mNRC-1; NCoA-1; NRC-1; SRC-1; SRC-a; SRC1 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR211972).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_010881 |
ORF Size | 4218 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_010881.1 |
RefSeq Size | 7346 bp |
RefSeq ORF | 4218 bp |
Locus ID | 17977 |
UniProt ID | P70365 |
Gene Summary | Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG211972 | Ncoa1 (tGFP-tagged) - Mouse nuclear receptor coactivator 1 (Ncoa1) |
CNY 11,880.00 |
|
MR211972 | Ncoa1 (Myc-DDK-tagged) - Mouse nuclear receptor coactivator 1 (Ncoa1) |
CNY 9,624.00 |
|
MR211972L3 | Lenti ORF clone of Ncoa1 (Myc-DDK-tagged) - Mouse nuclear receptor coactivator 1 (Ncoa1) |
CNY 12,730.00 |