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Hdac4 (NM_207225) Mouse Tagged ORF Clone
CAT＃: MR211598
- TrueORF®
Hdac4 (Myc-DDK-tagged) - Mouse histone deacetylase 4 (Hdac4)
ORF Plasmid: tGFP
"NM_207225" in other vectors (4)
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CNY 11,248.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 4932408F19Rik; HD4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR211598 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGCTCCCAAAGCCATCCAGATGGACTTTCTGGCCGAGACCAGCCTGTGGAGCTGCTGAATCCTGCCC GTGTGAACCACATGCCCAGCACGGTGGACGTGGCTACAGCGCTGCCTCTGCAAGTGGCCCCTACAGCAGT ACCCATGGACCTGCGCTTGGACCACCAGTTCTCACTGCCCTTGGAACCTGCATTGCGGGAGCAGCAACTG CAGCAGGAACTCCTAGCACTGAAACAGAAGCAGCAGATCCAGCGGCAGATACTCATTGCAGAGTTCCAGC GTCAACATGAGCAGTTGTCCCGACAGCATGAGGCACAGTTGCATGAACATATCAAGCAGCAGCAGGAGAT GCTGGCCATGAAGCACCAGCAGGAGCTGCTGGAGCACCAGCGGAAACTGGAGCGGCACCGGCAAGAGCAG GAGCTGGAGAAGCAGCACCGTGAGCAGAAGCTGCAGCAGCTCAAGAACAAGGAGAAGGGCAAAGAGAGTG CTGTGGCGAGCACAGAGGTGAAGATGAAGCTGCAGGAGTTTGTTCTCAACAAGAAGAAGGCTCTAGCCCA CCGGAACCTGAACCACTGCATTTCCAGCGATCCCCGCTACTGGTATGGGAAGACACAGCACAGCTCCCTT GACCAGAGCTCTCCACCCCAGAGTGGGGTGTCAGCCTCCTACAACCACCCCGTCTTGGGAATGTACGACG CCAAAGATGACTTCCCTCTTAGGAAAACAGCTTCTGAACCTAACCTGAAATTACGCTCAAGGCTTAAGCA GAAAGTAGCTGAGAGACGGAGCAGCCCCCTGTTGCGCAGGAAAGATGGCCCTGTGGCCACTGCTCTAAAA AAGCGACCCCTGGATGTTACAGACTCCGCATGCAGCAGCGCCCCTGGCTCCGGTCCCAGCTCTCCAAATA GCAGCTCTGGCAACGTCAGCACTGAGAATGGCATCGCACCCACTGTGCCCAGCGCTCCAGCTGAGACGAG CTTGGCACACAGACTTGTGACTCGAGAAGGCTCAGTCGCCCCACTTCCTCTCTACACGTCACCATCCTTA CCCAACATCACCTTGGGACTTCCTGCCACTGGCCCTGCCGCTGGTGCGGCAGGTCAGCAGGATGCTGAGA GGCTTGCTCTCCCAGCTCTCCAGCAGCGGATCTTGTTCCCTGGGACCCACCTCACCCCGTACCTGAGCAC CTCGCCCCTGGAGAGGGACGGTGCAGCAGCTCACAACCCCCTCCTGCAGCACATGGTCCTGCTGGAGCAG CCACCCACCCAGACACCCCTTGTCACAGGCCTGGGGGCGCTGCCCCTCCACTCACAGTCCCTGGTTGGTG CGGACAGGGTGTCCCCATCCATTCACAAGCTGCGGCAGCACCGCCCTCTGGGGCGCACGCAGTCAGCACC CCTGCCGCAGAACGCACAGGCCCTGCAGCACCTGGTGATCCAGCAGCAGCACCAGCAGTTCCTGGAGAAG CACAAGCAACAGTTCCAGCAGCAGCAGCTGCACCTCAGCAAGATAATCTCCAAACCTAGTGAGCCACCTC GGCAGCCTGAGAGCCACCCAGAGGAGACAGAGGAGGAGCTCCGTGAGCACCAGGCCTTGCTGGATGAGCC CTACCTAGATCGGCTACCTGGGCAGAAGGAGCCCTCCCTGGCTGGTGTGCAGGTGAAGCAGGAGCCCATT GAGAGTGAGGAGGAAGAAGCGGAGGCCACTCGAGAGACAGAGCCCGGCCAGCGCCCAGCCACTGAGCAGG AGCTGCTCTTCAGACAGCAAGCCCTCCTACTGGAGCAGCAGAGGATCCACCAGTTAAGAAACTACCAGGC ATCTATGGAGGCTGCTGGCATCCCTGTGTCATTTGGCAGCCACAGACCTCTGTCTCGGGCACAGTCCTCC CCAGCATCTGCCACCTTCCCCATGTCAGTCCAGGAGCCCCCCACCAAGCCAAGGTTCACCACAGGTCTTG TGTATGACACACTGATGTTGAAGCATCAGTGCACCTGTGGGAACACCAACAGCCACCCGGAGCATGCTGG GAGGATCCAGAGCATCTGGTCCCGCCTGCAGGAGACTGGACTCCGTGGCAAGTGTGAGTGCATCCGTGGA CGCAAGGCCACATTGGAGGAGCTGCAGACAGTGCACTCGGAGGCCCACACACTCCTCTACGGCACAAATC CTCTCAACAGACAGAAACTGGACAGCTCGCTGACCTCAGTGTTCGTCAGGCTTCCTTGTGGTGGTGTTGG GGTGGATAGCGACACCATATGGAATGAGGTGCACTCGTCTGGGGCAGCCCGCCTGGCTGTAGGCTGTGTA GTGGAGCTGGTCTTCAAGGTGGCCACGGGAGAGCTAAAGAATGGCTTTGCTGTGGTTCGTCCCCCAGGAC ACCATGCCGAGGAGAGCACACCCATGGGTTTCTGCTACTTTAACTCCGTGGCAGTTGCAGCCAAACTTCT CCAGCAGAGGCTGAATGTGAGCAAGATCCTCATTGTAGACTGGGATGTACATCATGGGAATGGGACCCAG CAGGCCTTCTACAATGACCCCAATGTTCTCTACATGTCCCTGCACCGCTATGACGATGGGAACTTCTTCC CAGGAAGTGGAGCACCAGATGAGGTGGGCACAGGGCCAGGCGTGGGTTTCAATGTCAACATGGCTTTCAC GGGTGGCCTCGAACCCCCCATGGGAGACGCTGAGTACTTGGCAGCCTTCAGAACGGTGGTTATGCCTATC GCAAATGAGTTTGCCCCAGATGTGGTACTGGTGTCATCGGGCTTCGATGCTGTGGAGGGCCACCCCACAC CTCTTGGAGGGTACAATCTCTCTGCCAAATGTTTTGGGTACTTGACAAAACAGCTGATGGGCTTAGCTGG TGGCCGGCTTGTGCTGGCCCTTGAGGGAGGCCATGACCTGACAGCCATCTGTGATGCTTCTGAAGCCTGC GTGTCTGCTCTGCTGGGAAACGAGCTTGAGCCTCTGCCAGAAAAGGTTCTACATCAGAGACCCAATGCCA ATGCTGTCCACTCCATGGAGAAAGTGATGGACATCCACAGCAAGTACTGGCGCTGCCTGCAGCGTCTGTC CTCCACGGTGGGGCACTCTCTGATTGAGGCGCAAAAGTGTGAGAAGGAAGAAGCTGAGACAGTCACCGCC ATGGCCTCGCTGTCTGTAGGCGTCAAACCTGCTGAGAAGAGATCTGAGGAGGAGCCCATGGAGGAGGAAC CACCACTG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR211598 protein sequence
Red=Cloning site Green=Tags(s) MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPTAVPMDLRLDHQFSLPLEPALREQQL QQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQ ELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSL DQSSPPQSGVSASYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVATALK KRPLDVTDSACSSAPGSGPSSPNSSSGNVSTENGIAPTVPSAPAETSLAHRLVTREGSVAPLPLYTSPSL PNITLGLPATGPAAGAAGQQDAERLALPALQQRILFPGTHLTPYLSTSPLERDGAAAHNPLLQHMVLLEQ PPTQTPLVTGLGALPLHSQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEK HKQQFQQQQLHLSKIISKPSEPPRQPESHPEETEEELREHQALLDEPYLDRLPGQKEPSLAGVQVKQEPI ESEEEEAEATRETEPGQRPATEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGSHRPLSRAQSS PASATFPMSVQEPPTKPRFTTGLVYDTLMLKHQCTCGNTNSHPEHAGRIQSIWSRLQETGLRGKCECIRG RKATLEELQTVHSEAHTLLYGTNPLNRQKLDSSLTSVFVRLPCGGVGVDSDTIWNEVHSSGAARLAVGCV VELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLNVSKILIVDWDVHHGNGTQ QAFYNDPNVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLEPPMGDAEYLAAFRTVVMPI ANEFAPDVVLVSSGFDAVEGHPTPLGGYNLSAKCFGYLTKQLMGLAGGRLVLALEGGHDLTAICDASEAC VSALLGNELEPLPEKVLHQRPNANAVHSMEKVMDIHSKYWRCLQRLSSTVGHSLIEAQKCEKEEAETVTA MASLSVGVKPAEKRSEEEPMEEEPPL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_207225 |
| ORF Size | 3231 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_207225.2 |
| RefSeq Size | 3960 bp |
| RefSeq ORF | 3231 bp |
| Locus ID | 208727 |
| UniProt ID | Q6NZM9 |
| MW | 118.6 kDa |
| Gene Summary | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Deacetylates HSPA1A and HSPA1A at 'Lys-77' leading to their preferential binding to co-chaperone STUB1.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A signalling pathway for transcriptional regulation of sleep amount in mice.
,null,
Nature
,PubMed ID 36477534
[Hdac4]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC202651 | Hdac4 (untagged) - Mouse histone deacetylase 4 (Hdac4), (10ug) |
CNY 11,248.00 |
|
| MG211598 | Hdac4 (tGFP-tagged) - Mouse histone deacetylase 4 (Hdac4) |
CNY 12,848.00 |
|
| MR211598L3 | Lenti ORF clone of Hdac4 (Myc-DDK-tagged) - Mouse histone deacetylase 4 (Hdac4) |
CNY 13,648.00 |
|
| MR211598L4 | Lenti ORF clone of Hdac4 (mGFP-tagged) - Mouse histone deacetylase 4 (Hdac4) |
CNY 13,648.00 |
