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Ldlrad4 (NM_172631) Mouse Tagged Lenti ORF Clone
CAT＃: MR204315L4
- LentiORF®
Lenti ORF clone of Ldlrad4 (mGFP-tagged) - Mouse DNA segment, Chr 18, ERATO Doi 653, expressed (D18Ertd653e)
"NM_172631" in other vectors (4)
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CNY 4,750.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | mGFP |
| Synonyms | 8230401C20Rik; A430083H02; A430108L08Rik; C18orf1; D18Ertd653e; D330030L18Rik |
| Vector | pLenti-C-mGFP-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR204315).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_172631 |
| ORF Size | 921 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_172631.2 |
| RefSeq Size | 2493 bp |
| RefSeq ORF | 921 bp |
| Locus ID | 52662 |
| UniProt ID | Q8BWJ4 |
| Gene Summary | Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC209900 | Ldlrad4 (untagged) - Mouse DNA segment, Chr 18, ERATO Doi 653, expressed (D18Ertd653e), (10ug) |
CNY 3,990.00 |
|
| MG204315 | Ldlrad4 (tGFP-tagged) - Mouse DNA segment, Chr 18, ERATO Doi 653, expressed (D18Ertd653e) |
CNY 2,850.00 |
|
| MR204315 | Ldlrad4 (Myc-DDK-tagged) - Mouse DNA segment, Chr 18, ERATO Doi 653, expressed (D18Ertd653e) |
CNY 1,416.00 |
|
| MR204315L3 | Lenti ORF clone of Ldlrad4 (Myc-DDK-tagged) - Mouse DNA segment, Chr 18, ERATO Doi 653, expressed (D18Ertd653e) |
CNY 4,750.00 |
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