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Maml1 (NM_175334) Mouse Tagged ORF Clone
CAT＃: MG221860
- TrueORF®
Maml1 (tGFP-tagged) - Mouse mastermind like 1 (Drosophila) (Maml1), (10ug)
ORF Plasmid: DDK
"NM_175334" in other vectors (4)
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CNY 9,220.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | AI644666; AW743257; D930008C07Rik; Mam-1; Mam1; mKIAA0200 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG221860 representing NM_175334
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTGCTACCCACCTGCCCCATGGCGGAGTTCGCGCTGCCGCGGCACAGCGCGGTCATGGAGCGCCTCC GCCGGCGCATCGAACTGTGCCGGCGCCACCACAGCACCTGTGAGGCCCGCTACGAGGCTGTGTCTCCCGA GCGCCTGGAGCTCGAGCGCCAGCACACCTTTGCCCTGCACCAGCGCTGCATCCAGGCCAAGGCCAAGCGC GCCGGCAAGCACCGGCAGCCGCCGGCCGCCGCCACGGCCCCGGTTGCCGCTCCGGCCCCCGCCTCGGCCC CGGCGGCCGCGCGCCTGGACGCAGCGGACGGCCCGGAGCACGGCCGCCCGGTCGCGCATCTTCATGATAC AGTGAAGAGGAGTCTTGACAGTGCTGCCTCCCCTCAGAATGGCGATCAACCAAATGGCTACGGAGACTTG TTTCCTGGGCATAAGAAGACACGCCGGGAGGCCCCTCTGGGGGTCAGTGTGTCTGCCAATGGGCTTCCTC CTGCCTCGCCCCTGGGCCAGCCCGACAAGCCTTCAGGGGGAGACACCCTGCAGACCGCTGGGAAGCACTC TCTGGGGCTCGATCCCATCAACAAGAAGTGTCTGGCAGACTCAGGCATCCACCTGAATGGAGGCAGCAAC TCCAGTGAGCCCTTTCCTCTAAGCCTGAGTAAAGAACTCAAGCAGGAGCCAGTGGACGACCTGCCGTGCA TGATCGCGGGCGCTGGAGGCTCCGTAGCTCAGAGCAACCTCATGCCGGACCTCAACCTTAATGAGCAGGA GTGGAAGGAGCTCATCGAGGAGCTCAACAGGTCAGTGCCCGACGAAGACATGAAGGACCTGTTTACGGAG GACTTTGAGGAGAAGAAGGATCCAGAGCCTCCTGGCTCTGCCACACAAACCCCCCTGGCCCAGGACATTA ATATTAAGACTGAGTTCTCTCCAGCAGCTTTTGAGCAGGAGCAGTTAGGTTCTCCACAAGTAAGGGCTGG GTCTGCAGGCCAGACCTTCCTAGGAGCCTCATCTGCCCCTGTGGGCACAGATTCTCCAAGCCTTGGGAGC TCTCAGACTCTGTTTCACACAACTAGTCAACCTGGGGTGGATAATTCCAGTCCAAACCTGATGCCGGCAT CAGCCCAGGCTCAAAGTGCACAAAGAGCCCTCACGAGTGTGGTATTACCTAGCCAGGGCCCAGGCGGGGC CTCGGAGCTGTCCTCTGCTCACCAGCTCCAGCAGATAGCTGCCAAGCAGAAGCGCGAGCAGATGTTGCAG AATCCCCAGCAAGCTGCCCCAGCACCCGGCCCAGGCCAGCTGGCCACGTGGCAGCAGGCAGGGCCCTCCC ACAGTCCCTTAGATGTTCCTTATCCCATGGAGAAGCCTGCCAGCCCTTCTGGCTACAAGCAAGACTTTAC CAACTCAAAACTGCTCATGATGCCCGGTGTGAACAAGAGTTCTCCTCGGCCAGGAGGCCCCTACCTCCAA CCTAGCCACTCCAACCTGCTGAGTCACCAGTCACCAAGTAACTTGAATCAGAACCCCGTGAATAACCAAG GGTCTGTGCTAGACTATGGCAATACAAAGCCCCTTTCTCATTACAAAGCAGACTGTGGCCAAGGTGGTCC TGGGTCTGGCCAGAACAAACCAGCTTTGATGGCATATCTTCCCCAGCAGCTGCCCCATCTGAGTAACGAG CAGAACTCCTTGTTTCTGATGAAACCAAAGTCAGGAAACATGCCCTTCCGGTCATTGGTTCCACCTGGCC AGGAGCAGAACCCTTCCAGTGTCCCTGTAGCTGCCCCAGCTGCCAGTGTGGGAACCCAGCCTACTGTGTC TGTGGCCAGCACTCACAACAGCTCGCCATACCTCAGCAGCCAGCAGCAGGCAGCTGTGATGAAGCAGCAC CAGCTGCTCCTGGACCAGCAGAAGCAGAGGGAGCAGCAGCAGCAGCAGCTGCAGCAGCAGCAGTTCCTGC AGAGGCAGCACCTCCTGGCTGAGCAGGAGAAACAACAGTTTCAGCGTCATCTGACCCGCCCACCCCCCCA GTACCAAGACCCAACACAAAGCACCTTCCCACAACAGGTTGGACAGTTCACAGGACCTTCTGCTGCTGTG CCTGGGATGAACAACTTGGGTCCGTCCAACTCCAGCTGTCCTCGAGTGTTCCCTCAGCCTGGGACTCTGA TGTCCATGGGCCCTGGACATGCCCCTGTCTCCTCTCTCCCCTCCAGCTCAGGCCAGCAGGACCGTGGAGT GGCCCAGTTTACTGGGTCCCAGAGTTTGCCTCAGAACAGCCTTTATGGCATGGCATCTGGCCTAGCCCAG ATAGTTGCCCAGCCCCCACCACAGGCTACCAGCACACATGCCCACATTCCACGGCAGACCAACGTGGGCC AGAACGCCTCCACCTCGGCTGCATATGGACAGAACTCTCTGGGGAGTGCCAGTCTTTCCCAGCAGCACAG TAAGGGAACCCTGCCTCCTGGTTTAACAAAGCCACAAGTCCCAAGGGTGTCAGCAGCCATGGGAAGCCAG AATGCCTCGTGGCAGCATCAGGGAATGCCAAACCTGAGCAGCCAGACGTCTGGGAACAGCAGTGTGAACC CCTTCACTGCAGCTCCCAGTTTCCACATACAGCAAGCCCACCTGAAACTAGCTGGCCAGCAGTTCTCCCA AGCCATGCCCAGCAGGCCCATGGCGCCTCTGAGTTCAGCAGGTGCAGCAGGGCCCATGCTGCCCCCAGTG AGTGCACAGCAGAGGAACAGTGCCCCTGCATCTGCACCTCCCCAAGCAGCCCCGCAGCAGGGCTTGCCTG GCTTAAGTCCTTCGGGGCCCGAGCTGGGGGCCTTCGGCCAGAGCCCCACCTCCCAGATGAGCGGCCGGCC AGGGCTACACTGTGCGCAGGCTTACCCTGTGAGGACCATGGGCCAAGAGCTGCCCTTTGCCTACAGCGGG CAGCCAGGTAGCAGTGGTCTGTCCAGTGTGGCTGGACACACTGACCTGATCGACTCGCTGCTGAAGAACA GGACTTCTGAGGAGTGGATCAATGAATTGGATGATCTTTTAGGGTCACAG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG221860 representing NM_175334
Red=Cloning site Green=Tags(s) MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKR AGKHRQPPAAATAPVAAPAPASAPAAARLDAADGPEHGRPVAHLHDTVKRSLDSAASPQNGDQPNGYGDL FPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSN SSEPFPLSLSKELKQEPVDDLPCMIAGAGGSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTE DFEEKKDPEPPGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGASSAPVGTDSPSLGS SQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQ NPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQDFTNSKLLMMPGVNKSSPRPGGPYLQ PSHSNLLSHQSPSNLNQNPVNNQGSVLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNE QNSLFLMKPKSGNMPFRSLVPPGQEQNPSSVPVAAPAASVGTQPTVSVASTHNSSPYLSSQQQAAVMKQH QLLLDQQKQREQQQQQLQQQQFLQRQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGPSAAV PGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYGMASGLAQ IVAQPPPQATSTHAHIPRQTNVGQNASTSAAYGQNSLGSASLSQQHSKGTLPPGLTKPQVPRVSAAMGSQ NASWQHQGMPNLSSQTSGNSSVNPFTAAPSFHIQQAHLKLAGQQFSQAMPSRPMAPLSSAGAAGPMLPPV SAQQRNSAPASAPPQAAPQQGLPGLSPSGPELGAFGQSPTSQMSGRPGLHCAQAYPVRTMGQELPFAYSG QPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_175334 |
| ORF Size | 3060 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_175334.3, NP_780543.2 |
| RefSeq Size | 5573 bp |
| RefSeq ORF | 3063 bp |
| Locus ID | 103806 |
| UniProt ID | Q6T264 |
| Gene Summary | Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC223244 | Maml1 (untagged) - Mouse mastermind like 1 (Drosophila) (Maml1), (10ug) |
CNY 13,210.00 |
|
| MR221860 | Maml1 (Myc-DDK-tagged) - Mouse mastermind like 1 (Drosophila) (Maml1) |
CNY 7,104.00 |
|
| MR221860L3 | Lenti ORF clone of Maml1 (Myc-DDK-tagged) - Mouse mastermind like 1 (Drosophila) (Maml1) |
CNY 10,260.00 |
|
| MR221860L4 | Lenti ORF clone of Maml1 (mGFP-tagged) - Mouse mastermind like 1 (Drosophila) (Maml1) |
CNY 10,260.00 |
