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Senp1 (NM_144851) Mouse Tagged ORF Clone
CAT＃: MG209692
- TrueORF®
Senp1 (tGFP-tagged) - Mouse SUMO1/sentrin specific peptidase 1 (Senp1)
ORF Plasmid: DDK
"NM_144851" in other vectors (4)
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CNY 5,040.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | 2310046A20Rik; D15Ertd528e; E330036L07Rik; suPr-2 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG209692 representing NM_144851
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATGACACAGCTGATGGGGTGAAGATGGACGCTGGGGAGGTGACCTTAGTGAACCACGGCTCCACTT TCAGAACCCACCGCCCGCCACAGTCAGGCTTTCCAGAGGAGCAGCTTCTGCTTTCTGACCAGCAGAGCTT GCCTTTCAGGCAGGGTACTTTAGATGGATCTTTCACGTGTTCTACAAGAAGCCCAGCCTATCGTCCAGAT TATCACTCAGATAACCCTTCCTCAGACAGTTTCCTTGGCTCAGGTGACGTAAGAACCTTTGGTCAAAGTG CAAATGGACAATGGAGAAATTCCACTCCAGCGTCAGGCTCAGCGCCACAAAAACCAAGAAATAGCCGAAG TCTTTGCCTCGAAACCCGGAAGACCTCAAGTGGATTATCAAACACCTTTGTGGGCAAGTCCAATCACCAC TGCCACATGTCTGCGTATGAAAAGTCATTTCCCATTAAGCCTGCCCCAAGTCCATCCTGGAGTGGGTCAT GTCGTCGGAGTCTTTTAAGCCCTAAGAAAACTCAGAGGCGACATTTCAGCACAGCAGAAGAGACAGTTCA AGAAGAAGAGAAGGAGATCTACAGACAGCTGCTGCAGATGGTCACAGGGAAGCAGTTCTGTGTAGCGAAA CCCACCACACATTTTCCGTTACGCCTGTCTCGGTGTCTTAGTTCCAATAAGAACTCTTTGAAAGACTCGC TGTTGAGAAACGGAAACTCTTGTGCATCTCATGTCATTGGTTCTGATACGTCATCCTCTGGATCTGCCAG CATTTTAACTGCACAGGAGCAGTTGTCCCACAGTGCACATTCCCTGTCATCTGGTACCCCAGATGTTGCC TTTGGATCCAAAGACTCTGATCCTCACCATCACCTCGCTGCACCTCATCAGCCAAATAGCTTACCAGCAT CAAATACACAGTCCGAAGGGTCAGACTCTGTGATTTTACTTAAAGTGAAAGAATCTCAGACTCCAGCTTC CAGCCCTACGTTCTTCCAGGCAGAGCTATGGATCAAAGAATTAACTAGCGTTTATGACTCTCGAGCTCGG GAAAGATTGCGCCGGATTGAAGAGCAGAAAGCATTGGCACTACAGCTTCAAAACCAGCGACTGCAGGAGC AGGAACATGCAGTACTTGACTCCGTAGAGCTTCACCTTCGTGTGCCTCTTGAAAAGGAGATTCCTGTCAC AGCTGCCCAAGAAACCAGGAAAAAAAGCCACCAGCTGACTGACAGTGAAGACGAATTTCCTGAAATTACA GAGGAAATGGAAAAAGAAATAAAGAATGTATTTCGTAACGGTAACCAGGATGAAGTCCTCAGTGAGGCAT TCCGCTTGACCATTACACGCAAAGACATTCAGACTCTAAACCATCTAAACTGGCTCAATGATGAGATCAT CAATTTCTACATGAACATGCTAATGGAACGCAGTAAAGAGAAGGGGTTTCCAAGTGTACATGCGTTTAAT ACCTTCTTCTTCACTAAGCTAAAAACAGCTGGTTATCAGGCAGTGAAACGCTGGACAAAGAAGGTGGATG TATTCTCCGTTGATATTCTTCTGGTGCCCATTCACTTGGGTGTGCACTGGTGTCTAGCTGTTGTAGACTT TAGAAGGAAGAGTATCACCTACTATGATTCTATGGGTGGAATAAACAACGAGGCCTGCAGGATCCTCTTG CAATACCTAAAACAAGAAAGTGTTGACAAGAAAAGGAAAGAGTTTGACACCAACGGCTGGCAGCTCTTCA GCAAGAAGAGCCAGGAAATCCCACAGCAGATGAATGGGAGTGACTGTGGAATGTTTGCTTGCAAATATGC TGACTGCATTACCAAAGACAGACCAATCAACTTCACACAGCAACACATGCCATATTTCCGAAAGCGAATG GTCTGGGAGATCCTCCACCGGAAGCTCTTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG209692 representing NM_144851
Red=Cloning site Green=Tags(s) MDDTADGVKMDAGEVTLVNHGSTFRTHRPPQSGFPEEQLLLSDQQSLPFRQGTLDGSFTCSTRSPAYRPD YHSDNPSSDSFLGSGDVRTFGQSANGQWRNSTPASGSAPQKPRNSRSLCLETRKTSSGLSNTFVGKSNHH CHMSAYEKSFPIKPAPSPSWSGSCRRSLLSPKKTQRRHFSTAEETVQEEEKEIYRQLLQMVTGKQFCVAK PTTHFPLRLSRCLSSNKNSLKDSLLRNGNSCASHVIGSDTSSSGSASILTAQEQLSHSAHSLSSGTPDVA FGSKDSDPHHHLAAPHQPNSLPASNTQSEGSDSVILLKVKESQTPASSPTFFQAELWIKELTSVYDSRAR ERLRRIEEQKALALQLQNQRLQEQEHAVLDSVELHLRVPLEKEIPVTAAQETRKKSHQLTDSEDEFPEIT EEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGFPSVHAFN TFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRRKSITYYDSMGGINNEACRILL QYLKQESVDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRM VWEILHRKLL TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_144851 |
| ORF Size | 1920 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_144851.5, NP_659100.1 |
| RefSeq Size | 6415 bp |
| RefSeq ORF | 1923 bp |
| Locus ID | 223870 |
| UniProt ID | P59110 |
| Gene Summary | Protease that catalyzes two essential functions in the SUMO pathway (PubMed:15923632, PubMed:29499132). The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. Deconjugates SUMO1 from HIPK2 (By similarity). Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity (By similarity). Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity (By similarity). Deconjugates SUMO2 from MTA1 (By similarity). Deconjugates SUMO2 from MTA1 (By similarity). Deconjugates SUMO1 from METTL3 (By similarity). Desumoylates CCAR2 which decreases its interaction with SIRT1 (By similarity). Deconjugates SUMO1 from GPS2 (PubMed:29499132).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes.
,null,
Neuron
,PubMed ID 32735781
[Senp1]
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Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC204079 | Senp1 (untagged) - Mouse SUMO1/sentrin specific peptidase 1 (Senp1), (10ug) |
CNY 4,776.00 |
|
| MR209692 | Senp1 (Myc-DDK-tagged) - Mouse SUMO1/sentrin specific peptidase 1 (Senp1) |
CNY 4,768.00 |
|
| MR209692L3 | Lenti ORF clone of Senp1 (Myc-DDK-tagged) - Mouse SUMO1/sentrin specific peptidase 1 (Senp1) |
CNY 6,460.00 |
|
| MR209692L4 | Lenti ORF clone of Senp1 (mGFP-tagged) - Mouse SUMO1/sentrin specific peptidase 1 (Senp1) |
CNY 6,460.00 |
