Reln (NM_011261) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	reeler; rl
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >MC229774 representing NM_011261 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGCGCGGCTGCTGGGCGCCGCGGGCTCTCGTCCTGGCCGTGCTGCTGCTGCTGGCGACGCTGAGGG CGCGCGCGGCCACCGGCTACTACCCGCGCTTCTCGCCTTTCTTTTTCCTGTGCACCCACCACGGGGAGCT GGAAGGGGATGGGGAGCAGGGCGAGGTGCTCATTTCCCTGCACATTGCGGGCAACCCCACCTACTACGTA CCGGGACAGGAATACCATGTTACAATTTCAACAAGCACCTTCTTTGATGGCTTGCTGGTGACGGGACTCT ATACCTCGACAAGCATCCAGTCTTCTCAGAGCATTGGAGGCTCCAGCGCCTTTGGATTCGGGATCATGTC CGACCACCAGTTTGGTAACCAGTTTATGTGCAGTGTGGTGGCCTCTCATGTGAGTCACCTGCCTACAACC AACCTCAGCTTTGTCTGGATTGCCCCACCAGCTGGCACAGGCTGTGTGAATTTCATGGCTACTGCAACAC ATAGGGGCCAGGTGATTTTCAAAGACGCACTGGCCCAGCAGCTGTGTGAACAAGGAGCTCCCACAGAGGC CACTGCTTACTCGCACCTTGCTGAAATACACAGTGACAGTGTGATCCTACGAGATGACTTTGACTCCTAC CAGCAACTGGAATTGAACCCCAACATATGGGTTGAATGCAGCAACTGTGAGATGGGAGAGCAGTGTGGCA CCATCATGCATGGCAATGCTGTCACCTTCTGTGAGCCGTACGGCCCTCGAGAGCTGACCACCACATGCCT GAACACAACAACAGCATCTGTCCTCCAGTTTTCCATTGGGTCAGGATCATGTCGATTTAGTTACTCTGAC CCCAGCATCACTGTGTCATACGCCAAGAACAATACCGCTGATTGGATTCAGCTGGAGAAAATTAGAGCCC CTTCCAATGTGAGCACAGTCATCCACATCCTGTACCTCCCCGAGGAAGCCAAAGGGGAGAGCGTGCAGTT CCAGTGGAAACAGGACAGCCTGCGAGTGGGTGAGGTGTATGAGGCCTGCTGGGCCCTGGATAACATCCTG GTCATCAATTCAGCCCACAGAGAAGTCGTTCTGGAGGACAACCTCGACCCGGTCGACACGGGCAACTGGC TCTTCTTCCCTGGAGCAACGGTCAAGCATAGCTGTCAGTCAGATGGGAACTCCATTTATTTCCATGGAAA TGAAGGCAGCGAGTTCAATTTTGCCACCACCCGGGATGTAGATCTTTCTACAGAGGATATTCAAGAGCAG TGGTCAGAAGAATTTGAGAGCCAGCCCACAGGATGGGATATCTTGGGAGCAGTAGTTGGTGCAGACTGTG GAACCGTAGAATCAGGACTATCACTGGTGTTCCTCAAAGATGGAGAGAGGAAGCTTTGCACCCCCTACAT GGATACAACTGGTTATGGCAACCTGAGGTTCTACTTCGTTATGGGAGGAATCTGTGACCCTGGAGTCTCT CATGAAAACGATATCATCTTATATGCAAAGATTGAAGGAAGAAAAGAACACATTGCACTGGACACTCTTA CCTATTCTTCCTATAAGGTTCCGTCTTTGGTTTCTGTGGTCATCAACCCTGAACTTCAGACACCTGCCAC CAAATTTTGTCTCAGGCAAAAGAGCCACCAAGGGTATAATCGGAATGTCTGGGCTGTGGACTTCTTCCAT GTGCTGCCCGTTCTCCCTTCAACAATGTCTCACATGATCCAGTTTTCTATTAATTTGGGATGCGGCACAC ACCAGCCTGGGAACAGCGTCAGCTTGGAGTTTTCTACTAACCATGGACGGTCCTGGTCCCTACTCCACAC TGAGTGCTTGCCGGAGATCTGTGCAGGCCCCCACCTCCCCCACAGCACTGTCTACTCCTCAGAAAACTAC AGCGGGTGGAACCGAATCACGATTCCTCTCCCTAATGCAGCACTCACCCGAGACACCAGGATTCGCTGGA GACAAACAGGCCCAATCCTGGGAAATATGTGGGCAATTGATAATGTTTATATAGGTCCTTCGTGTCTCAA ATTCTGTTCTGGCAGAGGACAATGCACTCGGCATGGCTGCAAGTGTGACCCAGGATTTTCTGGCCCAGCT TGTGAGATGGCATCTCAGACATTCCCAATGTTTATTTCGGAAAGCTTTGGCAGTGCCAGACTTTCCTCTT ACCATAACTTTTACTCTATCCGTGGTGCTGAAGTCAGCTTTGGTTGTGGTGTCTTAGCCAGTGGTAAGGC TCTGGTTTTCAACAAAGATGGGAGGCGGCAGCTAATCACGTCCTTTCTGGACAGCTCGCAGTCCAGGTTT CTTCAGTTTACACTGAGGCTGGGGAGCAAGTCTGTGCTGAGCACGTGCAGAGCCCCTGACCAGCCGGGGG AGGGAGTCCTGCTGCACTATTCATATGACAACGGGATAACATGGAAACTCCTGGAGCACTATTCCTACGT CAACTACCACGAGCCCAGAATAATCTCTGTAGAGCTACCGGATGATGCAAGACAGTTTGGAATCCAGTTC AGATGGTGGCAGCCTTACCATTCTTCCCAAGGAGAAGACGTGTGGGCCATTGATGAGATTGTCATGACCT CAGTCCTGTTCAACAGCATCAGTCTCGACTTTACCAATCTTGTGGAAGTCACTCAATCCCTGGGATTCTA CCTTGGCAATGTTCAACCATACTGTGGCCATGACTGGACGCTTTGTTTTACGGGAGATTCTAAACTTGCC TCAAGCATGCGCTATGTGGAAACACAGTCCATGCAGATCGGAGCATCCTATATGATTCAGTTCAGCCTAG TGATGGGATGTGGCCAGAAATACACTCCTCACATGGACAACCAGGTGAAGCTGGAGTACTCAGCCAACCA CGGCCTTACATGGCACCTTGTACAAGAAGAATGCCTTCCCAGTATGCCAAGCTGCCAGGAATTTACATCT GCCAGCATTTACCATGCCAGCGAGTTCACACAGTGGAGAAGAGTCACTGTTGTTCTTCCCCAGAAAACAT GGTCCGGTGCCACCCGCTTCCGTTGGAGTCAGAGCTATTACACAGCCCAGGATGAGTGGGCTTTAGACAA CATTTACATTGGGCAGCAGTGCCCCAACATGTGCAGTGGGCATGGCTCATGTGACCATGGCGTGTGCAGG TGTGACCAGGGATACCAGGGCACTGAATGCCACCCAGAAGCTGCACTTCCTTCCACGATTATGTCAGATT TTGAGAACCCGAGCAGTTGGGAATCAGACTGGCAGGAAGTTATTGGGGGAGAAGTTGTAAAGCCTGAGCA AGGCTGTGGAGTCGTGTCTTCTGGATCTTCTCTGTACTTCAGCAAGGCTGGGAAGAGGCAGCTGGTGAGC TGGGACCTGGACACATCCTGGGTGGACTTTGTCCAGTTCTACATCCAGATAGGAGGAGAGAGTGCTGCAT GCAACAAGCCTGACAGCAGAGAGGAGGGCATTCTGCTCCAGTATAGCAACAACGGGGGCATCCAGTGGCA CCTGCTGGCAGAGATGTACTTCTCAGACTTCAGCAAACCCAGATTTGTCTACCTGGAGCTCCCAGCTGCT GCGAAGACCCCTTGTACCAGGTTCCGCTGGTGGCAGCCTGTGTTCTCGGGGGAGGACTATGACCAGTGGG CCGTTGATGATATCATCATTCTGTCAGAGAAGCAGAAGCAGGTTATTCCAGTTGTCAACCCAACTTTGCC CCAGAACTTCTATGAGAAGCCAGCTTTCGATTACCCTATGAACCAAATGAGTGTGTGGCTAATGTTGGCC AATGAAGGCATGGCTAAAAACGACAGCTTCTGTGCGACCACGCCGTCAGCCATGGTGTTTGGAAAGTCAG ATGGAGACCGGTTTGCAGTAACTCGAGATCTGACCCTGAAACCTGGATATGTGCTGCAGTTCAAGCTAAA CATAGGCTGCACCAGCCAGTTCAGCAGCACTGCCCCGGTTCTCCTGCAGTATTCACATGATGCCGGCATG TCGTGGTTTCTGGTGAAGGAAGGATGCTTCCCAGCGTCAGCAGGCAAAGGATGTGAAGGGAACTCCAGGG AATTGAGTGAGCCTACTGTCTATTATACTGGGGACTTCGAAGAATGGACTAGAATCACCATTGCCATTCC AAGGTCCCTTGCATCCAGCAAGACCAGATTCCGATGGATCCAAGAGAGCAGCTCTCAGAAGAATGTGCCC CCGTTTGGCTTAGATGGGGTGTACATATCTGAGCCTTGTCCCAGTTACTGCAGTGGCCATGGAGACTGCA TCTCGGGGGTGTGTTTTTGTGACCTGGGGTACACAGCTGCACAAGGAACCTGTGTGTCAAACACCCCTAA CCACAGTGAGATGTTCGACAGGTTTGAGGGGAAGCTAAGCCCACTGTGGTACAAAATCACCGGGGGTCAG GTTGGCACGGGCTGTGGCACCCTCAATGACGGCAGGTCCCTCTACTTTAATGGCCTTGGGAAAAGGGAAG CCAGGACAGTCCCACTGGACACCAGGAATATCAGACTTGTTCAGTTTTATATACAAATTGGAAGTAAAAC ATCAGGGATTACGTGCATCAAACCACGGGCTAGAAATGAGGGGCTTGTTGTTCAGTATTCCAATGATAAT GGGATACTTTGGCATTTGCTGAGAGAGTTGGATTTCATGTCATTCCTGGAGCCACAGATCATTTCCATTG ACCTGCCCCGGGAAGCAAAGACACCTGCCACAGCTTTCCGGTGGTGGCAGCCGCAGCATGGGAAGCATTC GGCCCAGTGGGCTTTGGATGATGTCCTTATAGGAGTGAATGACAGCTCTCAAACTGGATTTCAAGATAAA TTTGATGGCTCCATAGACTTGCAAGCCAACTGGTATCGAATCCAGGGAGGCCAAGTTGATATCGACTGCC TCTCTATGGACACTGCCCTTATATTCACTGAAAACATAGGAAAACCTCGCTATGCTGAGACCTGGGACTT CCATGTGTCAGCGTCAAGCTTCTTACAGTTTGAAATGAACATGGGCTGCAGCAAGCCTTTCAGTGGTGCC CACGGCATACAGCTCCAGTACTCTCTGAACAACGGCAAGGACTGGCAGCTTGTCACCGAAGAGTGTGTCC CTCCAACCATTGGCTGCGTGCACTACACAGAGAGTTCAACTTACACATCAGAAAGATTCCAGAACTGGAG GCGGGTCACGGTCTACCTGCCACTCGCCACCAATTCTCCCAGGACTCGGTTCAGATGGATTCAGACCAAC TATACTGTTGGAGCAGATTCCTGGGCTATTGATAATGTCATCCTGGCCTCGGGCTGTCCTTGGATGTGCT CAGGACGAGGGATCTGTGATTCGGGGCGCTGTGTGTGTGACCGGGGCTTCGGTGGACCCTTCTGTGTTCC TGTTGTTCCTCTTCCCTCCATTCTAAAAGATGATTTCAATGGGAACTTACATCCTGACCTTTGGCCTGAA GTGTACGGGGCAGAGAGGGGCAATCTGAATGGCGAAACCATCAAATCCGGAACATGTCTGATCTTTAAAG GGGAGGGACTAAGAATGCTTATTTCCAGAGATCTAGATTGCACCAATACTATGTATGTCCAGTTCTCTCT CCGATTTATAGCGAAAGGTACCCCAGAGAGGTCTCACTCCATCCTTCTACAGTTCTCTGTCAGTGGAGGA GTCACCTGGCACCTGATGGATGAATTCTACTTCCCTCAAACGACCAGCATACTTTTCATCAATGTTCCCT TACCATACGGTGCCCAAACCAACGCTACAAGATTCAGACTCTGGCAACCGTACAATAATGGTAAGAAAGA AGAAATCTGGATCATTGATGACTTTATTATTGATGGAAACAATTTGAACAACCCCGTGCTGCTGCTGGAC ACGTTCGACTTTGGGCCCAGGGAAGACAATTGGTTTTTCTATCCGGGTGGTAATATCGGACTTTACTGCC CGTATTCTTCAAAGGGAGCTCCTGAGGAGGATTCGGCCATGGTGTTTGTTTCAAACGAAGTTGGAGAACA CTCCATTACCACACGAGACCTAAGTGTGAACGAGAACACCATCATTCAATTTGAGATCAATGTTGGCTGC TCCACTGATAGTTCTTCTGCTGATCCGGTCAGACTGGAATTCTCAAGGGACTTTGGAGCCACCTGGCACC TGCTGCTGCCTCTCTGCTACCACAGCAGCAGCCTCGTCAGCTCCTTATGCTCCACTGAGCATCACCCGAG CAGCACCTACTACGCGGGGACCACCCAGGGCTGGCGGCGGGAGGTCGTGCACTTCGGAAAGCTGCACCTT TGTGGATCTGTGCGTTTCCGTTGGTACCAGGGATTTTATCCTGCTGGCTCTCAGCCGGTCACATGGGCCA TTGACAATGTCTACATTGGTCCCCAGTGTGAAGAGATGTGCTATGGGCACGGGAGCTGCATCAATGGAAC CAAGTGTATATGTGACCCGGGCTACTCTGGGCCAACCTGTAAAATAAGCACCAAAAATCCTGATTTTCTC AAAGACGACTTTGAAGGTCAACTGGAATCCGATCGATTCTTACTGATGAGCGGTGGGAAGCCGTCTCGTA AGTGTGGCATCCTTTCCAGTGGGAACAACCTCTTCTTCAATGAGGACGGCTTGCGCATGCTAGTAACACG GGACCTGGATTTATCACATGCAAGGTTTGTGCAGTTCTTCATGAGACTGGGATGTGGTAAAGGTGTTCCA GACCCCAGGAGCCAGCCCGTGCTTCTGCAGTACTCCCTCAATGGCGGCCTCTCCTGGAGTCTTCTTCAAG AGTTCCTCTTCAGCAACTCCAGCAATGTGGGCAGGTACATTGCCCTGGAAATGCCCCTGAAAGCCCGTTC TGGTTCGACACGCCTCCGCTGGTGGCAGCCATCTGAAAATGGGCACTTCTATAGCCCCTGGGTGATCGAC CAGATTCTTATTGGAGGAAATATCTCTGGTAATACAGTCTTAGAAGATGATTTCTCAACTCTGGACAGCA GAAAGTGGCTGCTTCACCCAGGAGGCACCAAGATGCCTGTGTGTGGCTCCACAGGCGATGCCCTGGTCTT TATTGAAAAGGCCAGCACCCGTTACGTGGTCACGACAGACATCGCTGTGAATGAGGACTCATTCCTACAG ATAGACTTTGCTGCCTCCTGCTCAGTCACAGACTCCTGCTATGCTATTGAACTGGAGTACTCGGTGGATC TCGGTCTGTCGTGGCACCCGCTGGTGAGGGACTGCCTGCCTACCAATGTTGAGTGTAGTCGTTACCACCT GCAGCGGATCCTGGTGTCAGATACTTTCAACAAGTGGACCAGAATCACTCTGCCCCTGCCTTCCTACACC AGGTCTCAAGCCACTCGTTTCCGCTGGCATCAGCCAGCGCCTTTTGACAAGCAGCAGACCTGGGCAATAG ATAATGTCTATATTGGGGATGGTTGCCTAGACATGTGCAGTGGCCACGGGAGATGCGTCCAGGGAAGCTG TGTCTGTGATGAACAGTGGGGAGGCCTGTACTGTGATGAGCCTGAGACCTCCCTTCCCACCCAGCTCAAA GACAACTTCAACCGAGCCCCCTCCAACCAGAACTGGCTGACTGTGAGCGGTGGGAAGCTGAGTACAGTGT GTGGGGCTGTGGCTTCCGGCCTGGCTCTCCATTTCAGTGGGGGCTGCAGCCGATTGTTAGTCACTGTGGA TCTGAACCTCACCAATGCTGAGTTTATCCAGTTTTACTTTATGTATGGATGCCTCATTACGCCGAGCAAC CGTAACCAGGGAGTCCTGCTGGAGTACTCTGTCAATGGAGGCATCACCTGGAACTTGCTGATGGAGATTT TCTATGACCAGTACAGCAAACCTGGATTTGTGAATATCCTTCTCCCTCCTGATGCTAAAGAGATTGCCAC TCGCTTCCGATGGTGGCAGCCACGACATGATGGCCTTGACCAGAATGACTGGGCCATTGACAATGTCCTC ATCTCGGGCTCTGCGGACCAGAGGACAGTCATGCTGGACACCTTTAGCAGCGCCCCAGTACCACAGCATG AGCGCTCCCCCGCAGACGCTGGCCCTGTTGGAAGAATTGCTTTTGAAATGTTCTTAGAAGACAAAACTTC AGTGAATGAGAATTGGCTCTTCCATGATGACTGTACAGTGGAAAGATTCTGTGACTCGCCAGATGGTGTC ATGCTCTGTGGCAGCCATGATGGACGAGAGGTGTATGCAGTGACTCATGACCTGACGCCCACTGAGAACT GGATCATGCAGTTCAAGATCTCTGTTGGATGCAAAGTGCCTGAAAAAATTGCCCAGAATCAAATTCACGT GCAGTTTTCTACTGACTTTGGCGTGAGCTGGAGTTATTTAGTCCCTCAGTGCTTACCCGCCGACCCAAAG TGTTCTGGAAGCGTTTCTCAACCGTCTGTGTTCTTCCCAACTGAAGGGTGGAAAAGGATCACCTACCCGC TTCCTGAAAGCTTAACGGGGAATCCTGTAAGATTTAGGTTCTACCAAAAGTACTCAGATGTGCAGTGGGC AATTGACAATTTCTACCTTGGCCCTGGATGTTTGGACAACTGTGGAGGCCACGGAGACTGCCTAAAGGAA CAGTGTATCTGTGACCCAGGCTACTCAGGGCCAAACTGCTACTTAACTCACAGCCTGAAGACTTTCCTGA AGGAGCGCTTTGACAGTGAGGAGATCAAGCCTGACTTATGGATGTCCTTGGAAGGCGGAAGCACTTGTAC AGAGTGCGGGGTCCTCGCCGAGAACACTGCACTCTATTTTGGGGGATCCACTGTGAGACAAGCTATTACT CAAGACTTAGATCTCAGAGGTGCAAAATTCCTGCAGTACTGGGGACGTATCGGCAGTGAGAACAACATGA CATCTTGCCATCGGCCTGTCTGCCGGAAGGAAGGCGTGCTGCTGGACTTCTCTACGGATGGAGGAATCAC TTGGACCTTGCTTCACGAGATGGATTTCCAGAAATACATTTCTGTGAGGCACGACTACATCCTCCTGCCT GAGGGGGCCCTCACCAACACAACTCGACTTCGCTGGTGGCAGCCTTTTGTCATCAGCAATGGGCTCGTGG TTTCCGGGGTGGAGCGTGCGCAGTGGGCACTGGACAACATTCTGATTGGTGGAGCAGAAATCAATCCAAG CCAACTGGTGGACACTTTCGATGACGAAGGCTCCTCCCATGAAGAAAACTGGAGTTTTTACCCTAATGCA GTAAGGACAGCAGGATTCTGTGGCAACCCATCCTTCCACCTCTACTGGCCAAATAAAAAGAAGGACAAGA CCCACAATGCACTCTCCTCCCGAGAGCTCATTATACAGCCAGGATACATGATGCAATTTAAAATTGTGGT GGGTTGTGAAGCCACTTCATGTGGTGACCTTCATTCCGTGATGCTGGAGTACACCAAGGATGCAAGGTCC GATTCCTGGCAGCTCGTGCAGACCCAGTGCCTACCTTCCTCTTCCAATAGCATTGGCTGCTCCCCGTTCC AGTTCCATGAAGCCACCATTTATAATGCTGTCAACAGCTCAAGCTGGAAGAGGATCACCATCCAGCTCCC AGACCACGTCTCGTCAAGTGCCACACAGTTCCGCTGGATCCAGAAGGGAGAAGAAACCGAGAAGCAAAGC TGGGCCATCGACCACGTGTACATCGGAGAGGCTTGTCCCAAGCTCTGCAGCGGGCATGGCTACTGCACCA CAGGGGCCGTCTGCATCTGCGATGAAAGCTTCCAAGGTGACGACTGCTCTGTCTTCAGTCACGAGCTTCC TAGTTACATTAAAGATAATTTTGAATCAGCAAGAGTCACTGAAGCCAACTGGGAAACCATCCAGGGTGGA GTGATCGGAAGTGGCTGTGGGCAGCTGGCGCCCTATGCCCATGGAGATTCGCTCTACTTTAATGGTTGTC AGATAAGGCAAGCTGCCACCAAGCCACTGGACCTCACTCGAGCAAGCAAAATTATGTTTGTCTTGCAAAT TGGGAGCCCAGCCCAGACAGACAGTTGCAACAGCGACCTCAGCGGCCCCCACACCGTGGACAAAGCAGTA CTGCTGCAGTACAGTGTCAACAATGGCATCACCTGGCACGTCATCGCTCAGCACCAGCCGAAGGACTTCA CACAAGCTCAGCGGGTGTCTTACAACGTCCCCCTGGAAGCTCGGATGAAAGGAGTTCTACTGCGCTGGTG GCAGCCACGCCACAATGGAACAGGTCATGATCAATGGGCTTTGGACCATGTGGAGGTCGTCCTAGTAAGC ACTCGCAAACAAAATTACATGATGAATTTTTCACGGCAACATGGGCTCAGGCACTTCTACAACAGAAGAC GAAGGTCGCTTAGGCGATACCCATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_011261
Insert Size	10386 bp
OTI Disclaimer	Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_011261.2, NP_035391.2
RefSeq Size	11702 bp
RefSeq ORF	10386 bp
Locus ID	19699
UniProt ID	Q60841
Gene Summary	Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

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