Il17re (NM_001034031) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	AA589509; IL-17RE; Il25r
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >MC227691 representing NM_001034031 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTGCATAGAGGCCTCCTACCTGCAAGAGGACACTGTGAGGCGCAAAAAGTGTCCCTTCCAGAGCTGGC CTGAAGCTTATGGCTCAGACTTCTGGCAGTCAATACGCTTCACTGACTACAGCCAGCACAATCAGATGGT CATGGCTCTGACACTCCGCTGCCCACTGAAACTGGAGGCCTCCCTCTGCTGGAGGCAGGACCCACTCACA CCCTGCGAAACCCTTCCCAACGCCACAGCACAGGAGTCAGAAGGATGGTATATCCTGGAGAATGTGGACT TGCACCCCCAGCTCTGCTTTAAGTTCTCATTTGAAAACAGCAGCCACGTTGAATGTCCCCACCAGAGTGG CTCTCTCCCATCCTGGACTGTGAGCATGGATACCCAGGCCCAGCAGCTGACGCTTCACTTTTCTTCGAGG ACATATGCCACCTTCAGTGCTGCCTGGAGTGACCCAGGTTTGGGGCCGGATACCCCCATGCCTCCTGTGT ACAGCATCAGCCAGACCCAGGGCTCAGTCCCAGTGACGCTAGACCTCATCATCCCCTTCCTGAGGCAGGA GAATTGCATCCTGGTGTGGAGGTCAGATGTCCATTTTGCCTGGAAGCACGTCTTGTGTCCTGATGTCTCC CATAGACACCTCGGGCTCTTGATCCTGGCACTGCTGGCTCTCACCGCTCTAGTGGGTGTAGTTCTGGTCC TCCTCGGCCGGCGCCTACTGCCAGGCTCCGGTCGAACAAGGCCAGTTTTACTCCTACATGCAGCGGACTC AGAGGCACAGCGACGCCTGGTGGGAGCTTTGGCCGAACTGCTGCGGACGGCGCTGGGAGGTGGACGCGAC GTGATCGTGGATCTCTGGGAAGGGACGCACGTAGCACGCATTGGACCACTGCCGTGGCTTTGGGCAGCGC GGGAGCGCGTGGCGCGGGAGCAGGGCACAGTGCTGCTCCTGTGGAACTGTGCGGGTCCCAGCACCGCCTG CAGCGGTGACCCGCAGGCTGCGTCCCTTCGCACCTTGTTGTGCGCTGCTCCACGTCCGCTGCTGCTCGCC TACTTCAGTCGCCTCTGCGCCAAAGGTGACATCCCCCGGCCGCTGCGCGCTCTGCCACGCTACCGCCTGC TTCGTGACCTGCCGCGCCTGCTGAGAGCACTGGATGCTCAGCCTGCCACCCTAGCCTCCAGCTGGAGTCA CCTTGGGGCTAAGCGGTGCTTGAAAAACCGTCTGGAGCAGTGTCACCTGCTGGAACTTGAGGCTGCCAAA GATGACTACCAAGGCTCAACCAATAGTCCCTGTGGTTTCAGCTGTCTGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001034031
Insert Size	1311 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001034031.1, NP_001029203.1
RefSeq Size	1973 bp
RefSeq ORF	1311 bp
Locus ID	57890
UniProt ID	Q8BH06
Gene Summary	Specific functional receptor for IL17C, signaling through the NF-kappa-B and MAPK pathways. Requires TRAF3IP2 /ACT1 for signaling. Crucial regulator in innate immunity to bacterial pathogens, such as Citrobacter rodentium. Isoform 4 and isoform 5 may be either cytoplasmic inactive or dominant active forms. Isoform 2 and isoform 3 may act as soluble decoy receptors.[UniProtKB/Swiss-Prot Function]

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