Myo18a (NM_011586) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	MAJN; MyoPDZ; MysPDZ; SP-R210
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >MC225142 representing NM_011586 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTTTAACCTCATGAAGAAAGATAAGGACAAAGATGGCGGGCGGAAGGAGAAGAAGGAAAAAAAGGAGA AGAAGGAGAGGATGTCTGCGGCAGAACTGCGGAGCCTGGAAGAGATGAGCATGCGCCGTGGCTTTTTCAA CTTGAACCGGTCCTCCAAGCGGGAATCTAAGACGCGCCTGGAAATCTCCAACCCCATCCCTATCAAGGTG GCCAGTGGCTCTGACCTGCACCTGACGGACATTGACTCTGACAGCAATCGGGGTAGCATCATCCTGGACT CAGGACACCTAAGCACAGCCAGCTCCAGTGATGACCTCAAGGGTGAAGAAGGCAGCTTCCGGGGCTCTGT GCTGCAGCGGGCAGCCAAGTTCGGTTCACTGGCCAAGCAGAACTCTCAGATGATTGTCAAACGTTTTTCC TTCTCTCAACGGAGCCGGGATGAGAGTGCCTCGGAGACCTCAACCCCCTCAGAGCACTCTGCAGCCCCAT CACCTCAGGTAGAGGTGCGGACGCTTGAGGGACAGCTAATGCAGCATCCTGGGCTAGGCATTCCTCGACC AGGACCACGGTCTCGAGTCCCTGAGCTGGTGACTAAAAGATTCCCAGCTGATCTACGTCTTCCCGCTCTG GTGCCACCACCACCTCCTGCTCTCCGGGAGCTGGAGTTACAACGAAGACCCACAGGAGACTTTGGCTTCT CACTGCGGCGCACAACCATGCTGGATCGGGCCCCTGAGGGTCAGGCTTATCGACGGGTGGTTCACTTTGC TGAGCCAGGGGCAGGCACCAAGGACCTGGCCTTGGGGCTGGTACCAGGAGATCGACTGGTGGAGATTAAT GGACAGAATGTGGAGAATAAATCCAGGGATGAAATTGTGGAGATGATCCGGCAGTCTGGGGACAGTGTGC GGCTCAAGGTACAGCCCATCCCAGAGCTTAGCGAGCTGAGCCGGAGCTGGCTTCGGACTGGCGAGGGACA CCGCAGGGAGCCGGCTGATGCCAAGACGGAAGAGCAGATTGCCGCTGAAGAGGCCTGGTATGAGACGGAG AAGGTGTGGCTGGTCCATAGAGATGGATTCTCCTTAGCCAGCCAGCTCAAGTCTGAGGAGCTCAGCCTAC CCGAGGGGAAGGCGCGTGTGAAGCTGGACCATGACGGAGCCATCCTGGATGTGGATGAAGATGATATAGA GAAGGCTAATGCTCCTTCATGTGACCGTCTAGAAGATCTGGCCTCACTGGTATACCTCAACGAGTCTAGC GTCCTGCATACACTGCGCCAGCGCTATGGGGCTAGCCTGCTACACACCTATGCTGGCCCCAGCCTGCTTG TCCTTAGCACCCGAGGGGCTCCTGCTGTGTATTCAGAGAAGGTGATGCACATGTTCAAGGGGTGTCGGCG GGAGGACATGGCACCCCACATCTACGCTGTAGCCCAGACTGCATATAGGGCGATGTTGATGAGTCGTCAG GACCAGTCCATTGTCCTTCTGGGTAGTAGTGGCAGTGGCAAGACTACCAGCTTTCAGCATCTGGTGCAGT ATCTGGCTACCATCGCGGGTACCAGTGGGACCAAGGTGTTCTCAGTGGAGAAGTGGCAGGCTCTGTCCAC CCTCCTGGAAGCCTTTGGGAACAGCCCCACCATCATGAATGGCAGTGCCACCCGCTTCTCCCAGATCCTC TCCCTGGACTTTGACCAAGCTGGCCAGGTGGCTTCGGCCTCCATCCAGACAATGCTCCTGGAGAAGCTGC GTGTGGCCCGGCGCCCAGCCAGTGAGGCTACTTTCAATGTCTTCTACTACTTGCTGGCCTGTGGGGATGC CACCCTCAGGACAGAGCTCCACCTGAACCACTTGGCAGAGAACAATGTGTTTGGAATTGTGCCACTGTCC AAGCCTGAGGAGAAGCAGAAGGCTGCACAGCAGTTCAGTAAGCTCCAGGCTGCCATGAAGGTGCTGGCCA TCTCCCCCGAGGAACAGAAGACCTGCTGGCTCATCCTGGCTTCCATCTACCACCTGGGGGCTGCTGGAGC TACCAAAGAAGCTGCTGAAGCTGGACGAAAGCAGTTTGCCCGCCACGAATGGGCCCAGAAGGCAGCATAC CTGCTGGGCTGCAGCTTGGAAGAGCTGTCCTCGGCTATCTTCAAACACCAGCTAAAAGGAGGCACCCTGC AACGGTCCACCTCCTTCCGTCAGGGCCCTGAGGAGAGCGGCCTGGGAGAGGGCACCAAACTGAGTGCTCT GGAGTGCTTAGAGGGTATGGCGTCTGGCCTCTACAGTGAGCTCTTTACTCTCCTCATCTCCCTGGTAAAC AGGGCTCTCAAGTCCAGCCAGCACTCACTCTGTTCCATGATGATCGTGGACACACCAGGCTTCCAGAACC CTGAATGGGGCGGCTCGGCCCGTGGAGCCTCCTTCGAGGAGCTGTGCCACAACTATGCCCAGGACAGGCT GCAGAGGCTGTTCCACGAGCGCACCTTCCTCCAGGAGTTGGAGAGATACAAGGAGGATAACATAGAACTG GCGTTTGATGACTTGGAGCCAGTTGCAGATGACTCCGTGGCTGCTGTGGACCAGGCTTCCCACCTGGTTC GCTCACTGGCCCATGCCGATGAGGCAAGAGGGCTACTGTGGCTCCTGGAAGAGGAGGCACTGGTGCCTGG TGCGACAGAGGATGCCCTCCTTGATCGTCTTTTCTCCTATTATGGCCCCCAGGAGGGTGACAAAAAAGGC CAGAGTCCTCTTCTGCGAAGTAGCAAACCTCGGCACTTTCTCCTGGGCCACAGCCACGGTACCAACTGGG TGGAGTACAACGTGGCTGGCTGGCTGAATTACACCAAGCAGAACCCAGCCACCCAGAATGCACCCCGGCT TCTGCAGGACTCCCAGAAAAAGATCATCAGTAACCTGTTTCTGGGCCGGGCGGGCAGTGCCACGGTGCTC TCAGGCTCGATTGCAGGCCTGGAAGGTGGCTCCCAGCTGGCCTTGCGCCGGGCAACCAGCATGAGGAAAA CCTTCACCACCGGCATGGCCGCTGTCAAGAAGAAGTCGCTGTGCATACAGATTAAGCTGCAAGTAGATGC CCTCATTGATACCATCAAGAGGTCCAAGATGCATTTCGTGCACTGCTTCCTTCCTGTGGCCGAGGGCTGG CCTGGGGAGCCCCGGTCTGCCTCTTCCCGCAGAGTCAGCAGCAGCAGTGAGCTGGACCTGCCCCCGGGAG ACCCCTGTGAGGCTGGGCTGCTACAACTGGATGTGTCCCTGCTCCGAGCCCAGCTCCGGGGATCCCGCCT GCTTGATGCGATGCGCATGTACCGCCAAGGTTACCCAGACCACATGGTGTTTTCTGAGTTCCGCCGGCGC TTTGATGTCCTGGCTCCACACCTGACCAAGAAACATGGTCGTAACTACATCGTGGTGGATGAGAAGCGGG CTGTGGAAGAGCTGCTGGAGTCCCTGGACCTGGAAAAGAGCAGCTGCTGTCTGGGCCTAAGCCGGGTGTT CTTCCGGGCAGGCACGTTGGCACGGTTGGAAGAACAACGAGACGAGCAAACCAGCAGGCACCTGACCCTG TTCCAGGCAGCCTGCCGGGGCTACCTTGCCCGCCAGCACTTCAAGAAGAGAAAGATCCAGGACCTGGCCA TTCGCTGTGTGCAGAAGAACATCAAGAAGAACAAGGGGGTGAAGGACTGGCCCTGGTGGAAGCTCTTCAC CACCGTGCGGCCCCTCATCCAAGTTCAGCTGTCAGAGGAGCAGATCCGAAACAAAGACGAGGAGATCCAG CAGCTGCGCAGCAAGCTTGAGAAGGTGGAGAAGGAGAGGAACGAGCTCCGACTCAGCAGTGACCGGCTAG AGACCCGGATCTCAGAACTGACATCGGAGCTGACTGATGAACGCAACACGGGAGAGTCCGCCTCCCAGCT GCTGGACGCGGAGACAGCCGAGAGGCTCCGGACCGAGAAGGAGATGAAAGAGCTACAGACCCAGTATGAC GCACTGAAGAAGCAGATGGAGGTGATGGAGATGGAAGTGATGGAAGCCCGGCTCATTCGGGCAGCCGAGA TCAACGGGGAGGTGGATGATGATGATGCAGGGGGAGAGTGGAGGCTGAAGTACGAGCGAGCTGTTCGGGA GGTGGACTTCACCAAGAAGCGGCTCCAGCAGGAGCTGGAAGACAAGATGGAGGTGGAACAGCAGAGCAGG AGGCAGCTGGAGAGGCGGCTTGGGGACCTGCAAGCAGATAGTGATGAGAGTCAACGGGCACTGCAGCAGC TCAAGAAGAAGTGCCAAAGGCTCACAGCTGAGCTGCAGGACACCAAGCTGCACCTGGAGGGCCAGCAGGT CCGAAACCACGAGCTGGAGAAGAAGCAGAGGAGGTTCGACAGTGAGCTTTCCCAGGCCCACGAGGAGACG CAGCGGGAGAAGCTGCAGAGGGAGAAACTCCAGCGGGAGAAGGACATGCTCCTGGCTGAGGCTTTCAGCT TGAAGCAGCAAATGGAGGAAAAAGACTTGGACATTGCGGGGTTTACCCAGAAGGTGGTTTCCTTGGAGGC TGAGCTTCAGGACATTTCTTCTCAAGAGTCTAAGGATGAGGCTTCTCTGGCCAAGGTCAAGAAGCAGCTC CGGGACTTGGAGGCCAAGGTCAAGGACCAGGAAGAGGAGCTGGATGAGCAGGCTGGGAGTATACAGATGC TGGAGCAGGCCAAGCTGCGTCTGGAGATGGAGATGGAGAGAATGAGACAGACCCATTCCAAGGAGATGGA GAGTCGGGATGAGGAGGTGGAAGAGGCCCGGCAGTCATGTCAGAAGAAGTTAAAACAGATGGAAGTGCAG CTCGAGGAGGAGTATGAAGACAAGCAGAAGGCGCTGCGGGAGAAACGGGAGCTGGAGAGCAAGCTCTCCA CGCTCAGTGACCAGGTGAACCAGCGGGACTTTGAATCAGAGAAGCGGCTACGGAAAGACCTGAAGCGCAC CAAAGCGCTGCTGGCAGATGCCCAGATCATGCTGGACCACTTAAAGAACAATGCCCCGAGCAAGAGGGAG ATTGCCCAGCTGAAGAACCAGCTGGAAGAGTCGGAATTCACCTGTGCAGCAGCTGTAAAGGCACGGAAAG CGATGGAGGTGGAGATGGAAGACCTGCACCTGCAGATTGATGACATCGCCAAAGCCAAGACAGCGCTGGA GGAGCAACTGAGTCGACTTCAGCGTGAGAAAAACGAGATTCAAAACCGGCTGGAAGAGGATCAGGAGGAC ATGAATGAGCTGATGAAGAAGCACAAGGCAGCTGTGGCCCAGGCCTCCCGGGACATGGCACAGATGAACG ATCTCCAGGCTCAGATTGAAGAGTCCAACAAGGAGAAGCAAGAGCTACAGGAGAAGCTACAAGCTCTGCA GAGCCAGGTGGAGTTCCTGGAGCAGTCCATGGTGGACAAGTCCCTCGTCAGCAGGCAGGAAGCGAAGATC AGGGAGCTGGAGACACGCCTGGAGTTCGAAAAGACCCAAGTGAAGCGCCTGGAGAACCTGGCCAGTCGGC TCAAAGAAACCATGGAGAAGCTGACTGAGGAACGGGACCAGCGCGCCGCAGCTGAGAACCGTGAGAAGGA GCAGAACAAGAGGCTCCAGCGACAGCTTCGTGACACCAAGGAGGAGATGAGCGAGCTTGCCAGGAAGGAA GCCGAGGCTAGCCGCAAGAAGCATGAACTGGAGATGGACCTGGAGAGCCTGGAAGCTGCTAACCAAAGCC TGCAAGCCGACCTAAAGCTGGCGTTCAAACGCATTGGGGACTTGCAAGCTGCCATTGAGGATGAGATGGA AAGTGACGAGAACGAGGACCTCATCAACAGTGAGGGGGACTCAGATGTGGACTCAGAGCTGGAGGACCGG GTCGACGGGGTCAAGTCCTGGTTGTCAAAGAACAAGGGACCTTCTAAGGCACCTTCTGACGATGGCAGCT TGAAGAGTTCCAGCCCAACCAGCCACTGGAAGCCACTCGCCCCTGACCCATCGGATGATGAGCATGATCC TGTGGACAGCATCTCCAGACCCCGGTTCTCCCACAGCTATCTGAGTGACAGCGACACAGAGGCCAAGCTG ACAGAGACCAGTGCATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_011586
Insert Size	6108 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_011586.3, NP_035716.1
RefSeq Size	7360 bp
RefSeq ORF	6108 bp
Locus ID	360013
UniProt ID	Q9JMH9
Gene Summary	May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (By similarity). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (PubMed:10733906). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.

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