Kmt2e (NM_026984) Mouse Untagged Clone

CAT#: MC224990

Kmt2e (untagged) - Mouse myeloid/lymphoid or mixed-lineage leukemia 5 (Mll5), (10ug)



  "NM_026984" in other vectors (2)

CNY 29,930.00


货期*
8周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms 1810033J14Rik; 9530077A04Rik; D230038D11Rik; Mll5; NKp44L
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC224990 representing NM_026984
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGAGCATAGCGATCCCATTGGGGGTTGATACAACAGAAACATCCTACTTGGAAATGGCTGCAGGCTCAG
AACCGGAATCCGTAGAAGCTAGCCCTGTGGTAGTTGAGAAATCCAACAGTTTTCCCCACCAGTTATACAC
CAGCAGCTCCCACCACTCACACAGCTACATCGGTCTGCCCTATGCGGACCATAATTATGGTGCTCGTCCT
CCTCCAACACCTCCAGCATCCCCTCCTCCATCAGGTCTCATTAGCAAAAACGAAGTAGGCATATTTACCA
CTCCTAATTTTGATGAAACTTCCAGTGCTACTACAATCAGCACATCTGAAGATGGAAGTTACGGTACTGA
TGTAACCAGGTGCATATGTGGTTTTACACATGATGACGGATACATGATCTGTTGTGACAAATGCAGTGTT
TGGCAACATATTGACTGCATGGGGATTGACAGGCAGCATATTCCTGATACATACCTATGTGAACGTTGTC
AGCCCAGGAGTTTGGATAAAGAGAGGGCAGTGCTACTGCAACGCCGGAAAAGAGAAAATATGTCAGATGG
TGATACCAGTGCAACTGAAAGTGGTGATGAAGTTCCTGTGGAATTATATACTGCATTTCAGCATACTCCA
ACTTCAATCACTTTAACTGCTTCCAGAGTTCCCAAGGTTACTGATAAAAGAAGGAAAAAAAGTGGGGAGA
AAGAACAAAACTTTTCAAAATGTAAAAAAGCCTTTCGTGAAGGATCTAGGAAATCATCAAGGGTTAAGGG
TTCAGCACCAGAAATTGATCCTTCATCTGATAGTTCAAATTTTGTTTGGGAAACAAAAATCAAAGCATGG
ATGGATCGTTACGAAGAAGCAAATAATAACCAATATAGTGAAGGTGTTCAGAGAGAGGCACAAAGACTAG
CTCAAAGACTCGGTAGTGGGAATGACAGCAAAGACATGAATAAATCAGAATTGAGTACCAACAACTCACT
CTTCAGACCTCCTGTAGAGAGCCATATACAGAAGAATAAAAAAATTCTGAAATCTGCCAAAGACTTGCCT
CCTGATGCACTTATCATTGAATATAGAGGGAAGTTTATGCTGAGAGAACAGTTTGAAGCAAATGGATATT
TCTTTAAAAGGCCATACCCTTTTGTTTTATTCTACTCTAAGTTCCATGGGCTTGAAATGTGTGTTGATGC
GAGGACTTTTGGGAATGAGGCTCGATTCATCAGGCGTTCTTGTACACCGAATGCAGAGGTGAGGCATGAA
ATTGAAGAGGGGACCATACATCTCTACATTTATTCTATACAGAGTATTCCAAAAGGGACTGAAATTACCA
TTGCCTTTGATTTTGACTACGGGAATTGCAAATACAAGGTGGACTGTGCATGCCTCAAGGAAAATCCAGA
GTGCCCTGTTCTCAAGCGAAGCTCGGAATCCACAGAAAACATCAATAGTGGTTATGAGACCAGAAGGAAA
AAAGGAAAAAAAGAGAAAGATACTTCAAAAGAAAAAGACATACAAAATCAGAATATGACTTTGGACTGTG
AAGGAACAAACAACAAAATAAGGAGTCCAGAAACAAAACAGAGAAAGCTTTCTCCATTGAGGCTGTCGGT
GTCAAACAACCAGGAACCAGATTTTATTGATGATATGGAAGAAAAAACTCCTATTAGCAATGAAGTGGAA
ATGGAATCTGAGGAACAGATTGCAGAAAGGAAAAGGAAGATGACAAGAGAAGAAAGAAAAATGGAAGCAA
TTTTGCAGGCTTTTGCCAGACTTGAGAAGAGAGAGAAAAGACGAGAACAAGCTTTGGAAAGGATCAGCAC
AGCTAAGACAGAAGTTAAGCCTGAATGCAAAGAGTCGCAGGTCATCGCCGATGCCGAAGTGGTGCAGGAA
CAAGTAAAAGAAGAAACTGCTATCAAGCCAGCCGCTGCCAAAGTGAACAGAACTAAGCAGAGAAAGAGCT
TTTCTCGTAGTAGGACTCACATTGGACAGCAGCGTCGGAGACACAGAACTGTCAGCATGTGTTCAGACAT
ACCGCCATCTTCTCCTGACATCGAAGTTCTGTCACAACAGAACGAGATTGAAAATACTGTACTTGCTATA
GAACCAGAAACTGAAACTGCAGTAGCAGAAATAATTCCTGAAGCGGAAGTTCCAGCACTTAATAAGTGTC
CCACAAAGTACCCCAAAACAAAGAAGCACTTGGTCAATGAATGGTTAAGTGAGAAGAATGAGAAGACAGG
AAAACCTTCAGACAGCCTTTCAGAAAGGCCTCTGCGCATAACTACAGATCCAGAGGTGTTAGCTACACAG
CTCAATTCTTTGCCAGGTCTCACTTACAGCCCCCATGTATACTCTACTCCTAAGCATTATATTAGATTTA
CATCACCATTCCTTTCGGAAAAAAAGAGAAGAAAAGAAACTACTGAAAACATTTCTGGCTCATGCAAAAA
GCGGTGGCTGAAGCAAGCCCTGGAGGAAGAAAATTCAACAATTTTACATAGATATCATTCACCTTGTCAG
GAAAGATCCAGGAGTCCTACAGTTAATGGTGAAAACAAAAGTCCACTTCTGCTAAGCGACAGCTGCTCCC
TCCCAGATTTAACCACACCACTAAAAAAGCGAAGACTTTACCAATTGTTAGATACTGCTTACTCAGAAAG
CTCCACTCCTACCCCTTCACCATATGCTACACCAACTCACACAGACATCACTCCTACGGACCCAGCATTT
GCCACTCCCCCACGGATCAAATCAGATGATGAAACTTACAGAAATGGTTATAAACCCATATATTCACCAG
TGACCCCTGTAACCCCTGGCACACCAGGAAACACCATGCACTTTGAGAATATTTCTTCCCCAGAAAGTTC
TCCAGAAATAAAGAGATGCACTTACAATCAAGAGGGATATGACCGACCTTCAAACATGCTAACGTTGGGG
CCTTTTAGAAATTCCAATTTAACTGAGCTGGGCCTGCAAGAAATAAAGACTATTGGTTATACCAGCCCTA
GGAGCAGGACTGAGGTTAACAGGCCTTGCCCAGGGGAGAAGGAGTCTGTGTCAGACCTTCAACTGGGACT
CGATGCAGTCGAGCCAGCTGCCTTACAGAAATCCATGGAAACACCAGCCCATGACAGGACTGAGCCCAGC
AACCAACTGGATTCGACCCACTCTGGACGGGGCACAATGTATTCATCCTGGGTAAAGAGTCCTGACAGAA
CAGGAGTTAACTTCTCAGTAAACTCCAACTTGAGGGACTTAACACCCTCTCATCAGTTGGAGACTGGAGG
CGGCTTCCGAGTAAGTGAGTCCAAGTGCCTGATTCAGCAGGATGACACTAGAGGCATGTTTCTGGGAGCG
GCTGTCTTTTGTACTTCTGAAGACGGGCTTGCCTCTGGTTTTGGACGGACTGTTAATGACAATTTGATCG
ACGGGAGTTGCACGCCCCAGAATCCACCACAAAAGAAAAAGGTTTCTCTATTAGAATACCGTAAGAGACA
ACGTGAAGCTAGGAAGAGTGGGTCTAAGCCAGAGAACTTTGCTTTGATTAGTGTGTCACCTCACCCGAGT
GGGAGCCTGAGCAGCAGTGGCGACGGGTGTGTCCACAGCAGTGAAAACGGGGAGCAGGCAGAAAACCAGG
CTAGCTTGCCTTTACCACCGCCTGCTGCCGCCGCCGCCGCCACCGCCGCCGCCGCTTACAGTGCCTCTTC
TGAAGAAGGCAGCAGTAACTGTCCTGTTAAAGACGCCAATTCCAGTGAGAAGAAAGACCCAGAAGTTCAG
TGGACTGCCTCCACTTCAGTGGAGCAAGTGAGAGAGAGAAGTTACCAGAGAGCCTTACTGCTCAGTGACC
ACCGCAAAGACAAAGACAGTGGGGGAGAGTCACCATGTGTCTCATGCTCACCGAGTCATGTTCAGTCTCC
ACCTTCATCTCATTCAAATCACATTCCCCAGGTGCACGCTCAGAGCCTAGCTCCTTCTTTGAGTGAACTC
ATGGCAGACCCTGATGCGGAAGGTACAGAAGCCACAAGTACAAGTGAATGTCCATCCCCTGACACTTCTC
AGAGCCCTTCTAAAACAAGCAAGCCTGGTTCACCAGGGCCAATCAATCCTGCTCAGTCACATGGGAAAAT
ACTCACAAAACCAGATAGCCACTGGGAGGCAACTGCCACTGTATCAGAAGCTGACAACAGTGTTCACCAA
AACCCAGAGCCTCAGCACAGACAGCTGTCAAGTAACACCCCAGCACTTTCTCAGAACCATGCTCCTCAGG
CCCACGCTCTGAGTGCGAATGATCAACTTCCGCAAAAGCTGCCTTCTGCACCGACGAAGTTGCACTGTCC
TCCGTCACCTCACACAGAAAACCCTCCCAAGTCCTCCACACCTCACACCCCCGTGCAGCATGGTTACCTC
TCGCCAAAGCCTCCTTCACAGCACTTAGGATCTCCCTTCAGGCCTCACCATTCACAATCACCTCAAGTTG
GAACTCCTCAACGAGAGACTCAGAGAAACTTTTATGCAGCGGCACAGAACCTTCAAGCTAATCCTCAGCA
GGCAACTTCTGGAGCGTTATTTACCCAGACACCCTCAGGACAATCTTCAGCAACCTACAGTCAGTTCAAC
CAACAGAGTCTCAACAGCACGGCCCCACCCCCTCCCCCTCCTCCCCCTCCTTCATCCTACTATCAAAACC
AGCAGCCCTCTGCAAACTTTCAGAATTATAATCAGCTAAAAGGTAGTCTTTCCCAACAAACTGTGTTTAC
ATCTGGACCAAATCAAGCACTTCCTGGCAGCACCAGCCAGCAATCAGTTCCTGGACATCACGTTACTCCA
GGGCATTTTCTGCCATCTCAAAACCCCACCATTCACCATCAACCTGCTGCTGCTGCTGTGGTCCCGCCCC
CGCCCCCACCCCCGCCCGCTCCAGGACCACACCTCATACAGCAGCCAAGCTCACATCAGCAGCACTCTGT
AGCACATGGAGTTGGGCCAGTTCATGCTGTTACCCCTGGGTCACACATTCATTCTCAAACTGCAGGACAC
CATTTACCACCACCCCCTCCACCACCTGGTCCTGCCCCACATCACCATCCCCCACCCCATCCTACCACGG
GACTGCAAAGTCTACAAGCACAACACCAGCATGTAGTAAACTCGGCACCCCCGCCCCCTCCCCCTCCCCC
GCCCCCTCCCCCAGCCAGTGTTCTGGTTTCTGGGCATCATTCAGCATCAGGTCAAGCCTTACACCACCCA
CCTCATCAAGGACCTCCACTTTTCCCTGCAAGCGCTCATCCAGCTGTCCCGCCGTACCCCTCACAAGCCA
CACATCATACCACTTTGGGACCGGGACCCCAACACCAGCCTTCCGGAACAGGGCCACATTGTCCATTACC
AGTTGCAGGTCCTCATCTCCAGCCCCAAGGACCAAACAGTATTCCAACCCCTACTGCTTCAGGGTTCTGT
CCTCATCCTCATCCTGGCTCTGTGGCCCTGCCACATGGGGTGCAAGGACCTCAGCAGGCATCGCCAGTGC
CTGCACAGATTCCAATTCACAGAGCACAGGTGCCGCCGACATTTCAAAACAATTACCACGGTTCAGGGTG
GCATTAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_026984
Insert Size 5607 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_026984.1, NP_081260.1
RefSeq Size 7258 bp
RefSeq ORF 5607 bp
Locus ID 69188
UniProt ID Q3UG20
Gene Summary Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription (By similarity). Chromatin interaction is mediated via the binding to tri-methylated histone H3 at 'Lys-4' (H3K4me3) (By similarity). Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation (PubMed:18854576, PubMed:18952892, PubMed:18818388). Also acts as an important cell cycle regulator, participating in cell cycle regulatory network machinery at multiple cell cycle stages including G1/S transition, S phase progression and mitotic entry (PubMed:19264965). Recruited to E2F1 responsive promoters by HCFC1 where it stimulates tri-methylation of histone H3 at 'Lys-4' and transcriptional activation and thereby facilitates G1 to S phase transition (By similarity). During myoblast differentiation, required to suppress inappropriate expression of S-phase-promoting genes and maintain expression of determination genes in quiescent cells (PubMed:19264965).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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